Zobrazeno 1 - 10
of 234
pro vyhledávání: '"Graham P, Leese"'
Autor:
Aravind Lathika Rajendrakumar, Simona M. Hapca, Anand Thakarakkattil Narayanan Nair, Yu Huang, Mehul Kumar Chourasia, Ryan Shun-Yuen Kwan, Charvi Nangia, Moneeza K. Siddiqui, Prathiba Vijayaraghavan, Shona Z. Matthew, Graham P. Leese, Viswanathan Mohan, Ewan R. Pearson, Alexander S. F. Doney, Colin N. A. Palmer
Publikováno v:
BMC Medicine, Vol 21, Iss 1, Pp 1-11 (2023)
Abstract Background Diabetic retinopathy (DR) is a major sight-threatening microvascular complication in individuals with diabetes. Systemic inflammation combined with oxidative stress is thought to capture most of the complexities involved in the pa
Externí odkaz:
https://doaj.org/article/f99aa2ef079f42f481821a664ed074e3
Autor:
Naveed Sattar, Sarah Wild, David McAllister, Katherine Hughes, Ewan R Pearson, Helen M Colhoun, Paul M McKeigue, Sam Philip, John Petrie, John McKnight, Robert Lindsay, Graham P Leese, Anna Barnett, Stuart J. McGurnaghan, Luke A. K. Blackbourn, Thomas M. Caparrotta, Joseph Mellor, Andy Collier
Publikováno v:
BMJ Open, Vol 12, Iss 10 (2022)
Purpose The Scottish Diabetes Research Network (SDRN)-diabetes research platform was established to combine disparate electronic health record data into research-ready linked datasets for diabetes research in Scotland. The resultant cohort, ‘The SD
Externí odkaz:
https://doaj.org/article/529d779545bb437e9bb807e3a690f58c
Autor:
Alexander S. F. Doney, Aditya Nar, Yu Huang, Emanuele Trucco, Tom MacGillivray, Peter Connelly, Graham P. Leese, Gareth J. McKay, on behalf of the INSPIRED consortium
Publikováno v:
Frontiers in Digital Health, Vol 4 (2022)
ObjectivePatients with diabetes have an increased risk of dementia. Improved prediction of dementia is an important goal in developing future prevention strategies. Diabetic retinopathy screening (DRS) photographs may be a convenient source of imagin
Externí odkaz:
https://doaj.org/article/ca6d477f298741fe8dbe04650ae16dc0
Autor:
Graham P. Leese
Publikováno v:
Thyroid Research, Vol 13, Iss 1, Pp 1-5 (2020)
Abstract The new NICE guidelines on thyroid disease and its management do not recommend the routine use of liothyronine, but do not completely rule it out either. Guidelines from the British and European Thyroid Associations are open to a “trial of
Externí odkaz:
https://doaj.org/article/0422af31c44d4ca08ac643adb2f5b1fc
Autor:
Bernardo Meza-Torres, Scott G. Cunningham, Christian Heiss, Mark Joy, Michael Feher, Graham P. Leese, Simon de Lusignan, Fabrizio Carinci
Publikováno v:
Journal of Diabetes Research, Vol 2022 (2022)
Aims. To compare different packages of care across care providers in Scotland on foot-related outcomes. Methods. A retrospective cohort study with primary and secondary care electronic health records from the Scottish Diabetes Registry, including 6,8
Externí odkaz:
https://doaj.org/article/e2a3e913fa4f426a91370156e850dcd5
Autor:
Enrique Soto-Pedre, Moneeza K. Siddiqui, Cyrielle Maroteau, Adem Y. Dawed, Alex S. Doney, Colin N. A. Palmer, Ewan R. Pearson, Graham P. Leese
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
AimsAtrial fibrillation (AF) is a risk for patients receiving thyroid hormone replacement therapy. No published work has focused on pharmacogenetics relevant to thyroid dysfunction and AF risk. We aimed to assess the effect of L-thyroxine on AF risk
Externí odkaz:
https://doaj.org/article/5c6ce436a3ce49038c91e9faed6d699c
Autor:
David Weller, Francesca M Chappell, Richard D Riley, Angela Martin, Matilde Monteiro-Soares, Margaret Horne, Graham P Leese, Fay Crawford, Andrew J M Boulton, Caroline Abbott, Aristidis Veves
Publikováno v:
BMJ Open Diabetes Research & Care, Vol 9, Iss 1 (2021)
Introduction The aim of the study was to develop and validate a clinical prediction rule (CPR) for foot ulceration in people with diabetes.Research design and methods Development of a CPR using individual participant data from four international coho
Externí odkaz:
https://doaj.org/article/1265fe7426da4b6384496e5944f04df2
Autor:
Huan Wang, Peter T. Donnan, Callum J. Leese, Edward Duncan, David Fitzpatrick, Brian M. Frier, Graham P. Leese
Publikováno v:
Clinical Diabetes and Endocrinology, Vol 3, Iss 1, Pp 1-8 (2017)
Abstract Background Almost 20 years ago, the frequencies of severe hypoglycemia requiring emergency medical treatment were reported in people with types 1 and 2 diabetes in the Tayside region of Scotland. With subsequent improvements in the treatment
Externí odkaz:
https://doaj.org/article/4f25260d06a64a1ebb15330370cf78b1
Autor:
Samira Bell, Bassam Farran, Stuart McGurnaghan, Rory J. McCrimmon, Graham P Leese, John R Petrie, Paul McKeigue, Naveed Sattar, Sarah Wild, John McKnight, Robert Lindsay, Helen M. Colhoun, Helen Looker
Publikováno v:
BMC Nephrology, Vol 18, Iss 1, Pp 1-8 (2017)
Abstract Background Whether metformin precipitates lactic acidosis in patients with chronic kidney disease (CKD) remains under debate. We examined whether metformin use was associated with an increased risk of acute kidney injury (AKI) as a proxy for
Externí odkaz:
https://doaj.org/article/82e6120d7ce74724820ef0a5563b18b5
Autor:
Andreas Ochs, Stuart McGurnaghan, Mike W Black, Graham P Leese, Sam Philip, Naveed Sattar, Caroline Styles, Sarah H Wild, Paul M McKeigue, Helen M Colhoun, Scottish Diabetes Research Network Epidemiology Group and the Diabetic Retinopathy Screening Collaborative
Publikováno v:
PLoS Medicine, Vol 16, Iss 10, p e1002945 (2019)
BACKGROUND:National guidelines in most countries set screening intervals for diabetic retinopathy (DR) that are insufficiently informed by contemporary incidence rates. This has unspecified implications for interval disease risks (IDs) of referable D
Externí odkaz:
https://doaj.org/article/50276b4bab2d4077846c04a2ed51a1c0