Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Graham J. G. Upton"'
Publikováno v:
Journal of Nucleic Acids, Vol 2010 (2010)
We have previously discovered that probes containing runs of four or more contiguous guanines are not reliable for measuring gene expression in the Human HG_U133A Affymetrix GeneChip data. These probes are not correlated with other members of their p
Externí odkaz:
https://doaj.org/article/1361276c83464806b1a9b35333b1319d
Publikováno v:
Global change biologyREFERENCES. 26(11)
Estimates of marine N2 fixation range from 52 to 73 Tg N/year, of which we calculate up to 84% is from Trichodesmium based on previous measurements of nifH gene abundance and our new model of Trichodesmium growth. Here, we assess the likely effects o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9fa4e0dfee395deb12082b54dbbb18b
https://pubmed.ncbi.nlm.nih.gov/32870567
https://pubmed.ncbi.nlm.nih.gov/32870567
Autor:
Ann M. Dixon, Antonia Lock, Leo Bowsher, Rachel Forfar, Graham Ladds, Cathryn Weston, Graham J. G. Upton, Christopher A. Reynolds
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1838(12):3036-3051
G protein-coupled receptors (GPCRs) are the largest family of cell-surface receptors in mammals and facilitate a range of physiological responses triggered by a variety of ligands. GPCRs were thought to function as monomers, however it is now accepte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ec53cbb824cd62fbcafa4c7ba92ca36
Publikováno v:
Environ. Sci.: Processes Impacts. 16:1646-1658
The work provides robust estimates of nutrient loads (nitrate and phosphate) from all UK catchments: as required by the Water Framework Directive to monitor catchments' health, and to inform management of these environments. To calculate nutrient loa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39d74fba02923010c2ba3cf1ab365562
https://doi.org/10.1039/c4em00021h
https://doi.org/10.1039/c4em00021h
Autor:
Graham J. G. Upton
Introduces the key concepts in the analysis of categoricaldata with illustrative examples and accompanying R code This book is aimed at all those who wish to discover how to analyze categorical data without getting immersed in complicated mathematics
Autor:
Graham J. G. Upton, Andrew Harrison
Publikováno v:
Nucleic Acids Research
An Affymetrix GeneChip consists of an array of hundreds of thousands of probes (each a sequence of 25 bases) with the probe values being used to infer the extent to which genes are expressed in the biological material under investigation. In this art
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ead047b9013a7d4e4809744b334b78be
http://europepmc.org/articles/PMC3479185
http://europepmc.org/articles/PMC3479185
Autor:
Henry S.X. Clark, Graham J. G. Upton, Nathan J. Kidley, Paul R. Gouldson, Lisa M. Simpson, Richard E. Smith, Bruck Taddese, Robert P. Bywater, George Psaroudakis, Christopher A. Reynolds, Frank E. Blaney, Ian D. Wall
Publikováno v:
Biochemical Society Transactions. 40:394-399
Our previously derived models of the active state of the β2-adrenergic receptor are compared with recently published X-ray crystallographic structures of activated GPCRs (G-protein-coupled receptors). These molecular dynamics-based models using expe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d916e93e5293aeb406959631b63444d
https://doi.org/10.1042/bst20110755
https://doi.org/10.1042/bst20110755
Publikováno v:
Advances in Water Resources. 32:1003-1010
The final stage in processing radar data so as to arrive at an estimated rain field typically involves a comparison of the preliminary radar-derived estimates of hourly rainfall with those observed by ground-based gauges. Often a mean field bias adju
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53d6961c555a8e862b038f9b9a8d0b73
https://doi.org/10.1016/j.advwatres.2008.08.010
https://doi.org/10.1016/j.advwatres.2008.08.010
Publikováno v:
Briefings in Bioinformatics. 10:259-277
The reliable interpretation of Affymetrix GeneChip data is a multi-faceted problem. The interplay between biophysics, bioinformatics and mining of GeneChip surveys is leading to new insights into how best to analyse the data. Many of the molecular pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2b5c320636d6481d4c0414e18ac3773
https://doi.org/10.1093/bib/bbp018
https://doi.org/10.1093/bib/bbp018
Autor:
Dan Brawn, Graham J. G. Upton
Publikováno v:
Atmospheric Research. 87:66-79
Atmospheric raindrop size distributions are believed to be often well approximated by gamma distributions. However, since disdrometers cannot measure the numbers of very small drops, the parameters of these distributions must be estimated from inform
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d7de108a2dcc1ee427b09407becf5d2
https://doi.org/10.1016/j.atmosres.2007.07.006
https://doi.org/10.1016/j.atmosres.2007.07.006