Troriluzole rescues glutamatergic deficits, amyloid and tau pathology, and synaptic and memory impairments in 3xTg-AD mice.

Autor: Pfitzer J; Department of Drug Discovery and Development, Auburn University, Auburn, Alabama, USA., Pinky PD; Department of Drug Discovery and Development, Auburn University, Auburn, Alabama, USA., Perman S; Department of Drug Discovery and Development, Auburn University, Auburn, Alabama, USA., Redmon E; Department of Drug Discovery and Development, Auburn University, Auburn, Alabama, USA., Cmelak L; Department of Psychological Sciences, Auburn University, Auburn, Alabama, USA., Suppiramaniam V; Department of Drug Discovery and Development, Auburn University, Auburn, Alabama, USA.; Center for Neuroscience Initiative, Auburn University, Auburn, Alabama, USA.; Department of Molecular and Cellular Biology, College of Science and Mathematics, Kennesaw State University, Kennesaw, Georgia, USA., Coric V; Biohaven Pharmaceuticals Inc., New Haven, Connecticut, USA., Qureshi IA; Biohaven Pharmaceuticals Inc., New Haven, Connecticut, USA., Gramlich MW; Center for Neuroscience Initiative, Auburn University, Auburn, Alabama, USA.; Department of Physics, Auburn University, Auburn, Alabama, USA., Reed MN; Department of Drug Discovery and Development, Auburn University, Auburn, Alabama, USA.; Center for Neuroscience Initiative, Auburn University, Auburn, Alabama, USA.

Publikováno v: Journal of neurochemistry [J Neurochem] 2025 Jan; Vol. 169 (1), pp. e16215. Date of Electronic Publication: 2024 Aug 30.

Myofascial trigger point (MTrP) size and elasticity properties can be used to differentiate characteristics of MTrPs in lower back skeletal muscle.

Autor: Tsai P; College of Nursing, Auburn University, Auburn, AL, USA., Edison J; Edward Via College of Osteopathic Medicine, Auburn University, Auburn, AL, USA., Wang C; Department of Educational Foundations, Leadership, and Technology, College of Education, Auburn University, Auburn, AL, USA., Sefton J; School of Kinesiology, College of Education, Auburn University, Auburn, AL, USA., Manning KQ; Department of Educational Foundations, Leadership, and Technology, College of Education, Auburn University, Auburn, AL, USA., Gramlich MW; Department of Physics, College of Science and Mathematics, Auburn University, Auburn, AL, USA. mwg0016@auburn.edu.

Publikováno v: Scientific reports [Sci Rep] 2024 Mar 30; Vol. 14 (1), pp. 7562. Date of Electronic Publication: 2024 Mar 30.

A kinesin-1 adaptor complex controls bimodal slow axonal transport of spectrin in Caenorhabditis elegans.

Autor: Glomb O; Department of Neuroscience, Yale School of Medicine, New Haven, CT 06510, USA., Swaim G; Department of Neuroscience, Yale School of Medicine, New Haven, CT 06510, USA; Department of Cell Biology, Yale School of Medicine, New Haven, CT 06510, USA., Munoz LLancao P; Department of Cell Biology, Yale School of Medicine, New Haven, CT 06510, USA., Lovejoy C; Department of Cell Biology, Yale School of Medicine, New Haven, CT 06510, USA., Sutradhar S; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06510, USA., Park J; Department of Neuroscience, Yale School of Medicine, New Haven, CT 06510, USA., Wu Y; Department of Genetics, Yale School of Medicine, New Haven, CT 06510, USA., Cason SE; Department of Physiology, University of Pennsylvania, Philadelphia, PA 19104, USA; Neuroscience Graduate Group, University of Pennsylvania, Philadelphia, PA 19104, USA., Holzbaur ELF; Department of Physiology, University of Pennsylvania, Philadelphia, PA 19104, USA; Pennsylvania Muscle Institute, University of Pennsylvania, Philadelphia, PA 19104, USA., Hammarlund M; Department of Neuroscience, Yale School of Medicine, New Haven, CT 06510, USA; Department of Genetics, Yale School of Medicine, New Haven, CT 06510, USA., Howard J; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06510, USA; Quantitative Biology Institute, Yale University, New Haven, CT 06510, USA., Ferguson SM; Department of Cell Biology, Yale School of Medicine, New Haven, CT 06510, USA., Gramlich MW; Department of Physics, Auburn University, Auburn, AL 36832, USA., Yogev S; Department of Neuroscience, Yale School of Medicine, New Haven, CT 06510, USA. Electronic address: shaul.yogev@yale.edu.

Publikováno v: Developmental cell [Dev Cell] 2023 Oct 09; Vol. 58 (19), pp. 1847-1863.e12. Date of Electronic Publication: 2023 Sep 25.

Myosin V Regulates Spatial Localization of Different Forms of Neurotransmitter Release in Central Synapses.

Autor: Maschi D; Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, MO, United States., Gramlich MW; Physics Department, Auburn University, Auburn, AL, United States., Klyachko VA; Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, MO, United States.

Publikováno v: Frontiers in synaptic neuroscience [Front Synaptic Neurosci] 2021 Apr 15; Vol. 13, pp. 650334. Date of Electronic Publication: 2021 Apr 15 (Print Publication: 2021).

Nanoscale Organization of Vesicle Release at Central Synapses.

Autor: Gramlich MW; Department of Cell Biology and Physiology, Department of Biomedical Engineering, Washington University School of Medicine, St. Louis, MO, USA; Present address: Department of Physics, Auburn University, Auburn, AL, USA., Klyachko VA; Department of Cell Biology and Physiology, Department of Biomedical Engineering, Washington University School of Medicine, St. Louis, MO, USA. Electronic address: klyachko@wustl.edu.

Publikováno v: Trends in neurosciences [Trends Neurosci] 2019 Jun; Vol. 42 (6), pp. 425-437.