Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Graham S. Macaulay"'
Autor:
Kenneth Crook, Richard J. K. Taylor, David Parker, Alison Turner, Terence Seward Baker, Justin J. B. Perry, Timothy J. Norman, Catherine Fiona Catterall, A. Neil Weir, Graham S. Macaulay, Barbara Mason, Michael Anthony William Eaton
Publikováno v:
Angewandte Chemie. 112:4229-4233
Autor:
Michael A. W. Eaton, Terence S. Baker, Catherine F. Catterall, Kenneth Crook, Graham S. Macaulay, Barbara Mason, Timothy J. Norman, David Parker, Justin J. B. Perry, Richard J. Taylor, Alison Turner, A. Neil Weir
Publikováno v:
Angewandte Chemie. 39:4063-4067
Autor:
Joseph F. Hudner, Graham S. Macaulay, Robert A. Stockman, Timothy Harvey, Charles R. White, Roderick John Dorgan, David Lathbury, Lewis Norman John, David O. Morgan, Nigel Hussain, Ian P. Andrews
Publikováno v:
Tetrahedron Letters. 37:4811-4814
A 6-step synthesis of the potent anthelmintic SB-201561 is described. The key stage of the synthesis is a novel Beckmann type oxime fragmentation to give a lactone, followed by a 2-step reassembly of the spirolcetal moiety.
Publikováno v:
Tetrahedron Letters. 35:7665-7668
A short, convenient and inexpensive synthesis of lactone (3) from milbemycin (1) is described. This lactone is a key intermediate in the synthesis of milbemycins.
Autor:
Roderick John Dorgan, Geoffrey Harold Baker, Nigel Hussain, Graham S. Macaulay, David O. Morgan
Publikováno v:
Tetrahedron Letters. 35:2381-2384
The lactone intermediates (3), (4) and (5) are converted via lithium acetylide chemistry to a range of novel C24 and C25-substituted milbemycins. The methdology has been extended to afford milbemycins containing 6,5-spiroacetal units.
Autor:
Roderick John Dorgan, David O. Morgan, Graham S. Macaulay, Geoffrey Harold Baker, Nigel Hussain
Publikováno v:
Tetrahedron Letters. 35:2377-2380
Beckmann fragmentation of 22-oximino milbemycins resulted in the cleavage of the C21–C22 bond to produce a key lactone intermediate which can be used to synthesise new spiroacetals. Cleavage of the C21–O25 bond and recyclisation to produce a fury
Autor:
Roderick John Dorgan, Graham S. Macaulay, David O. Morgan, Geoffrey Harold Baker, Nigel Hussain
Publikováno v:
ChemInform. 25
Beckmann fragmentation of 22-oximino milbemycins resulted in the cleavage of the C21–C22 bond to produce a key lactone intermediate which can be used to synthesise new spiroacetals. Cleavage of the C21–O25 bond and recyclisation to produce a fury
Publikováno v:
ChemInform. 26
Publikováno v:
ChemInform. 19
The synthesis of (E)-2,3,5-trihydroxyphenylprop-1-ene (2) and its 4-chloro-(3), 6-chloro-(4), and 4,6-dichloro- derivatives (5) is described. The routes involve the key intermediates, methyl 2,3,5-tribenzyloxybenzoate (15) and methyl 2,3,5-tribenzylo
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 1. :2209
The synthesis of (E)-2,3,5-trihydroxyphenylprop-1-ene (2) and its 4-chloro-(3), 6-chloro-(4), and 4,6-dichloro- derivatives (5) is described. The routes involve the key intermediates, methyl 2,3,5-tribenzyloxybenzoate (15) and methyl 2,3,5-tribenzylo