Patient-reported outcomes in schizophrenia patients treated with once-monthly extended-release risperidone in a long-term clinical study

Autor: Dhanda R, Varghese D, Nadipelli VR, Fava M, Joshi N, Solem CT, Graham JA, Learned SM, Heidbreder C

Publikováno v: Patient Preference and Adherence, Vol Volume 13, Pp 1037-1050 (2019)

Rahul Dhanda,1 Della Varghese,2 Vijay R Nadipelli,1 Maurizio Fava,3 Namita Joshi,2 Caitlyn T Solem,2 James A Graham,4 Susan M Learned,4 Christian Heidbreder51Global Health Economics and Outcomes Research, Indivior Inc, Richmond, VA 23235, USA; 2Real-

Externí odkaz: https://doaj.org/article/83ad417e1a1f4a9d860e0eb3fe9e2380

Progression-free survival as a surrogate endpoint in myeloma clinical trials: an evolving paradigm

Autor: Charlotte Pawlyn, Fredrik H. Schjesvold, David A. Cairns, L. J. Wei, Faith Davies, Omar Nadeem, Haifaa Abdulhaq, Maria-Victoria Mateos, Jacob Laubach, Katja Weisel, Heinz Ludwig, S. Vincent Rajkumar, Pieter Sonneveld, Graham Jackson, Gareth Morgan, Paul G. Richardson

Publikováno v: Blood Cancer Journal, Vol 14, Iss 1, Pp 1-8 (2024)

Abstract Measurement of overall survival (OS) remains the gold standard for interpreting the impact of new therapies for multiple myeloma in phase 3 trials. However, as outcomes have improved, it is increasingly challenging to use OS as the primary e

Externí odkaz: https://doaj.org/article/186d300a7c3d4b47adaec4bd25b20ac5

Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease

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C, Manning B, Woelcke J, Tan M, Manfreda S, Ponce T, Kam J, Saini R, Banker K, Salko T, Nandy P, Tawfik R, O’Neil G, Manne S, Jirvankar P, Lal S, Nema D, Jose J, Collins R, Bailey K, Blumenthal R, Colhoun H, Gersh B, Abreu M, Actis MV, Aiub J, Aiub F, Albisu J, Alvarisqueta A, Avalos V, Barreto M, Berli MA, Blumberg C, Bocanera M, Botta C, Bowen L, Budassi N, Buhlman S, Westberg JC, Carabajal T, Caruso G, Casala J, Cendali G, Coloma G, Berra FC, Cuneo C, Degennaro N, Dellasa M, Diaz M, Dos Santos P, Espinosa V, Facello A, Facello M, Farias E, Fernandez AA, Ferrari V, Pacora FF, Flores GS, Franco M, Gabito A, Viola HG, Garcia F, Garcia Duran R, Garcia Pinna J, Glenny J, Godoy Sanchez M, Grosse A, Guzman P, Hasbani E, Hominal M, Ibañez J, Jure H, Jure D, Vico ML, Liniado G, Luciardi H, Luquez H, Maehara G, Maffei L, Majul C, Mallagray M, Marinaro S, Martinez J, Massaccesi R, De Los Milagros Had M, Azize GM, Montana O, Montenegro E, Morell Y, Muntaner J, Navarrete S, Olmedo M, Paganini M, 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Publikováno v: Paediatrics Publications
New England journal of medicine, 377(12), 1119-1131. Massachussetts Medical Society

Background: Experimental and clinical data suggest that reducing inflammation without affecting lipid levels may reduce the risk of cardiovascular disease. Yet, the inflammatory hypothesis of atherothrombosis has remained unproved. Methods: We conduc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9352d7ff99dee51001e96d9b05970fb
https://doi.org/10.1056/nejmoa1707914

Final characterisation and design of the Gamma-ray Cherenkov Telescope (GCT) for the Cherenkov telescope array

Autor: Le Blanc, O, Fasola, G, Huet, JM, White, R, Dmytriiev, A, Sol, H, Zech, A, Abchiche, A, Amans, JP, Armstrong, TP, Barcelo, M, Berge, D, Brown, AM, Buchholtz, G, Chadwick, PM, Clark, P, Cotter, G, Dangeon, L, De Frondat, F, Deiml, P, Dournaux, JL, Duffy, C, Einecke, S, Flis, S, Funk, S, Giavitto, G, Gironnet, J, Graham, JA, Greenshaw, T, Hinton, JA, Jegouzo, I, Kraus, M, Lapington, JS, Laporte, P, Leach, SA, Lloyd, S, Minaya, IA, Morier, R, Okumura, A, Prokoph, H, Ross, D, Rowell, G, Rulten, CB, Schoorlemmer, H, Schmoll, J, Spencer, ST, Stephan, M, Stuik, R, Tajima, H, Thornhill, J, Tibaldo, L, Vink, J, Watson, JJ, Williams, J, Zink, A, Zorn, J, Project, CTAGCT

Publikováno v: SPIE 21 pp. (2018). doi:10.1117/12.2313158
Ground-based and Airborne Telescopes VII : [Proceedings]-SPIE, 2018.-ISBN 97815106195319781510619548-doi:10.1117/12.2313158
Ground-based and Airborne Telescopes VII : [Proceedings]-SPIE, 2018.-ISBN 97815106195319781510619548-doi:10.1117/12.2313158Ground-based and Airborne Telescopes VII, Austin, United States, 2018-06-10-2018-06-15
Ground-based and Airborne Telescopes VII: 10-15 June 2018, Austin, Texas, United States, 1
Proc.SPIE Int.Soc.Opt.Eng.
SPIE Astronomical Telescopes + Instrumentation 2018
SPIE Astronomical Telescopes + Instrumentation 2018, Jun 2018, Austin, United States. pp.1070010, ⟨10.1117/12.2313158⟩
GROUND-BASED AND AIRBORNE TELESCOPES VII

International audience; The Gamma-ray Cherenkov Telescope (GCT) is one of the telescopes proposed for the Small Sized Telescope (SST) section of CTA. Based on a dual-mirror Schwarzschild-Couder design, which allows for more compact telescopes and cam

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e122a6ca4887ced1294faaddb392d6f
https://bib-pubdb1.desy.de/record/418486

The prevalence and outcomes of frail older adults in clinical trials in multiple myeloma: A systematic review

Autor: Hira Mian, Arleigh McCurdy, Smith Giri, Shakira Grant, Bram Rochwerg, Erica Winks, Ashley E. Rosko, Monika Engelhardt, Charlotte Pawlyn, Gordon Cook, Graham Jackson, Sara Bringhen, Thierry Facon, Alessandra Larocca, Sonja Zweegman, Tanya M. Wildes

Publikováno v: Blood Cancer Journal, Vol 13, Iss 1, Pp 1-13 (2023)

Abstract Multiple myeloma (MM) is an incurable blood cancer that primarily affects older adults. Several frailty tools have been developed to address the heterogeneity of aging in this population. Uptake of these measures has been variable, leading t

Externí odkaz: https://doaj.org/article/076d33876b5743238d8aecfa4776d328