The genetic determinants of recurrent somatic mutations in 43,693 blood genomes.

Autor: Weinstock JS; Center for Statistical Genetics, Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA., Laurie CA; Department of Biostatistics, University of Washington, Seattle, WA 98195, USA., Broome JG; Department of Biostatistics, University of Washington, Seattle, WA 98195, USA.; Division of Medical Genetics, Department of Medicine, University of Washington, Seattle, WA 98195, USA., Taylor KD; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA 90502, USA., Guo X; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA 90502, USA., Shuldiner AR; Department of Medicine, University of Maryland, Baltimore, Baltimore, MD 21201, USA., O'Connell JR; Department of Medicine, University of Maryland, Baltimore, Baltimore, MD 21201, USA., Lewis JP; Department of Medicine, University of Maryland, Baltimore, Baltimore, MD 21201, USA., Boerwinkle E; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA., Barnes KC; Division of Biomedical Informatics and Personalized Medicine, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA., Chami N; The Charles Bronfman Institute of Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; The Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Kenny EE; Institute for Genomic Health, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Loos RJF; The Charles Bronfman Institute of Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; The Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Fornage M; Brown Foundation Institute of Molecular Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX 77030, USA., Redline S; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.; Harvard Medical School, Boston, MA 02115, USA., Cade BE; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.; Harvard Medical School, Boston, MA 02115, USA.; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA., Gilliland FD; Department of Preventive Medicine, University of Southern California, Los Angeles, CA 90089, USA., Chen Z; Department of Preventive Medicine, University of Southern California, Los Angeles, CA 90089, USA., Gauderman WJ; Department of Preventive Medicine, University of Southern California, Los Angeles, CA 90089, USA., Kumar R; Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, IL 60611, USA.; Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA., Grammer L; Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA., Schleimer RP; Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA., Psaty BM; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA 98195, USA.; Department of Epidemiology, University of Washington, Seattle, WA 98195, USA.; Department of Medicine, University of Washington, Seattle, WA 98195, USA., Bis JC; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA 98195, USA., Brody JA; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA 98195, USA., Silverman EK; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA., Yun JH; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA., Qiao D; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA., Weiss ST; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA., Lasky-Su J; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA., DeMeo DL; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA., Palmer ND; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC 27101, USA., Freedman BI; Department of Internal Medicine, Section on Nephrology, Wake Forest School of Medicine, Winston-Salem, NC 27101, USA., Bowden DW; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC 27101, USA., Cho MH; Channing Division of Network Medicine and Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA., Vasan RS; National Heart, Lung, and Blood Institute's, Boston University's Framingham Heart Study, Framingham, MA 01701, USA., Johnson AD; National Heart, Lung, and Blood Institute's, Boston University's Framingham Heart Study, Framingham, MA 01701, USA.; National Heart, Lung and Blood Institute, Population Sciences Branch, Framingham, MA 01701, USA., Yanek LR; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Becker LC; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Kardia S; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI 48109, USA., He J; Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA 70112, USA., Kaplan R; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY 10461, USA., Heckbert SR; Department of Epidemiology, University of Washington, Seattle, WA 98195, USA.; Kaiser Permanente Washington Health Research Institute, Kaiser Permanente Washington, Seattle, WA 98101, USA., Smith NL; Department of Epidemiology, University of Washington, Seattle, WA 98195, USA.; Kaiser Permanente Washington Health Research Institute, Kaiser Permanente Washington, Seattle, WA 98101, USA.; Seattle Epidemiologic Research and Information Center, Department of Veterans Affairs Office of Research and Development, Seattle, WA 98108, USA., Wiggins KL; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA 98101, USA., Arnett DK; Dean's Office, College of Public Health, University of Kentucky, Lexington, KY 40506, USA., Irvin MR; University of Alabama at Birmingham, Birmingham, AL 35294, USA., Tiwari H; University of Alabama at Birmingham, Birmingham, AL 35294, USA., Correa A; Department of Medicine, Jackson Heart Study, University of Mississippi Medical Center, Jackson, MS 39216, USA., Raffield LM; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Gao