Zobrazeno 1 - 10
of 570
pro vyhledávání: '"Grammas P"'
Autor:
Grammas Paula
Publikováno v:
Journal of Neuroinflammation, Vol 8, Iss 1, p 26 (2011)
Abstract Alzheimer's disease (AD) is an age-related disorder characterized by progressive cognitive decline and dementia. Alzheimer's disease is an increasingly prevalent disease with 5.3 million people in the United States currently affected. This n
Externí odkaz:
https://doaj.org/article/65f1d2137fab4451954506687e17d27d
Publikováno v:
Journal of Neuroinflammation, Vol 7, Iss 1, p 63 (2010)
Abstract Background Most neurodegenerative diseases are age-related disorders; however, how aging predisposes the brain to disease has not been adequately addressed. The objective of this study is to determine whether expression of proteins in the ce
Externí odkaz:
https://doaj.org/article/ef4033f728464ad0baab0bcfcce695ed
Autor:
Grammas Paula, Tripathy Debjani
Publikováno v:
Journal of Neuroinflammation, Vol 6, Iss 1, p 10 (2009)
Abstract Background Recent studies have demonstrated a link between the inflammatory response, increased cytokine formation, and neurodegeneration in the brain. The beneficial effects of anti-inflammatory drugs in neurodegenerative diseases, such as
Externí odkaz:
https://doaj.org/article/433deb4eb74449d78f85efa5ac7c9b9b
Publikováno v:
Current Issues in Molecular Biology, Vol 43, Iss 1, Pp 215-225 (2021)
Mutations to the cholesterol transport protein apolipoprotein E (ApoE) have been identified as a major risk factor for the development of sporadic or late-onset Alzheimer’s disease (AD), with the e4 allele representing an increased risk and the rar
Externí odkaz:
https://doaj.org/article/1a2823261b964972accd80c50d1493a8
Autor:
Jaclyn Iannucci, Paula Grammas
Publikováno v:
Cells, Vol 12, Iss 9, p 1222 (2023)
Neurodegenerative diseases, including Alzheimer’s disease (AD), are major contributors to death and disability worldwide. A multitude of evidence suggests that neuroinflammation is critical in neurodegenerative disease processes. Exploring the key
Externí odkaz:
https://doaj.org/article/2d153eb7759349fe80fd05755511c708
Publikováno v:
Cerebral Circulation - Cognition and Behavior, Vol 2, Iss , Pp 100014- (2021)
Background: Vascular risk factors such as atherosclerosis, diabetes, and elevated homocysteine levels are strongly correlated with onset of Alzheimer's disease (AD). Emerging evidence indicates that blood coagulation protein thrombin is associated wi
Externí odkaz:
https://doaj.org/article/c2c83101daef4c86bf2e9b6a1b98fcd5
Autor:
Jaclyn Iannucci, Shelby L. Johnson, Mark Majchrzak, Benjamin J. Barlock, Fatemeh Akhlaghi, Navindra P. Seeram, Abhik Sen, Paula Grammas
Publikováno v:
Biochemistry and Biophysics Reports, Vol 24, Iss , Pp 100862- (2020)
Proteins that regulate the coagulation cascade, including thrombin, are elevated in the brains of Alzheimer's disease (AD) patients. While studies using amyloid-based AD transgenic mouse models have implicated thrombin as a protein of interest, the r
Externí odkaz:
https://doaj.org/article/03ac6d10deab459f80d89734a98f9d4e
Akademický článek
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Publikováno v:
In Microvascular Research March 2012 83(2):138-145
Publikováno v:
In Neuroscience Research 2012 72(1):1-8