Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Graham M. Widdowson"'
Autor:
Arlene W. Caggiula, Jeremiah Stamler, George Christakis, Marilyn Farrand, Graham M. Widdowson, Ruth Johnson, Stephen B. Hulley, Norman L. Lasser
Publikováno v:
Preventive Medicine. 10:443-475
The results are presented for the first 4 years of the Multiple Risk Factor Intervention Trial (MRFIT) nutrition intervention program. Study participants were at high risk (upper 10–15%) for Coronary Heart Disease (CHD). The Special Intervention (S
Publikováno v:
Clinical Chemistry. 20:1344-1348
A chemical test to distinguish smokers and nonsmokers is important in many epidemiologic studies. We have developed an automated method for determining serum thiocyanate by use of the reaction between thiocyanate and ferric ions to form a colored com
Publikováno v:
American Journal of Public Health. 67:545-549
Expired air carbon monoxide (CO) and serum thiocyanate (SCN) were used to asses exposure to cigarettes in 139 middle-aged men. Subjects who reported smoking cigarettes generally had CO levels exceeding 8ppm and SCN levels exceeding 100umol/L; non-smo
Publikováno v:
Clinical Chemistry. 24:313-320
Assessment of the significance of an observed set of serum chemical values for determining a person's state of health requires comparison with a set of defined reference values. We tested the assumption that a reference group of individuals, categori
Publikováno v:
Clinical Chemistry. 21:356-361
This report describes an interlaboratory comparison of enzymatic serum glucose methods as currently applied in several instrumental adaptations. Four spectrophotometric, hexokinase-based methods used with the Du Pont "aca," the Abbott "Bichromatic An
Autor:
A.C. Haff, Glenn E. Bartsch, Graham M. Widdowson, Stephen B. Hulley, Alain G. DuChene, Gerald R. Cooper
Publikováno v:
Controlled Clinical Trials. 7:158-165
Quality control was emphasized in the screening and clinic laboratory during the early stages of the trial to cover all aspects of screening, and in the later stages to cover local testing used to monitor the participant in the clinic and to guarante
Publikováno v:
Controlled Clinical Trials. 7:17-33
The acquisition of quality biochemical data in the MRFIT was enhanced by writing detailed protocols, instituting strict rules for collecting and shipping specimens, setting high goals for analytical performance, using reliable means to transfer data,
Autor:
Robert Schaffer, C C Garber, William T. Ryan, Graham M. Widdowson, G Kessler, N Carey, P H Duncan, W. D. Fellows, Nathan Gochman, Robert B. McComb, R Vanderlinde, W Miller, Robert W. Burnett, Richard J. Carter, David D. Bayse, B Tejeda, P Nast
Publikováno v:
Clinical Chemistry. 28:291-293
We describe the interlaboratory testing of a candidate Reference Method (Part I) for uric acid in serum. The method is based on the ultrasound spectrophotometric quantitation of uric acid before and after incubation with uricase. A comprehensive inve
Publikováno v:
JAMA. 238:2269
Determinants of circulating high density lipoproteins (HDL) were sought in 301 men studied during a year of participation in a coronary prevention program. Mean plasma HDL-cholesterol concentration rose by 2.8 mg/dl (6%) in the group receiving multif
Publikováno v:
J Res Natl Bur Stand A Phys Chem
There is a growing demand in clinical chemistry for analyses to be performed in a manner allowing comparisons of results among laboratories and, from time to time, in the same laboratory. Reliable comparability requires adequate procedures of standar