Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Graham Niepel"'
Autor:
R. W. Langley, Janek Vilisaar, Graham Niepel, Christopher M. Bradshaw, Rashid H. Bibani, Elemer Szabadi, Cris S. Constantinescu
Publikováno v:
Neuropharmacology. 64:380-388
Multiple sclerosis (MS) is a multifocal demyelinating disease of the central nervous system, leading to chronic disability. Fatigue is a common and distressing symptom of MS which is unrelated to its clinical form, stage of development, the degree of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61e493fc4c8c84cb93c41fc2b249fe75
https://doi.org/10.1016/j.neuropharm.2012.06.036
https://doi.org/10.1016/j.neuropharm.2012.06.036
Publikováno v:
Journal of Neurology, Neurosurgery & Psychiatry. 88:A14.4-A15
Background The extreme delta brush (EDB) pattern is considered pathognomonic of anti-NMDAR encephalitis. Ketamine, a NMDA receptor antagonist has induced a similar pattern on EEG when used as an anaesthetic or for refractory epilepsy. We present a ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41a91825f1c4753c2e535d8595f5a3f7
https://doi.org/10.1136/jnnp-2017-abn.45
https://doi.org/10.1136/jnnp-2017-abn.45
Publikováno v:
Multiple Sclerosis Journal. 15:1442-1449
Recent work in multiple sclerosis, focusing on neuropathological abnormalities, found a frequent and severe hypothalamic involvement. The possible clinical implications are disturbances in sleep and sexual activity, depression, memory impairment and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81e4732277f7c00464e5f6a783c1bc4c
https://doi.org/10.1177/1352458509350306
https://doi.org/10.1177/1352458509350306
Publikováno v:
Journal of the Neurological Sciences. 237:13-19
Specific neurological impairments in multiple sclerosis (MS) are dependent on the pathology in clinically eloquent areas of the central nervous system. We aimed to use diffusion tensor fiber tracking to identify the pyramidal tracts and corpus callos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2d587aae98fd06a0f11c8010dd395fe
https://doi.org/10.1016/j.jns.2005.04.019
https://doi.org/10.1016/j.jns.2005.04.019
Autor:
Laura Edwards, Geoffrey W. Bennett, Christopher R. Tench, Cris S. Constantinescu, Angela J. Fahey, Mohammad A. Ghatei, S. Harikrishnan, Aisha Judd, Michael Patterson, Graham Niepel, Manjit Braitch
Publikováno v:
Journal of the neurological sciences. 307(1-2)
Background Fatigue and sleep disturbance are common features of multiple sclerosis (MS). Our objectives were to determine cerebrospinal fluid levels of orexin A (hypocretin-1), a hypothalamic peptide involved in sleep, in patients with MS, and correl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::970b4aad099b5992e978586ff2a4a092
https://pubmed.ncbi.nlm.nih.gov/21605873
https://pubmed.ncbi.nlm.nih.gov/21605873
Publikováno v:
Archives of neurology. 65(5)
Objective To determine cerebrospinal fluid levels of osteopontin (OPN), a proinflammatory cytokine that was found to be overexpressed in multiple sclerosis lesions and increased in plasma during relapses and in secondary progressive multiple sclerosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe6a44d68e7154ee9ba6a677d1fd8d2b
https://pubmed.ncbi.nlm.nih.gov/18474739
https://pubmed.ncbi.nlm.nih.gov/18474739
Autor:
Christopher R. Tench, Dorothee P. Auer, Nikos Evangelou, Paul S. Morgan, Cris S. Constantinescu, Graham Niepel
Publikováno v:
Journal of neurology. 253(7)
Fatigue in multiple sclerosis (MS) occurs commonly, sometimes as the earliest symptom. Some MS patients consider fatigue to be their most troublesome complaint, and it has been shown to be an independent predictor of impaired quality of life. Several
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05c0ff1b8666c926f80131f8e9540db9
https://pubmed.ncbi.nlm.nih.gov/16525881
https://pubmed.ncbi.nlm.nih.gov/16525881
Publikováno v:
Multiple sclerosis (Houndmills, Basingstoke, England). 11(4)
It has been suggested that multiple sclerosis (MS) patients with positive anticardiolipin antibodies (ACLA) have some atypical features, including absent oligoclonal bands (OCB) in the cerebrospinal fluid (CSF). Our aim was to compare the frequencies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57155c976e108610e77115413d2d24f0
https://pubmed.ncbi.nlm.nih.gov/16042217
https://pubmed.ncbi.nlm.nih.gov/16042217