Integrated intracellular organization and its variations in human iPS cells

Autor: Matheus P. Viana, Jianxu Chen, Theo A. Knijnenburg, Ritvik Vasan, Calysta Yan, Joy E. Arakaki, Matte Bailey, Ben Berry, Antoine Borensztejn, Eva M. Brown, Sara Carlson, Julie A. Cass, Basudev Chaudhuri, Kimberly R. Cordes Metzler, Mackenzie E. Coston, Zach J. Crabtree, Steve Davidson, Colette M. DeLizo, Shailja Dhaka, Stephanie Q. Dinh, Thao P. Do, Justin Domingus, Rory M. Donovan-Maiye, Alexandra J. Ferrante, Tyler J. Foster, Christopher L. Frick, Griffin Fujioka, Margaret A. Fuqua, Jamie L. Gehring, Kaytlyn A. Gerbin, Tanya Grancharova, Benjamin W. Gregor, Lisa J. Harrylock, Amanda Haupt, Melissa C. Hendershott, Caroline Hookway, Alan R. Horwitz, H. Christopher Hughes, Eric J. Isaac, Gregory R. Johnson, Brian Kim, Andrew N. Leonard, Winnie W. Leung, Jordan J. Lucas, Susan A. Ludmann, Blair M. Lyons, Haseeb Malik, Ryan McGregor, Gabe E. Medrash, Sean L. Meharry, Kevin Mitcham, Irina A. Mueller, Timothy L. Murphy-Stevens, Aditya Nath, Angelique M. Nelson, Sandra A. Oluoch, Luana Paleologu, T. Alexander Popiel, Megan M. Riel-Mehan, Brock Roberts, Lisa M. Schaefbauer, Magdalena Schwarzl, Jamie Sherman, Sylvain Slaton, M. Filip Sluzewski, Jacqueline E. Smith, Youngmee Sul, Madison J. Swain-Bowden, W. Joyce Tang, Derek J. Thirstrup, Daniel M. Toloudis, Andrew P. Tucker, Veronica Valencia, Winfried Wiegraebe, Thushara Wijeratna, Ruian Yang, Rebecca J. Zaunbrecher, Ramon Lorenzo D. Labitigan, Adrian L. Sanborn, Graham T. Johnson, Ruwanthi N. Gunawardane, Nathalie Gaudreault, Julie A. Theriot, Susanne M. Rafelski

Publikováno v: Nature. 613:345-354

Understanding how a subset of expressed genes dictates cellular phenotype is a considerable challenge owing to the large numbers of molecules involved, their combinatorics and the plethora of cellular behaviours that they determine1,2. Here we reduce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a684c7c821c5ce222400005b63258558
https://doi.org/10.1038/s41586-022-05563-7

Actin-based protrusions of migrating neutrophils are intrinsically lamellar and facilitate direction changes

Autor: Lillian K Fritz-Laylin, Megan Riel-Mehan, Bi-Chang Chen, Samuel J Lord, Thomas D Goddard, Thomas E Ferrin, Susan M Nicholson-Dykstra, Henry Higgs, Graham T Johnson, Eric Betzig, R Dyche Mullins

Publikováno v: eLife, Vol 6 (2017)

Leukocytes and other amoeboid cells change shape as they move, forming highly dynamic, actin-filled pseudopods. Although we understand much about the architecture and dynamics of thin lamellipodia made by slow-moving cells on flat surfaces, conventio

Externí odkaz: https://doaj.org/article/c16f3220afe84c1989e9c378f662ee27

Does Organelle Shape Matter?: Exploring Patterns in Cell Shape and Structure with High-throughput (HT) Imaging

Autor: Carlos C. Goller, Graham T. Johnson, Kaitlyn Casimo

Publikováno v: CourseSource. 9

Organelle structure has been studied and visualized for decades; however, publicly available databases that use improved high-throughput microscopy of gene-edited cell lines have recently revolutionized the amount and quality of information now avail

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f9eaa8513c25a2d7cacef753b865ecb
https://doi.org/10.24918/cs.2022.3

Visualization Multi-Pipeline for Communicating Biology

Autor: Johannes Sorger, M. Eduard Gröller, Daniel M. Toloudis, Ivan Viola, Graham T. Johnson, Blair M. Lyons, Peter Mindek, David Kouril

Publikováno v: IEEE Transactions on Visualization and Computer Graphics. 24:883-892

We propose a system to facilitate biology communication by developing a pipeline to support the instructional visualization of heterogeneous biological data on heterogeneous user-devices. Discoveries and concepts in biology are typically summarized w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbee78629529476c2ab8f8d40afb960b
https://doi.org/10.1109/tvcg.2017.2744518

Atomistic non-adiabatic dynamics of the LH2 complex with a GPU-accelerated ab initio exciton model

Autor: Simon McIntosh-Smith, Michael B. O'Connor, Aaron Sisto, David R. Glowacki, Clem Stross, Graham T. Johnson, Frederick R. Manby, Marc W. van der Kamp, Todd J. Martínez, Edward G. Hohenstein

Publikováno v: Sisto, A, Van der Kamp, M, Stross, C, O'Connor, M, McIntosh-Smith, S, Johnson, G T, Hohenstein, E G, Manby, F, Glowacki, D & Martinez, T 2017, ' Atomistic non-adiabatic dynamics of the LH2 complex with a GPU-accelerated ab initio exciton model ', Physical Chemistry Chemical Physics, vol. 19, no. 23, pp. 14924-14936 . https://doi.org/10.1039/c7cp00492c

We recently outlined an efficient multi-tiered parallel ab initio excitonic framework that utilizes time dependent density functional theory (TDDFT) to calculate ground and excited state energies and gradients of large supramolecular complexes in ato

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95d6223b56d8b009561142df23fbdcf3
https://doi.org/10.1039/c7cp00492c