Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Graham P. Wright"'
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Adoptive therapy with polyclonal regulatory T cells (Tregs) has shown efficacy in suppressing detrimental immune responses in experimental models of autoimmunity and transplantation. The lack of specificity is a potential limitation of Treg therapy,
Externí odkaz:
https://doaj.org/article/0aa8969e46494f15b6fff64683293c8a
Autor:
Calder D. Sheagren, Tianle Cao, Jaykumar H. Patel, Zihao Chen, Hsu-Lei Lee, Nan Wang, Anthony G. Christodoulou, Graham A. Wright
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
T1 mapping is becoming a staple magnetic resonance imaging method for diagnosing myocardial diseases such as ischemic cardiomyopathy, hypertrophic cardiomyopathy, myocarditis, and more. Clinically, most T1 mapping sequences acquire a single slice at
Externí odkaz:
https://doaj.org/article/e1dd9be4d5c24c3093a312ed442a596f
Autor:
Debbie X. E. Lim, Toby Richards, Muholan Kanapathy, Thankiah Sudhaharan, Graham D. Wright, Anthony R. J. Phillips, David L. Becker
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract High prevalence of non-healing chronic wounds contributes to a huge healthcare burden across the world. Early treatment interventions for non-healing wounds are vital. It was previously shown that accumulation of 15% or more of senescent cel
Externí odkaz:
https://doaj.org/article/0c085bdde7cd4c53b87a024a620457a5
Autor:
Marie Strickland, Salanne Lee, Shi Yong Neo, Akhila Balachander, Ivy Low, Seri Mustafah, Wah Ing Goh, Graham D. Wright, Anis Larbi, Sylvia L. F. Pender
Publikováno v:
Biology, Vol 12, Iss 4, p 597 (2023)
Human ageing is accompanied by poor responses to infection and decreased vaccine efficacy. While the causes of this can be attributed to defects in the immune system that increase with age, it is unknown whether mitochondrial dysfunction may also con
Externí odkaz:
https://doaj.org/article/f008b7fea35744af944fc354145a444d
Autor:
Emelyne Teo, Soon Yew John Lim, Sheng Fong, Anis Larbi, Graham D. Wright, Nicholas Tolwinski, Jan Gruber
Publikováno v:
Translational Medicine of Aging, Vol 4, Iss , Pp 11-21 (2020)
Alzheimer’s disease (AD), characterized by memory loss and cognitive decline, is one of the diseases with the highest attrition rate in drug development. As with other neurodegenerative diseases, AD manifests on several scales (molecular, cellular
Externí odkaz:
https://doaj.org/article/2c7e77291e524e2eb5996ee15a6c1919
Publikováno v:
Journal of Imaging, Vol 8, Iss 7, p 203 (2022)
We conducted a systematic review of recent literature to understand the current challenges in the use of optical see-through head-mounted displays (OST-HMDs) for augmented reality (AR) assisted surgery. Using Google Scholar, 57 relevant articles from
Externí odkaz:
https://doaj.org/article/c7e3a5150bcf4da4ae813326bebb066f
Autor:
Philippa R. P. Krahn, Sheldon M. Singh, Venkat Ramanan, Labonny Biswas, Nicolas Yak, Kevan J. T. Anderson, Jennifer Barry, Mihaela Pop, Graham A. Wright
Publikováno v:
Journal of Cardiovascular Magnetic Resonance, Vol 20, Iss 1, Pp 1-12 (2018)
Abstract Background Radiofrequency (RF) ablation has become a mainstay of treatment for ventricular tachycardia, yet adequate lesion formation remains challenging. This study aims to comprehensively describe the composition and evolution of acute lef
Externí odkaz:
https://doaj.org/article/51e5f73d234f4dcf85fb34e6d1f5be8a
Autor:
Olga Biskou, Victor Casanova, Kirsty M Hooper, Sadie Kemp, Graham P Wright, Jack Satsangi, Peter G Barlow, Craig Stevens
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0209665 (2019)
The cytoskeletal protein vimentin plays a key role in positioning of organelles within the cytosol and has been linked to the regulation of numerous cellular processes including autophagy, however, how vimentin regulates autophagy remains relatively
Externí odkaz:
https://doaj.org/article/83911f38ecef4d5c8d5d25e5b1a2fb50
Autor:
Idan Roifman, Harindra C. Wijeysundera, Peter C. Austin, Mohammad R. Rezai, Graham A. Wright, Jack V. Tu
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 7 (2017)
BackgroundThe optimal initial noninvasive diagnostic testing strategy for stable coronary artery disease (CAD) is unknown. Although American guidelines recommend an exercise stress test as the first‐line test, European guidelines suggest that stres
Externí odkaz:
https://doaj.org/article/27cf55103d0d4a5cb902b4f74437f736
Autor:
Alexandre Chojnowski, Peh Fern Ong, Esther SM Wong, John SY Lim, Rafidah A Mutalif, Raju Navasankari, Bamaprasad Dutta, Henry Yang, Yi Y Liow, Siu K Sze, Thomas Boudier, Graham D Wright, Alan Colman, Brian Burke, Colin L Stewart, Oliver Dreesen
Publikováno v:
eLife, Vol 4 (2015)
Hutchinson-Gilford progeria (HGPS) is a premature ageing syndrome caused by a mutation in LMNA, resulting in a truncated form of lamin A called progerin. Progerin triggers loss of the heterochromatic marker H3K27me3, and premature senescence, which i
Externí odkaz:
https://doaj.org/article/7048e43aee15493aa8dd8effd02435c3