Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Graham R. Wallace"'
Autor:
Aidan Anderson, Nada Alfahad, Dulani Wimalachandra, Kaouthar Bouzinab, Paula Rudzinska, Heather Wood, Isabel Fazey, Heping Xu, Timothy J. Lyons, Nicholas M. Barnes, Parth Narendran, Janet M. Lord, Saaeha Rauz, Ian G. Ganley, Tim M. Curtis, Graham R. Wallace, Jose R. Hombrebueno
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract The recovery of mitochondrial quality control (MQC) may bring innovative solutions for neuroprotection, while imposing a significant challenge given the need of holistic approaches to restore mitochondrial dynamics (fusion/fission) and turno
Externí odkaz:
https://doaj.org/article/49bb462680fd472a9c0826d8dc86da53
Autor:
Alberto Recchioni, Maryam Makanvand, Natraj Poonit, Graham R. Wallace, Suzanne Bartington, William Bloss, Saaeha Rauz
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Worldwide lockdown reduced air pollution during the first phase of the COVID-19 pandemic. The relationship between exposure to ambient air pollution, digital display device use and dry eye symptoms amongst patients with severe ocular surface
Externí odkaz:
https://doaj.org/article/b3fad0366204466e89ee5b794a3bb82a
Publikováno v:
Journal of Inflammation, Vol 19, Iss 1, Pp 1-13 (2022)
Abstract Background Behçet’s disease (BD) is a multisystem autoinflammatory disease characterised by mucosal ulceration, ocular, neural, joint and skin inflammation. The cause of BD is not known but there is a strong genetic association with HLA-B
Externí odkaz:
https://doaj.org/article/76bc8b0a7cc540259d0bdaaa7a5faa0b
Autor:
Gibran F. Butt, Ali Hassan, Graham R. Wallace, Shigeru Kinoshita, Sajjad Ahmad, Mayumi Ueta, Saaeha Rauz
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis (SJS/TEN) are part of a disease continuum of vesiculobullous mucocutaneous reactions affecting the skin and mucous membranes including the ocular surface. Manifestations of disease ra
Externí odkaz:
https://doaj.org/article/04415203db674b308306d35f1dba2ca8
Autor:
Alexander Roberts, Lindsay Bentley, Tina Tang, Fay Stewart, Chiara Pallini, Joel Juvvanapudi, Graham R. Wallace, Alison J. Cooper, Aaron Scott, David Thickett, Sebastian T. Lugg, Hollie Bancroft, Bridget Hemming, Charlotte Ferris, Gerald Langman, Andrew Robinson, Joanne Chapman, Babu Naidu, Thomas Pinkney, Graham S. Taylor, Kristian Brock, Zania Stamataki, Catherine A. Brady, S. John Curnow, John Gordon, Omar Qureshi, Nicholas M. Barnes
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Blockade of PD-1/PD-L1 interactions is proving an exciting, durable therapeutic modality in a range of cancers whereby T cells are released from checkpoint inhibition to revive their inherent anti-tumour activity. Here we have studied variou
Externí odkaz:
https://doaj.org/article/17d4c012af55407c96c408b8c553e796
Autor:
Liying Low, Kusy Suleiman, Mohith Shamdas, Kerolos Bassilious, Natraj Poonit, Amanda E. Rossiter, Animesh Acharjee, Nicholas Loman, Philip I. Murray, Graham R. Wallace, Saaeha Rauz
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Mucous Membrane Pemphigoid is an orphan multi-system autoimmune scarring disease involving mucosal sites, including the ocular surface (OcMMP) and gut. Loss of tolerance to epithelial basement membrane proteins and generation of autoreactive T cell a
Externí odkaz:
https://doaj.org/article/79eab56f161c4770964b50becdee9ca6
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Behçet’s disease (BD) is a multisystem autoinflammatory condition characterized by mucosal ulceration, breakdown of immune privilege sites and vasculitis. A genetic basis for BD has been described in genome-wide and validation studies. Similarly,
Externí odkaz:
https://doaj.org/article/cfacd92b687f47608cbe17cb0b8806f2
Autor:
Liying Low, Pablo Fuentes-Utrilla, James Hodson, John D. O’Neil, Amanda E. Rossiter, Ghazala Begum, Kusy Suleiman, Philip I. Murray, Graham R. Wallace, Nicholas J. Loman, Saaeha Rauz, West Midlands Collaborative Ophthalmology Network for Clinical Effectiveness & Research by Trainees (WM CONCERT)
Publikováno v:
PeerJ, Vol 9, p e10778 (2021)
Background Microbial keratitis is a leading cause of preventable blindness worldwide. Conventional sampling and culture techniques are time-consuming, with over 40% of cases being culture-negative. Nanopore sequencing technology is portable and capab
Externí odkaz:
https://doaj.org/article/bfd1b38957d346f69decf2549dcaa889
IL-15 promotes human myogenesis and mitigates the detrimental effects of TNFα on myotube development
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Studies in murine cell lines and in mouse models suggest that IL-15 promotes myogenesis and may protect against the inflammation-mediated skeletal muscle atrophy which occurs in sarcopenia and cachexia. The effects of IL-15 on human skeletal
Externí odkaz:
https://doaj.org/article/d33a33ba397f4c0e9a035dc7e4ebe3f0
Publikováno v:
International Journal of Molecular Sciences, Vol 17, Iss 5, p 729 (2016)
The notion that vitamin D can influence the incidence of cancer arose from epidemiological studies. The major source of vitamin D in the organism is skin production upon exposure to ultra violet-B. The very first observation of an inverse correlation
Externí odkaz:
https://doaj.org/article/c16c739112ef4211bdc074926da05086