Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Graham F. Pay"'
Autor:
Claudia Zuany-Amorim, Iben Dalum, Christoph Walker, Graham F. Pay, Søren Mouritsen, Anand Gautam, C. Manlius, Martin Roland Jensen
Publikováno v:
International archives of allergy and immunology. 133(2)
Background: Cytokines play an integral role in the coordination and persistence of allergic inflammatory processes and therefore represent prime targets for novel therapies in diseases such as asthma. Multiple attempts to generate low-molecular-weigh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82b8d53c872bf8519a6978a176ebf54c
https://pubmed.ncbi.nlm.nih.gov/14745228
https://pubmed.ncbi.nlm.nih.gov/14745228
Autor:
Laura Rosa Brunet, Graham A. W. Rook, Graham F. Pay, Alexandre Trifilieff, Claudia Zuany-Amorim, Christoph Walker, Gareth Bowen, C. Manlius
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 169(3)
This report examines the effect of heat-killed Mycobacterium vaccae in a mouse model of allergic pulmonary inflammation. The s.c. administration of M. vaccae 3 wk before the immunization significantly reduced Ag-induced airway hyperreactivity and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::057f096c0f9502fc89843f78bd111a93
https://pubmed.ncbi.nlm.nih.gov/12133976
https://pubmed.ncbi.nlm.nih.gov/12133976
Publikováno v:
Biochemical and biophysical research communications. 166(3)
The ability of heparin to interact with the Ins 1,4,5-P3 receptor is dependent on its chain length and degree of sulphation. Here we report results obtained with two sulphonated dye compounds of known structures and molecular weights below 1000, ciba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5108188573f0b30ba7685eefcea1148d
https://pubmed.ncbi.nlm.nih.gov/2154978
https://pubmed.ncbi.nlm.nih.gov/2154978
Publikováno v:
Pathophysiology of Haemostasis and Thrombosis. 10:165-175
The thioether metabolite of sulphinpyrazone is between 8 and 13 times more potent than the parent compound as a competitive inhibitor of human, guinea pig and rabbit platelet aggregation induced by sodium arachidonate. Of the other known metabolites,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31dbe2e487f539b91e444ab7b50936f0
https://doi.org/10.1159/000214400
https://doi.org/10.1159/000214400
Autor:
Martin D. Bootman, Michael A. Tones, David A. Lane, Bernard F. Higgins, Graham F. Pay, Ulf Lindahl
Publikováno v:
FEBS Letters. (1-2):105-108
Heparin is known to inhibit the binding of inositol 1,4,5-trisphosphate (Ins 1,4,5-P3) to high-affinity binding sites and to inhibit Ins 1,4,5-P3-induced Ca2+ release from intracellular membrane-bound stores [(1987) J. Biol. Chem. 262, 12132–12136;
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6889b0654777b186319690c19522cf37
Autor:
Graham F. Pay, Jean Ginsburg, R.B. Wallis, Denis Burley, Daniela Zelaschi, M. Dalton, E. Giorgades
Publikováno v:
Lancet (London, England). 1(8269)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0557c761032faecfb53cd29c82a7175b
https://pubmed.ncbi.nlm.nih.gov/6121137
https://pubmed.ncbi.nlm.nih.gov/6121137
Publikováno v:
Biochemical Society transactions. 8(6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05b29ad24742584b9da0fd8e5c33fd12
https://pubmed.ncbi.nlm.nih.gov/7461266
https://pubmed.ncbi.nlm.nih.gov/7461266
Publikováno v:
Thrombosis and Haemostasis.
In rabbits, high doses of sulphinpyrazone (S) result in prolonged inhibition of in vivo collagen-induced thrombocytopenia and platelet MDA production (Buchanan et al., Thromb. Res. 1978, 13., 883). After confirming these results we have shown in guin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc13cd8f30d63c0525ccbca6eee238db
https://doi.org/10.1055/s-0039-1684508
https://doi.org/10.1055/s-0039-1684508
Publikováno v:
Biochemical Society Transactions. 16:593-593
lnositol 1,4,5-trisphosphate [Ins( 1,4,5)P3] is produced by the phosphodiesteratic cleavage of the membrane lipid phosphatidylinositol4,S-bisphosphate in many cell types upon stimulation. It is thought to elevate intracellular free calcium ion concen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51d2bfb72b42a80561ec0194335c027b
https://doi.org/10.1042/bst0160593
https://doi.org/10.1042/bst0160593