Zobrazeno 1 - 10 of 75 pro vyhledávání: '"Gramoun A"'
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Akademický článek
Digital tools for the clinical evaluation of medical devices: A guide to empower regulatory writers.
Autor: Gramoun, Azza1 azza.gramoun@gmail.com
Publikováno v: Medical Writing. Sep2023, Vol. 32 Issue 3, p16-21. 6p.
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Improved dynamic response assessment for intra-articular injected iron oxide nanoparticles
Autor: Kerstin Grosdemange, J Salaklang, Anthony Redjem, Bénédicte M. A. Delattre, Frank Tobalem, Lindsey A. Crowe, Alke Petri-Fink, Jean-Paul Vallée, Heinrich Hofmann, Azza Gramoun
Publikováno v: Magnetic Resonance in Medicine. 68:1544-1552
The emerging importance of nanoparticle technology, including iron oxide nanoparticles for monitoring development, progression, and treatment of inflammatory diseases such as arthritis, drives development of imaging techniques. Studies require an ima
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca88a733ede401d9abe184dd59ee2f0d
https://doi.org/10.1002/mrm.24166
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4
Fibronectin inhibits osteoclastogenesis while enhancing osteoclast activity via nitric oxide and interleukin-1β-mediated signaling pathways
Autor: Azza Gramoun, Natoosha Azizi, Johan N. M. Heersche, Morris F. Manolson, Jaro Sodek, Inaam A. Nakchbandi
Publikováno v: Journal of Cellular Biochemistry. 111:1020-1034
Osteoclasts are bone-resorbing cells formed by fusion of mononuclear precursors. The matrix proteins, fibronectin (FN), vitronectin (VN), and osteopontin (OPN) are implicated in joint destruction and interact with osteoclasts mainly through integrins
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feb823c7538ff5b44b8b3f7ed04a040e
https://doi.org/10.1002/jcb.22791
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5
Bone matrix proteins and extracellular acidification: Potential co-regulators of osteoclast morphology
Autor: Ori D. Rotstein, Morris F. Manolson, Tetsuya Goto, Azza Gramoun, Tommy Nordström, Johan N. M. Heersche, Sergio Grinstein
Publikováno v: Journal of Cellular Biochemistry. 111:350-361
Osteoclasts are signaled by the bone matrix proteins fibronectin (FN), vitronectin (VN), and osteopontin (OPN) via integrins. To perform their resorptive function, osteoclasts cycle between compact (polarized), spread (non-resorbing) and migratory mo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec116139fa8f05eb178a15324c9941ca
https://doi.org/10.1002/jcb.22705
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6
Increased expression of activating factors in large osteoclasts could explain their excessive activity in osteolytic diseases
Autor: Johan N. M. Heersche, Morris F. Manolson, Divya Chandra, Diana P. Trebec, Azza Gramoun, Keying Li
Publikováno v: Journal of Cellular Biochemistry. 101:205-220
Large osteoclasts (>or=10 nuclei) predominate at sites of pathological bone resorption. We hypothesized this was related to increased resorptive activity of large osteoclasts and have demonstrated previously that larger osteoclasts are 8-fold more li
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab4f9a1e060a15d7077eb1d08a56a6f4
https://doi.org/10.1002/jcb.21171
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Effects of Vitaxin®, a novel therapeutic in trial for metastatic bone tumors, on osteoclast functions in vitro
Autor: Jill D. Bashutski, Morris F. Manolson, S. Jeffrey Dixon, Stephen M. Sims, Johan N. M. Heersche, Seema Shorey, Azza Gramoun
Publikováno v: Physiology and Pharmacology Publications
The integrin alphavbeta3 mediates cell-matrix interactions. Vitaxin(R), a humanized monoclonal antibody that blocks human and rabbit alphavbeta3 integrins, is in clinical trials for metastatic melanoma and prostate cancer. alphavbeta3 is the predomin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9102594b2d3e893fdfd4d92a590e0012
https://doi.org/10.1002/jcb.21296
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Amino-polyvinyl Alcohol Coated Superparamagnetic Iron Oxide Nanoparticles are Suitable for Monitoring of Human Mesenchymal Stromal Cells In Vivo
Autor: Peter Guttmann, Frank Schulze, Paul Zaslansky, Anke Dienelt, Lindsey A. Crowe, Georg N. Duda, Janosch Schoon, Jean-Paul Vallée, Azza Gramoun, Heinrich Hofmann, Sven Geissler, Lionel Maurizi, Andrea Ode, Katja Henzler
Publikováno v: Small, Vol. 10, No 21 (2014) pp. 4340-4351
Small
Small, Wiley-VCH Verlag, 2014, pp.n/a-n/a. ⟨10.1002/smll.201400707⟩
Mesenchymal stromal cells (MSCs) are promising candidates in regenerative cell-therapies. However, optimizing their number and route of delivery remains a critical issue, which can be addressed by monitoring the MSCs' bio-distribution in vivo using s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a57a26d9d1feff30a6ce774a6263b685
https://doi.org/10.1002/smll.201400707
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9
A fast and reproducible method to quantify magnetic nanoparticle biodistribution
Autor: Usawadee Sakulkhu, Heinrich Hofmann, Azza Gramoun, Lionel Maurizi, Jean-Paul Vallée
Publikováno v: The Analyst
The Analyst, Vol. 139, No 5 (2014) pp. 1184-1191
Analyst
Analyst, Royal Society of Chemistry, 2014, 139 (5), pp.1184-1191. ⟨10.1039/C3AN02153J⟩
International audience; The quantification of nanoparticles, particularly superparamagnetic iron oxide nanoparticles (SPION), both in vitro and in vivo has become highly important in recent years. Some methods, such as induced coupled plasma spectros
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf4453e5f3f0ebcc8e3791368230cfeb
https://pubmed.ncbi.nlm.nih.gov/24448415
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Monitoring the effects of dexamethasone treatment by MRI using in vivo iron oxide nanoparticle-labeled macrophages
Autor: Heinrich Hofmann, Wolfgang Wirth, Kerstin Grosdemange, Lindsey A. Crowe, Lionel Maurizi, Marije I. Koenders, Frank Tobalem, Géraldine Coullerez, Azza Gramoun, Felix Eckstein, Jean-Paul Vallée, Wim B. van den Berg
Publikováno v: Arthritis Research and Therapy
Arthritis Research and Therapy, BioMed Central, 2014, 16 (3), pp.R131. ⟨10.1186/ar4588⟩
Arthritis Research & Therapy, Vol. 16, No 3 (2014) P. R131
Arthritis Research & Therapy
Arthritis Research & Therapy, 16, 3, pp. R131
Arthritis Research & Therapy, 16, R131
Contains fulltext : 137472.pdf (Publisher’s version ) (Open Access) INTRODUCTION: Rheumatoid arthritis (RA) is a chronic disease causing recurring inflammatory joint attacks. These attacks are characterized by macrophage infiltration contributing t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33f8c921c85d460ce7f817807d0d80b1
https://hal.archives-ouvertes.fr/hal-02163410/document
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