Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Graham P, Feeney"'
Autor:
Barbara Płytycz, A John Morgan, Stephen R StĂźrzenbaum, Michael O' Reilly, Graham P Feeney, Justyna Cholewa
Publikováno v:
Folia Histochemica et Cytobiologica, Vol 44, Iss 1, Pp 65-71 (2006)
Immunocompetent cells of earthworms, coelomocytes, comprise adherent amoebocytes and granular eleocytes (chloragocytes). Both cell populations can be expelled via dorsal pores of adult earthworms by exposure to an electric current (4.5 V) for 1 min.
Externí odkaz:
https://doaj.org/article/cacd61e61da8449b8b65b4bc3ba6800d
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1732:88-95
In contrast to mammals, zinc transporter genes remain largely uncharacterised in teleosts. Teleost zinc transporter genes were data-mined and phylogenetically assigned to mammalian orthologues. For the first time in animals, the tissue-distribution a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b526ab7bbcc1ba54a88332484d743aea
https://doi.org/10.1016/j.bbaexp.2005.12.002
https://doi.org/10.1016/j.bbaexp.2005.12.002
Autor:
Graham P. Feeney, Paul Smith, R.J. Erringtonb, Michael J. Chappell, M.J. Chapman, Neil D. Evans, Mike Shelley, Keith R. Godfrey
Publikováno v:
IFAC Proceedings Volumes. 36:403-408
In this paper, a compartmental model is proposed for describing the in vitro kinetics of the anti-cancer agent topotecan following administration into a culture medium containing human lymphoma cells in suspension. The model extends one previously pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88c347fe1474f7270fe05d4bc0d7c75d
https://doi.org/10.1016/s1474-6670(17)33537-1
https://doi.org/10.1016/s1474-6670(17)33537-1
Autor:
Graham P. Feeney, Rachel J. Errington, Marie Wiltshire, Paul Smith, Nuria Marquez, Sally Claire Chappell
Publikováno v:
British Journal of Cancer
The anticancer agent topotecan is considered to be S-phase specific. This implies that cancer cells that are not actively replicating DNA could resist the effects of the drug. The cycle specificity of topotecan action was investigated in MCF-7 cells,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dcbb08906c50edba66773832305ba0a
https://doi.org/10.1038/sj.bjc.6600889
https://doi.org/10.1038/sj.bjc.6600889
Autor:
Mark Worwood, Graham P. Feeney
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1538(2-3):242-251
In order to measure the effects of HFE (haemochromatosis) upon iron uptake, stable expression of wild-type and C282Y, H63D and S65C mutant HFE cDNA was established in HEK 293 cells. Control cells were transfected with empty vector. Expression of HFE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0df16307505e2a91e246df420794e236
Publikováno v:
Metallomics
Global transcriptomic analysis, non-invasive real-time flux, nutritional profiling and metallomics reveal cell-centric response to zinc supplementation/depletion in zebrafish uptake epithelia.
Much remains to be understood about systemic regulat
Much remains to be understood about systemic regulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae246b196f7017af1b79ebe5fa6e3546
https://pubmed.ncbi.nlm.nih.gov/24301558
https://pubmed.ncbi.nlm.nih.gov/24301558
Autor:
Dongling Zheng, Peter Kille, Graham P Feeney, Phil Cunningham, Richard D Handy, Christer Hogstrand
Publikováno v:
BMC Genomics, Vol 11, Iss 1, p 548 (2010)
BMC Genomics
BMC Genomics
Background Zinc deficiency is detrimental to organisms, highlighting its role as an essential micronutrient contributing to numerous biological processes. To investigate the underlying molecular events invoked by zinc depletion we performed a tempora
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10c8c835d34db5e409b3b2b6704cd357
http://www.biomedcentral.com/1471-2164/11/548
http://www.biomedcentral.com/1471-2164/11/548
Autor:
Christer Hogstrand, Richard D. Handy, Philip Cunningham, Graham P. Feeney, Peter Kille, Dongling Zheng
Publikováno v:
BMC Genomics
BMC Genomics, Vol 11, Iss 1, p 553 (2010)
BMC Genomics, Vol 11, Iss 1, p 553 (2010)
Background Dietary zinc supplementation may help to promote growth, boost the immune system, protect against diabetes, and aid recovery from diarrhoea. We exploited the zebrafish (Danio rerio) gill as a unique vertebrate ion transporting epithelium m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::135bbe4dfcb21de2cb2843d06eba09b9
https://pubmed.ncbi.nlm.nih.gov/20937081
https://pubmed.ncbi.nlm.nih.gov/20937081
Autor:
Marie Wiltshire, Lee Campbell, Graham P. Feeney, Rachel J. Errington, Paul J. Smith, Emeline Furon, R. D. Snyder
Publikováno v:
Cytometry. Part A : the journal of the International Society for Analytical Cytology. 75(11)
Drug resistant tumor “side-populations,” enriched in cancer stem cells and identified by reduced accumulation of Hoechst 33342 under ABCG2-mediated efflux, may compromise therapeutic outcome. Side-population cells have predicted resistance to min
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3f71181f648a6b93b05a0f7327957a8
https://pubmed.ncbi.nlm.nih.gov/19802874
https://pubmed.ncbi.nlm.nih.gov/19802874
Publikováno v:
Physiological genomics. 34(2)
Resolving the mechanisms underlying the temporal and spatial profile of zinc transporter expression in response to zinc availability is key to understanding zinc homeostasis. The mRNA expression of seven zinc transporters was studied in zebrafish gil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05fc258349b9aa0de36d6e6668c7542c
https://pubmed.ncbi.nlm.nih.gov/18477665
https://pubmed.ncbi.nlm.nih.gov/18477665