Výsledky vyhledávání - "Graham R. Huesmann"

Akademický článek

PROVE: Retrospective, non‐interventional, Phase IV study of perampanel in real‐world clinical care of patients with epilepsy

Autor: Robert T. Wechsler, James Wheless, Muhammad Zafar, Graham R. Huesmann, Marcelo Lancman, Eric Segal, Michael Chez, Sami Aboumatar, Anna Patten, Alejandro Salah, Manoj Malhotra

Publikováno v: Epilepsia Open, Vol 7, Iss 2, Pp 293-305 (2022)

Abstract Objective To assess retention, dosing, efficacy, and safety of perampanel in a large cohort of patients with epilepsy during routine clinical care. Methods PROVE was a retrospective, non‐interventional Phase IV study (NCT03208660). Data we

Externí odkaz: https://doaj.org/article/966bf4f538cd415fbac4e6152240276d

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Akademický článek

Hippocampal stiffness in mesial temporal lobe epilepsy measured with MR elastography: Preliminary comparison with healthy participants

Autor: Graham R. Huesmann, Hillary Schwarb, Daniel R. Smith, Ryan T. Pohlig, Aaron T. Anderson, Matthew D.J. McGarry, Keith D. Paulsen, Tracey Mencio Wszalek, Bradley P. Sutton, Curtis L. Johnson

Publikováno v: NeuroImage: Clinical, Vol 27, Iss , Pp 102313- (2020)

Mesial temporal lobe epilepsy (MTLE) is the most common form of refractory epilepsy. Common imaging biomarkers are often not sensitive enough to identify MTLE sufficiently early to facilitate the greatest benefit from surgical or pharmacological inte

Externí odkaz: https://doaj.org/article/c795050f0ec84e71bd668c881e2559ec

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Pharmacological inhibition of STriatal‐Enriched protein tyrosine Phosphatase by TC‐2153 reduces hippocampal excitability and seizure propensity

Autor: Jennifer M. Walters, Eung Chang Kim, Jiaren Zhang, Han Gil Jeong, Archit Bajaj, Brian C. Baculis, Gregory C. Tracy, Baher Ibrahim, Catherine A. Christian‐Hinman, Daniel A. Llano, Graham R. Huesmann, Hee Jung Chung

Publikováno v: Epilepsia. 63:1211-1224

STriatal-Enriched protein tyrosine Phosphatase (STEP) is a brain-specific tyrosine phosphatase. Membrane-bound STEPAdult male and female C57BL/6J mice received intraperitoneal injection of either vehicle (2.8% dimethylsulfoxide [DMSO] in saline) or T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::686bdcc6a69d139fcd9c1fb5e0c53047
https://doi.org/10.1111/epi.17192

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Standard‐space atlas of the viscoelastic properties of the human brain

Autor: Lucy V Hiscox, Matthew D. J. McGarry, Elijah E. W. Van Houten, Hillary Schwarb, Keith D. Paulsen, Graham R. Huesmann, Ryan T. Pohlig, Charles H. Hillman, Aron K. Barbey, Neal J. Cohen, Neil Roberts, Curtis L. Johnson, Bradley P. Sutton, Agnieszka Z. Burzynska, Arthur F. Kramer

Publikováno v: Hiscox, L V, McGarry, M D J, Schwarb, H, Van Houten, E E W, Pohlig, R T, Roberts, N, Huesmann, G R, Burzynska, A Z, Sutton, B P, Hillman, C H, Kramer, A F, Cohen, N J, Barbey, A K, Paulsen, K D & Johnson, C L 2020, ' Standard-space atlas of the viscoelastic properties of the human brain ', Human Brain Mapping . https://doi.org/10.1002/hbm.25192
Human Brain Mapping

Standard anatomical atlases are common in neuroimaging because they facilitate data analyses and comparisons across subjects and studies. The purpose of this study was to develop a standardized human brain atlas based on the physical mechanical prope