Y; Department of Medicine, University of Mississippi Medical Center, Jackson, MS 39216, USA., de Andrade M; Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA., Rotter JI; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA 90502, USA., Rich SS; Department of Public Health Sciences, Center for Public Health Genomics, University of Virginia, Charlottesville, VA 22903, USA., Manichaikul AW; Department of Public Health Sciences, Center for Public Health Genomics, University of Virginia, Charlottesville, VA 22903, USA., Konkle BA; Department of Medicine, University of Washington, Seattle, WA 98195, USA., Johnsen JM; Department of Medicine, University of Washington, Seattle, WA 98195, USA.; Research Institute, Bloodworks Northwest, Seattle, WA 98102, USA., Wheeler MM; Genome Science, University of Washington, Seattle, WA 98195, USA., Custer BS; Vitalant Research Institute, San Francisco, CA 94105, USA., Duggirala R; Department of Human Genetics, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX 78520, USA.; South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX 78520, USA., Curran JE; Department of Human Genetics, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX 78520, USA.; South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX 78520, USA., Blangero J; Department of Human Genetics, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX 78520, USA.; South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX 78520, USA., Gui H; Center for Individualized and Genomic Medicine Research (CIGMA), Henry Ford Health System, Detroit, MI 48202, USA.; Department of Medicine, Henry Ford Health System, Detroit, MI 48202, USA., Xiao S; Center for Individualized and Genomic Medicine Research (CIGMA), Henry Ford Health System, Detroit, MI 48202, USA.; Department of Medicine, Henry Ford Health System, Detroit, MI 48202, USA., Williams LK; Center for Individualized and Genomic Medicine Research (CIGMA), Henry Ford Health System, Detroit, MI 48202, USA.; Department of Medicine, Henry Ford Health System, Detroit, MI 48202, USA., Meyers DA; Division of Genetics, Genomics, and Precision Medicine, University of Arizona, Tucson, AZ 85721, USA., Li X; Department of Medicine, University of Arizona, Tucson, AZ 85721, USA., Ortega V; Wake Forest University School of Medicine, Winston-Salem, NC 27101, USA., McGarvey S; Department of Epidemiology and International Health Institute, Brown University School of Public Health, Providence, RI 02903, USA., Gu CC; Division of Biostatistics, Washington University School of Medicine, Campus Box 8067, 660 S. Euclid Avenue, St. Louis, MO 63110, USA., Chen YI; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA 90502, USA., Lee WJ; Department of Medical Research, Taichung Veterans General Hospital, 1650, Sec. 4, Taiwan Boulevard, Taichung City, Taiwan., Shoemaker MB; Division of Cardiology, Vanderbilt University Medical Center, Nashville, TN 37232, USA., Darbar D; Division of Cardiology, University of Illinois at Chicago, Chicago, IL 60607, USA., Roden D; Departments of Medicine, Pharmacology, and Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN 37232, USA., Albert C; Department of Cardiology, Cedars-Sinai, Los Angeles, CA 90048, USA., Kooperberg C; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA., Desai P; Division of Hematology and Oncology, Weill Cornell Medicine, New York, NY 10065, USA.; Englander Institute of Precision Medicine, Weill Cornell Medicine, New York 10065, NY, USA., Blackwell TW; Center for Statistical Genetics, Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA., Abecasis GR; Center for Statistical Genetics, Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA.; Regeneron Pharmaceuticals, Tarrytown, NY 10591, USA., Smith AV; Center for Statistical Genetics, Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA., Kang HM; Center for Statistical Genetics, Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA., Mathias R; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Natarajan P; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA 02114, USA.; Department of Medicine, Harvard Medical School, Boston, MA 02115, USA., Jaiswal S; Department of Pathology, Stanford University, Stanford, CA 94305, USA., Reiner AP; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.; Department of Epidemiology, University of Washington, Seattle, WA 98195, USA., Bick AG; Division of Genetic Medicine, Department of Medicine, Vanderbilt University, Nashville, TN 37232, USA.

Publikováno v: Science advances [Sci Adv] 2023 Apr 28; Vol. 9 (17), pp. eabm4945. Date of Electronic Publication: 2023 Apr 26.

M102 A CASE OF DELAYED UVULAR ANGIOEDEMA AFTER ADMINISTRATION OF THE COVID-19 VACCINE

Autor: Kim, S., Mambetsariev, N., Grammer, L.

Publikováno v: In Annals of Allergy, Asthma & Immunology November 2021 127(5) Supplement:S82-S83

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Monoclonal Antibody Switching in Biologic Treatment of Chronic Rhinosinusitis with Nasal Polyps.

Autor: Habenbacher, Michael¹ (AUTHOR), Moser, Ulrich¹ (AUTHOR), Hadl, Oliver¹ (AUTHOR), Kiss, Peter¹ (AUTHOR), Holzmeister, Clemens¹ (AUTHOR), Pock, Jakob¹ (AUTHOR), Walla, Katharina¹ (AUTHOR), Lang, Angelika¹ (AUTHOR), Andrianakis, Alexandros¹ (AUTHOR) alexandros.andrianakis@medunigraz.at

Publikováno v: Journal of Clinical Medicine. Nov2024, Vol. 13 Issue 22, p6883. 9p.

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