Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Graham R. Elliott"'
Autor:
Karin Loser, Graham R. Elliott, Carlo Sternemann, Thomas A. Luger, Matteo Auriemma, Lars Klenner, C. Baumann, Nadine Mykicki, Christoph Abels, Michael Soeberdt
Publikováno v:
Experimental Dermatology. 26:328-334
Psoriasis is a chronic inflammatory disease appearing as scaly erythematous cutaneous lesions, which are characterized by parakeratosis and acanthosis as well as the infiltration of immune cells, such as T helper-1 and T helper-17 cells. Here, we dem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8752b8be3c99270ed215d94d7a45b163
https://doi.org/10.1111/exd.13145
https://doi.org/10.1111/exd.13145
Publikováno v:
Mediators of Inflammation, Vol 2, Iss 7, Pp S57-S62 (1993)
THE acyl carrier coenzyme A (CoA) is involved in fatty acid metabolism. The carnitine/CoA ratio is of particular importance in regulating the transport of long-chain fatty acids into mitochondria for oxidation. Also CoA has a role in the formation an
Externí odkaz:
https://doaj.org/article/ae76811bea53452d872bf713279dc36f
Autor:
Michael Soeberdt, Graham R. Elliott, Tobias Lotts, Christoph Abels, Sonja Ständer, Raymond Vanwersch, Dieter Metze
Publikováno v:
Journal of dermatological science. 84(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68cb31114f3da1ba85f0ccb5e6c880ee
https://pubmed.ncbi.nlm.nih.gov/27665389
https://pubmed.ncbi.nlm.nih.gov/27665389
Publikováno v:
Experimental dermatology, 15(6), 432-440. Wiley-Blackwell
Skin irritants and contact allergens reduce the number of Langerhans cells (LCs). It has been assumed that this reduction is due their migration to the draining lymph node (LN) for initiating immune sensitization in a host. Skin irritation, however,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3415faab529a2d7a0bd30c9252a96109
https://doi.org/10.1111/j.0906-6705.2006.00420.x
https://doi.org/10.1111/j.0906-6705.2006.00420.x
Publikováno v:
Toxicology in vitro, 18(5), 681-690. Elsevier Limited
The human organotypic skin explant culture (hOSEC) model is a promising alternative in vitro model for screening contact allergens. In this model, the chemical-induced migration of Langerhans cells (LCs) out of the epidermis, evaluated after a 24-h e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa78f1643f77bc5a5b7ce722d1d1100c
https://doi.org/10.1016/j.tiv.2004.03.007
https://doi.org/10.1016/j.tiv.2004.03.007
Autor:
T. Graham R. Elliott, Johannes J.M. van de Sandt, Wim J.A. Meuling, Nicole H. P. Cnubben, Betty C. Hakkert
Publikováno v:
Toxicological Sciences. 58:15-22
In vitro and in vivo skin absorption of the pesticide propoxur (2-isopropoxyphenyl N-methyl carbamate, commercially Baygon(TM) and Unden(TM); log Po/w 1.56, MW 209.2) was investigated. In vivo studies were performed in rats and human volunteers, appl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1944c15e73ee996dd531a11f0cc7c251
https://doi.org/10.1093/toxsci/58.1.15
https://doi.org/10.1093/toxsci/58.1.15
Publikováno v:
Alternatives to Laboratory Animals. 28:279-292
We describe a new alternative method for screening for skin irritants by using fresh intact porcine skin biopsies. Test chemicals were applied to the epidermis of the biopsies, which were then incubated for different times in tissue culture medium at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfc3341af5dc7bc850c39c90960bdc1e
https://doi.org/10.1177/026119290002800206
https://doi.org/10.1177/026119290002800206
Publikováno v:
British Journal of Nutrition, 72(5), 785-793. Cambridge University Press
The effect of short- and long-term feeding with L-carnitine, L-acetyl carnitine and L-propionyl carnitine on the production of eicosanoids frontin vitrostimulated carrageenan-induced rat peritoneal macrophages was investigated. Both young (4 weeks) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a81771c6d5aaef85fe48779fe5d45568
http://www.scopus.com/inward/record.url?scp=0028114424&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=0028114424&partnerID=8YFLogxK
Publikováno v:
Mediators of Inflammation, 2(7), S57-S62. Hindawi Publishing Corporation
Mediators of Inflammation
Mediators of Inflammation, Vol 2, Iss 7, Pp S57-S62 (1993)
Mediators of Inflammation
Mediators of Inflammation, Vol 2, Iss 7, Pp S57-S62 (1993)
THE acyl carrier coenzyme A (CoA) is involved in fatty acid metabolism. The carnitine/CoA ratio is of particular importance in regulating the transport of long-chain fatty acids into mitochondria for oxidation. Also CoA has a role in the formation an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e9804644447373deca663a4e85f141b
https://doi.org/10.1155/S0962935193000778
https://doi.org/10.1155/S0962935193000778
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 27:71-77
To overcome most of the disadvantages of current models to investigate percutaneous penetration of drugs or toxic substances, a model is proposed here based on the isolated pig ear, which is obtained at the slaughterhouse, and perfused with oxygenate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c7f04183159e326838ec25b26f081eb
https://doi.org/10.1016/1056-8719(92)90024-u
https://doi.org/10.1016/1056-8719(92)90024-u