Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Graham H Diering"'
Autor:
Graham H Diering, Masayuki eNumata
Publikováno v:
Frontiers in Physiology, Vol 4 (2014)
Neuronal precursor cells extend multiple neurites during development, one of which extends to form an axon whereas others develop into dendrites. Chemical stimulation of N-methyl D-aspartate (NMDA) receptor in fully-differentiated neurons induces pro
Externí odkaz:
https://doaj.org/article/3397633235b74236979a7fe0a105449b
Autor:
Aruna D Balgi, Graham H Diering, Elizabeth Donohue, Karen K Y Lam, Bruno D Fonseca, Carla Zimmerman, Masayuki Numata, Michel Roberge
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e21549 (2011)
BACKGROUND: Acidification of the cytoplasm and the extracellular environment is associated with many physiological and pathological conditions, such as intense exercise, hypoxia and tumourigenesis. Acidification affects important cellular functions i
Externí odkaz:
https://doaj.org/article/c22fa0367eae4705bf9c3904c72596e0
Autor:
Carli K. Opland, Miles R. Bryan, Braxton Harris, Jake McGillion-Moore, Xu Tian, Youjun Chen, Michelle S. Itano, Graham H. Diering, Rick B. Meeker, Todd J. Cohen
Publikováno v:
iScience, Vol 26, Iss 6, Pp 106905- (2023)
Summary: Tau-mediated toxicity is associated with cognitive decline and Alzheimer’s disease (AD) progression. In particular, tau post-translational modifications (PTMs) are thought to generate aberrant tau species resulting in neuronal dysfunction.
Externí odkaz:
https://doaj.org/article/b7f1210596e04e69bf9b211b6c093c4c
Autor:
Shenée C. Martin, Kathryn K. Joyce, Kathryn M. Harper, Samuel J. Harp, Todd J. Cohen, Sheryl S. Moy, Graham H. Diering
Publikováno v:
Pharmaceuticals, Vol 17, Iss 3, p 319 (2024)
Sleep disruption is an expected component of aging and neurodegenerative conditions, including Alzheimer’s disease (AD). Sleep disruption has been demonstrated as a driver of AD pathology and cognitive decline. Therefore, treatments designed to mai
Externí odkaz:
https://doaj.org/article/7e26de891f7f48d69a3dc5e4560420ae
Autor:
Julia S. Lord, Sean M. Gay, Kathryn M. Harper, Viktoriya D. Nikolova, Kirsten M. Smith, Sheryl S. Moy, Graham H. Diering
Publikováno v:
Molecular Autism, Vol 13, Iss 1, Pp 1-19 (2022)
Abstract Background Patients with autism spectrum disorder (ASD) experience high rates of sleep disruption beginning early in life; however, the developmental consequences of this disruption are not understood. We examined sleep behavior and the cons
Externí odkaz:
https://doaj.org/article/c5e745d47c3941baa4b107535e8ce93b
Autor:
Graham H. Diering
Publikováno v:
Neurobiology of Stress, Vol 22, Iss , Pp 100512- (2023)
Sleep is a conserved and essential process that supports learning and memory. Synapses are a major target of sleep function and a locus of sleep need. Evidence in the literature suggests that the need for sleep has a cellular or microcircuit level ba
Externí odkaz:
https://doaj.org/article/08aed9389c45499c8547a68ab93952f4
Autor:
Michael Ye, Jessica C. McAfee, Stephanie L. Gupton, Jessica L. Bell, Graham H. Diering, Patrick Brennwald, Hyejung Won, Guendalina Rossi, Martilias S. Farrell, Melissa Plooster
Publikováno v:
J Neurosci
TSNARE1, which encodes the protein tSNARE1, is a high-confidence gene candidate for schizophrenia risk, but nothing is known about its cellular or physiological function. We identified the major gene products ofTSNARE1and their cytoplasmic localizati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::779e14456e56ceef99d6170876b1c54c
https://doi.org/10.1523/jneurosci.0556-21.2021
https://doi.org/10.1523/jneurosci.0556-21.2021
Autor:
Michael Ye, Sarah K. Monroe, Sean M. Gay, Michael L. Armstrong, Diane E. Youngstrom, Fabio L. Urbina, Stephanie L. Gupton, Nichole Reisdorph, Graham H. Diering
Publikováno v:
eneuro. 9:ENEURO.0276-22.2022
Neurons express overlapping homeostatic mechanisms to regulate synaptic function and network properties in response to perturbations of neuronal activity. Endocannabinoids (eCBs) are bioactive lipids synthesized in the post-synaptic compartments to r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45d03870db32d43a994c21ec606f50d7
https://doi.org/10.1523/eneuro.0276-22.2022
https://doi.org/10.1523/eneuro.0276-22.2022
Autor:
Sheneé C. Martin, Sean M. Gay, Michael L. Armstrong, Nila M. Pazhayam, Nichole Reisdorph, Graham H. Diering
Publikováno v:
Sleep
Sleep is an essential behavior that supports brain function and cognition throughout life, in part by acting on neuronal synapses. The synaptic signaling pathways that mediate the restorative benefits of sleep are not fully understood, particularly i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::620f2b883539573f7704bdd40b6d16d4
https://doi.org/10.1101/2021.05.10.443432
https://doi.org/10.1101/2021.05.10.443432
Autor:
Graham H. Diering, Richard L. Huganir
Publikováno v:
Neuron. 100:314-329
Changes in the properties and postsynaptic abundance of AMPA-type glutamate receptors (AMPARs) are major mechanisms underlying various forms of synaptic plasticity, including long-term potentiation (LTP), long-term depression (LTD), and homeostatic s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2bf6858ed27e335932c8ea15d2c51c3
https://doi.org/10.1016/j.neuron.2018.10.018
https://doi.org/10.1016/j.neuron.2018.10.018