Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Graham McIlroy"'
Autor:
Graham McIlroy, Siân Lax, Charlotte Gaskell, Aimee Jackson, Malcolm Rhodes, Tania Seale, Sonia Fox, Lousie Hopkins, Jessica Okosun, Sally F. Barrington, Ingo Ringshausen, Alan G. Ramsay, Maria Calaminici, Kim Linton, Mark Bishton
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Relapsed or refractory follicular lymphoma (rrFL) is an incurable disease associated with shorter remissions and survival after each line of standard therapy. Many promising novel, chemotherapy-free therapies are in development, b
Externí odkaz:
https://doaj.org/article/569fb28841214450b4923be543937b12
Autor:
Thomas Roberts, Grace Uwenedi, Rachel Bruton, Graham McIlroy, Sarah Damery, Panagiota Sylla, Nicola Logan, Sam Scott, May Lau, Ahmed Elzaidi, Siobhan Plass, Soumyajit Mallick, Katie Spencer, Christine Stephens, Christopher Bentley, Guy Pratt, Jianmin Zuo, Shankara Paneesha, Brian Willett, Paul Moss, Helen Parry
Publikováno v:
Blood Cancer Journal, Vol 14, Iss 1, Pp 1-3 (2024)
Externí odkaz:
https://doaj.org/article/461ffaf1e5f841828038eef17f6ecdf9
Autor:
Jonathan Carmichael, Frances Seymour, Graham McIlroy, Sarrah Tayabali, Rosie Amerikanou, Sylvia Feyler, Rakesh Popat, Guy Pratt, Christopher Parrish, A. John Ashcroft, Graham H. Jackson, Gordon Cook
Publikováno v:
Blood Cancer Journal, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract The COVID-19 pandemic has had global healthcare impacts, including high mortality from SARS-CoV-2 infection in cancer patients; individuals with multiple myeloma (MM) are especially susceptible to poor outcomes. However, even for MM patients
Externí odkaz:
https://doaj.org/article/4261423c0dbc42d4ae909538097e3338
Autor:
Helen Parry, Graham McIlroy, Rachel Bruton, Sarah Damery, Grace Tyson, Nicola Logan, Chris Davis, Brian Willett, Jianmin Zuo, Myah Ali, Manjit Kaur, Christine Stephens, Dawn Brant, Ashley Otter, Tina McSkeane, Hayley Rolfe, Sian Faustini, Alex Richter, Sophie Lee, Farooq Wandroo, Salim Shafeek, Guy Pratt, Shankara Paneesha, Paul Moss
Publikováno v:
Journal of Hematology & Oncology, Vol 15, Iss 1, Pp 1-12 (2022)
Abstract Background Immune suppression is a clinical feature of chronic lymphocytic leukaemia (CLL), and patients show increased vulnerability to SARS-CoV-2 infection and suboptimal antibody responses. Method We studied antibody responses in 500 pati
Externí odkaz:
https://doaj.org/article/0b63fc659fe944b690bb8d6c08a4eb4d
Autor:
Rebecca Lloyd, Emmanouil Nikolousis, Bhuvan Kishore, Richard Lovell, Paneesha Shankara, Nervana Abou Zeid, Claire Horgan, Alkistis Kyra Panteliadou, Graham McIlroy, Evgenia Xenou, Maria Kaparou, Kathleen Holder, Vidhya Murthy, Alexandros Kanellopoulos
Publikováno v:
Cell Transplantation, Vol 29 (2020)
Stem cell transplantation remains the curative option for many patients with hematological malignancies. The long-term effects of these treatments on the patients and their immune systems have been extensively investigated, but there remains a paucit
Externí odkaz:
https://doaj.org/article/254b0a50aaac4c3581efe4175b3eee8a
Autor:
Suzana Ulian-Benitez, Simon Bishop, Istvan Foldi, Jill Wentzell, Chinenye Okenwa, Manuel G Forero, Bangfu Zhu, Marta Moreira, Mark Phizacklea, Graham McIlroy, Guiyi Li, Nicholas J Gay, Alicia Hidalgo