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aa20d98dfd0d512c3c38fbb96535574
https://doi.org/10.1002/hbm.25192

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Hippocampal stiffness in mesial temporal lobe epilepsy measured with MR elastography: Preliminary comparison with healthy participants

Autor: Keith D. Paulsen, Matthew D. J. McGarry, Daniel R. Smith, Graham R. Huesmann, Ryan T. Pohlig, Hillary Schwarb, Aaron T. Anderson, Curtis L. Johnson, Bradley P. Sutton, Tracey Wszalek

Publikováno v: NeuroImage: Clinical, Vol 27, Iss, Pp 102313-(2020)
NeuroImage : Clinical

Highlights • Hippocampal stiffness in MTLE is measured with magnetic resonance elastography. • The epileptogenic hippocampus is stiffer than non-epileptogenic hippocampus in MTLE. • Hippocampal stiffness ratio is higher in MTLE patients than in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58f1641c1a4d953a06b1fb88e3bbce7d
http://www.sciencedirect.com/science/article/pii/S2213158220301509

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Viscoelasticity of subcortical gray matter structures

Autor: Matthew D. J. McGarry, Hillary Schwarb, Neal J. Cohen, Curtis L. Johnson, Aaron T. Anderson, Bradley P. Sutton, Graham R. Huesmann

Publikováno v: Human Brain Mapping. 37:4221-4233

Viscoelastic mechanical properties of the brain assessed with magnetic resonance elastography (MRE) are sensitive measures of microstructural tissue health in neurodegenerative conditions. Recent efforts have targeted measurements localized to specif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ceca6684e91790a5665f86948743624d
https://doi.org/10.1002/hbm.23314

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Neuropeptide stimulation of the nitric oxide signaling pathway in Drosophila melanogaster Malpighian tubules

Autor: S. H. P. Maddrell, Julian A. T. Dow, Nathan J. Tublitz, Eric J. Stewart, Graham R. Huesmann, Shireen A. Davies, Nicholas J.V. Skaer

Publikováno v: American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 273:R823-R827

Activation of the nitric oxide (NO) and guanosine 3', 5'-cyclic monophosphate (cGMP) signaling pathway stimulates fluid secretion by the Drosophila melanogaster Malpighian tubule. The neuropeptide cardioacceleratory peptide 2b (CAP2b) has been previo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18363c11c1feb91f487c18e962838e96
https://doi.org/10.1152/ajpregu.1997.273.2.r823

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Giant cell arteritis causing symmetric bilateral posterior circulation infarcts

Autor: Misha L. Pless, Devin D Mackay, Graham R. Huesmann, Roseann I. Wu, James R. Stone

Publikováno v: Journal of clinical rheumatology : practical reports on rheumaticmusculoskeletal diseases. 19(7)

An 82-year-old woman presented with bilateral, symmetric posterior circulation infarctions secondary to giant cell arteritis (GCA). Her atypical clinical presentation included a lack of headache and fever, but she exhibited signs of systemic illness

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51a62b8a3db6f14c3a5d0628ff56c4fe
https://pubmed.ncbi.nlm.nih.gov/24048110

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CAP2b, a cardioacceleratory peptide, is present in Drosophila and stimulates tubule fluid secretion via cGMP

Autor: Julian A. T. Dow, N. J. Tublitz, N. J. V. Skaer, Shireen A. Davies, Graham R. Huesmann, Michael P. O'Donnell, S. H. P. Maddrell

Publikováno v: American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 269:R1321-R1326

A cardioacceleratory peptide, CAP2b, identified originally in the lepidopteran Manduca sexta, stimulates fluid secretion by Malpighian tubules of the dipteran Drosophila melanogaster. High-performance liquid chromatography analyses of adult D. melano

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5988ad20a7972155abc5d231ba662b3f
https://doi.org/10.1152/ajpregu.1995.269.6.r1321

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