Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Graham J. Schapel"'
Autor:
Andrew B. Black, Reinhard Hiersemenzel, Graham J. Schapel, Roy G. Beran, Gytis Danta, Samuel F. Berkovic, Frank J.E. Vajda
Publikováno v:
Epilepsy Research. 63:1-9
Purpose: To evaluate the efficacy and tolerability of levetiracetam as add-on therapy in patients with refractory partial-onset seizures in a protocol designed to reflect clinical practice. Methods: All patients in this open-label, single-arm study e
Autor:
Samuel F. Berkovic, Graham J. Schapel, Andrew B. Black, John W. Dunne, Roy G. Beran, Roderick McKenzie, Daniel B. McLaughlin, Joseph Frasca, Ernest Somerville, Christine Kilpatrick, Gytis Danta, Keith Grainger
Publikováno v:
Epilepsia. 42:1335-1339
Summary: Purpose: To evaluate the safety, tolerability, efficacy, and impact on quality of life of gabapentin (Neurontin; GBP) as adjunctive therapy in patients with refractory partial seizures. Methods: AUS-STEPS was an open-label, multicenter, pros
Publikováno v:
Seizure. 6:479-483
A retrospective survey was carried out of add-on treatment with lamotrigine (LTG) and vigabatrin (GVG) in 109 children with severe epilepsy, treated between 1987 and 1994, identified from a total population of 300 patients seen annually, in a tertiar
Autor:
N Buchanan, Frank J.E. Vajda, Roy G. Beran, Graham J. Schapel, R. Mackenzie, G. Danta, G Sheean, Samuel F. Berkovic
Publikováno v:
Seizure. 5(4):259-265
The efficacy and tolerability of vigabatrin as add-on therapy was assessed in patients with uncontrolled partial seizures. Ninety-seven patients entered this seven-centre, double-blind, placebo-crossover study. Vigabatrin (2 g or 3 g) or placebo was
Publikováno v:
Epilepsia. 36:75-78
Urinary excretion of 6-sulfatoxymelatonin (aMT.6S), the hepatic metabolite of melatonin, was measured for three consecutive 8-h intervals, beginning at 0600 h, in 30 patients with untreated active epilepsy and in 19 healthy subjects. Excretion of aMT
Autor:
Roy G. Beran, M. L. Mashford, G. Davies, F. M. Dunagan, W. C. Yuen, Samuel F. Berkovic, Graham J. Schapel, Frank J.E. Vajda
Publikováno v:
Journal of Neurology, Neurosurgery & Psychiatry. 56:448-453
The results of a multicentre, randomised, double-blind, placebo controlled, crossover trial of lamotrigine as add-on therapy in patients with partial seizures poorly controlled by established antiepileptic drugs (AEDs) are presented. The study consis
Publikováno v:
The Lancet. 339:1111-1112
This is a letter to the editor describing a patient with acute transverse myelitis occurring after a tetanus toxoid booster administration. Although it is possible that the patient's myelopathy occurred independently of the vaccination, the timing an
Autor:
Michael A. Robinson, Terry E. Jones, Tim Read, Jeffrey M. Crocker, Gerald T. Davies, Philip E. Stanley, Graham J. Schapel, Trevor C. Draysey
Publikováno v:
Therapeutic Drug Monitoring. 3:137-142
Serum digoxin concentration (SDC) was compared with clinical and ancillary predictors as a guide to adjustment of digoxin dose and as a test for digitalis toxicity in a total of 76 hospitalized patients during a period of 9 months. The mean SDC (3.6
Autor:
Graham J. Schapel, Philip E. Stanley, Roy G. Beran, Richard H. C. Rischbieth, Mark Reid, Lloyd Sansom, Tim Read
Publikováno v:
Epilepsia. 21:379-386
This study records a comprehensive clinical protocol developed to assess seizure control and unwanted effects in 19 patients treated with sodium valproate (VPA). The assessment is based on six parameters individually ranked: seizure frequency, seizur
Publikováno v:
Australian and New Zealand Journal of Medicine. 19:55-57
A 55-year-old male with chronic lymphocytic leukemia developed a skin eruption after receiving oral cyclophosphamide. Subsequent rechallenge with parenteral cyclophosphamide led to recurrence of the skin lesions, which on biopsy were shown to be vasc