Publikováno v:
PLoS Genetics, Vol 13, Iss 8, p e1006968 (2017)
Neurotrophism, structural plasticity, learning and long-term memory in mammals critically depend on neurotrophins binding Trk receptors to activate tyrosine kinase (TyrK) signaling, but Drosophila lacks full-length Trks, raising the question of how t
Externí odkaz:
https://doaj.org/article/4511e4687c7c44eb8c7566d4706489f1
Autor:
Mhairi Copland, Daniel Slade, Graham McIlroy, Gillian Horne, Jenny L Byrne, Kate Rothwell, Kristian Brock, Hugues De Lavallade, Charles Craddock, Richard E Clark, Matthew L Smith, Rachel Fletcher, Rebecca Bishop, Dragana Milojkovic, Christina Yap
Publikováno v:
The Lancet Haematology. 9:e121-e132
Background: \ud Outcomes for patients with blast-phase chronic myeloid leukaemia are poor. Long-term survival depends on reaching a second chronic phase, followed by allogeneic haematopoietic stem-cell transplantation (HSCT). We investigated whether
Autor:
Jonathan Carmichael, Frances Seymour, Graham Mcilroy, Sarrah Tayabali, Rodothea Amerikanou, Sylvia Feyler, June Aung, Rakesh Popat, Guy Pratt, Christopher Parrish, John Ashcroft, Graham Jackson, Gordon Cook
The COVID-19 pandemic has had global healthcare impacts, including high mortality from SARS-CoV-2 infection in cancer patients; individuals with multiple myeloma (MM) are es-pecially susceptible to poor outcomes. However, even for MM patients who avo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f000509d0ab02e144eb3166ffa13d9d
https://doi.org/10.21203/rs.3.rs-2230271/v1
https://doi.org/10.21203/rs.3.rs-2230271/v1
Autor:
Kim Linton, Sridhar Chaganti, Kate Cwynarski, Josh Wright, Dominic Culligan, Roderick J. Johnson, Stefanie Thust, Ayesha S. Ali, Louise Hopkins, Aimee Jackson, Jeffery Smith, Andrew Davies, Andrés J.M. Ferreri, Shireen Kassam, Christopher P. Fox, Catherine Thomas, Ian Chau, David J. Lewis, Graham P. Collins, Nicolas Martinez-Calle, Dorothee P. Auer, Graham McIlroy
Publikováno v:
Fox, C P, Ali, A S, McIlroy, G, Thust, S, Martinez-Calle, N, Jackson, A E, Hopkins, L M, Thomas, C M, Kassam, S, Wright, J, Chaganti, S, Smith, J, Chau, I, Culligan, D, Linton, K M, Collins, G P, Ferreri, A J M, Lewis, D, Davies, A J, Johnson, R, Auer, D P & Cwynarski, K 2021, ' A phase 1/2 study of thiotepa-based immunochemotherapy in relapsed/refractory primary CNS lymphoma : the TIER trial ', Blood Advances, vol. 5, no. 20, pp. 4073-4082 . https://doi.org/10.1182/bloodadvances.2021004779
Relapsed or refractory primary central nervous system lymphoma (rrPCNSL) confers a poor prognosis with no accepted standard of care. Very few prospective studies have been conducted in this patient group. This study was a multicenter phase 1/2 study
Autor:
Ikhlaaq Ahmed, Andrea Hodgkinson, Rebecca Bishop, Ram Malladi, Jane Nunnick, Shamyla Siddique, Aimee Jackson, Fiona L Dignan, Mohamed Elhaneid, Graham McIlroy, Paul Moss, Charles Craddock, Rachel Protheroe
Publikováno v:
Bone Marrow Transplantation. 56:2948-2955
Chronic graft-versus-host disease (cGvHD) is a major cause of non-relapse morbidity and mortality following allogeneic stem cell transplant. Over half of patients with moderate or severe cGvHD fail to respond adequately to first-line treatment with s