Zobrazeno 1 - 10
of 234
pro vyhledávání: '"Graham P Leese"'
Autor:
Naveed Sattar, Sarah Wild, David McAllister, Katherine Hughes, Ewan R Pearson, Helen M Colhoun, Paul M McKeigue, Sam Philip, John Petrie, John McKnight, Robert Lindsay, Graham P Leese, Anna Barnett, Stuart J. McGurnaghan, Luke A. K. Blackbourn, Thomas M. Caparrotta, Joseph Mellor, Andy Collier
Publikováno v:
BMJ Open, Vol 12, Iss 10 (2022)
Purpose The Scottish Diabetes Research Network (SDRN)-diabetes research platform was established to combine disparate electronic health record data into research-ready linked datasets for diabetes research in Scotland. The resultant cohort, ‘The SD
Externí odkaz:
https://doaj.org/article/529d779545bb437e9bb807e3a690f58c
Autor:
David Weller, Francesca M Chappell, Angela Martin, Margaret Horne, Graham P Leese, Fay Crawford, Andrew J M Boulton, Caroline Abbott, Aristidis Veves
Publikováno v:
BMJ Open Diabetes Research & Care, Vol 9, Iss 1 (2021)
Introduction The aim of the study was to develop and validate a clinical prediction rule (CPR) for foot ulceration in people with diabetes.Research design and methods Development of a CPR using individual participant data from four international coho
Externí odkaz:
https://doaj.org/article/1265fe7426da4b6384496e5944f04df2
Autor:
Samira Bell, Bassam Farran, Stuart McGurnaghan, Rory J. McCrimmon, Graham P Leese, John R Petrie, Paul McKeigue, Naveed Sattar, Sarah Wild, John McKnight, Robert Lindsay, Helen M. Colhoun, Helen Looker
Publikováno v:
BMC Nephrology, Vol 18, Iss 1, Pp 1-8 (2017)
Abstract Background Whether metformin precipitates lactic acidosis in patients with chronic kidney disease (CKD) remains under debate. We examined whether metformin use was associated with an increased risk of acute kidney injury (AKI) as a proxy for
Externí odkaz:
https://doaj.org/article/82e6120d7ce74724820ef0a5563b18b5
Autor:
Andreas Ochs, Stuart McGurnaghan, Mike W Black, Graham P Leese, Sam Philip, Naveed Sattar, Caroline Styles, Sarah H Wild, Paul M McKeigue, Helen M Colhoun, Scottish Diabetes Research Network Epidemiology Group and the Diabetic Retinopathy Screening Collaborative
Publikováno v:
PLoS Medicine, Vol 16, Iss 10, p e1002945 (2019)
BACKGROUND:National guidelines in most countries set screening intervals for diabetic retinopathy (DR) that are insufficiently informed by contemporary incidence rates. This has unspecified implications for interval disease risks (IDs) of referable D
Externí odkaz:
https://doaj.org/article/50276b4bab2d4077846c04a2ed51a1c0
Publikováno v:
Endocrine Connections, Vol 6, Iss 8, Pp 580-588 (2007)
Purpose: High serum prolactin concentrations have been associated with adverse health outcomes in some but not all studies. This study aimed to examine the morbidity and all-cause mortality associated with hyperprolactinaemia. Methods: A population-
Externí odkaz:
https://doaj.org/article/becb78689a7b450091dda29a9863f587
Autor:
Shona J Livingstone, Helen C Looker, Eleanor J Hothersall, Sarah H Wild, Robert S Lindsay, John Chalmers, Stephen Cleland, Graham P Leese, John McKnight, Andrew D Morris, Donald W M Pearson, Norman R Peden, John R Petrie, Sam Philip, Naveed Sattar, Frank Sullivan, Helen M Colhoun
Publikováno v:
PLoS Medicine, Vol 9, Iss 10, p e1001321 (2012)
BackgroundRandomized controlled trials have shown the importance of tight glucose control in type 1 diabetes (T1DM), but few recent studies have evaluated the risk of cardiovascular disease (CVD) and all-cause mortality among adults with T1DM. We eva
Externí odkaz:
https://doaj.org/article/23620e1bdcf04ea08d5b742db91e53d6
Autor:
Aravind Lathika Rajendrakumar, Simona M. Hapca, Anand Thakarakkattil Narayanan Nair, Yu Huang, Mehul Kumar Chourasia, Ryan Shun-Yuen Kwan, Charvi Nangia, Moneeza K. Siddiqui, Prathiba Vijayaraghavan, Shona Z. Matthew, Graham P. Leese, Viswanathan Mohan, Ewan R. Pearson, Alexander S. F. Doney, Colin N. A. Palmer
Publikováno v:
BMC Medicine, Vol 21, Iss 1, Pp 1-11 (2023)
Abstract Background Diabetic retinopathy (DR) is a major sight-threatening microvascular complication in individuals with diabetes. Systemic inflammation combined with oxidative stress is thought to capture most of the complexities involved in the pa
Externí odkaz:
https://doaj.org/article/f99aa2ef079f42f481821a664ed074e3
Autor:
Alexander S. F. Doney, Aditya Nar, Yu Huang, Emanuele Trucco, Tom MacGillivray, Peter Connelly, Graham P. Leese, Gareth J. McKay, on behalf of the INSPIRED consortium
Publikováno v:
Frontiers in Digital Health, Vol 4 (2022)
ObjectivePatients with diabetes have an increased risk of dementia. Improved prediction of dementia is an important goal in developing future prevention strategies. Diabetic retinopathy screening (DRS) photographs may be a convenient source of imagin
Externí odkaz:
https://doaj.org/article/ca6d477f298741fe8dbe04650ae16dc0
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism.
Context Previous studies, including our own, have demonstrated a highly variable incidence of primary hyperparathyroidism (PHPT) from year to year. Objective We planned to provide a current estimate of the incidence and prevalence of PHPT in a commun
Autor:
Sonia Kaniuka-Jakubowska, Miles J Levy, Aparna Pal, Dayakshi Abeyaratne, William M Drake, Nikolaos Kyriakakis, Robert D Murray, Steve M Orme, Shailesh Gohil, Antonia Brooke, Graham P Leese, Márta Korbonits, John AH Wass
Publikováno v:
Endocrine-Related Cancer. 30
The aim of this study is to characterise somatostatin analogue-responsive headache in acromegaly, hitherto not systematically documented in a significant cohort. Using the UK pituitary network, we have clinically characterised a cohort of 18 patients