Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Graham F. Maguire"'
Autor:
Philip W. Connelly, Bernard Zinman, Graham F. Maguire, Mary Mamakeesick, Stewart B. Harris, Robert A. Hegele, Ravi Retnakaran, Anthony J.G. Hanley
Publikováno v:
Journal of Lipid Research, Vol 50, Iss 6, Pp 1216-1222 (2009)
Paraoxonase 1 (PON1) has been reported to be associated with proteinuria in subjects with type 2 diabetes mellitus (T2DM). Plasma cystatin C is more accurate than creatinine for identifying stage 3 kidney disease in T2DM. We tested the hypothesis tha
Externí odkaz:
https://doaj.org/article/2dba582ae1764a17b9790b86df3efe58
Publikováno v:
Journal of Lipid Research, Vol 49, Iss 1, Pp 245-250 (2008)
Paraoxonase 1 (PON1) requires calcium for activity and is inactivated in the presence of EDTA. Because of this, studies to date have used serum or heparinized plasma for both activity and mass assays of PON1. Whole serum and EDTA plasma were analyzed
Externí odkaz:
https://doaj.org/article/7a29b890fcda4b05b5763c2ca8cefa19
Publikováno v:
Journal of Lipid Research, Vol 45, Iss 3, Pp 561-566 (2004)
Paraoxonase-1 (PON1) is known to be associated with high density lipoproteins. We optimized buffer conditions to obtain quantitative recovery of PON1 (arylesterase) activity and analyzed the distribution of PON1 in mice using a combination of size-ex
Externí odkaz:
https://doaj.org/article/a3255a69ae8e4b8b9107a6bb9cac6855
Autor:
Philip W. Connelly, Graham F. Maguire, Michelle M. Nash, Lindita Rapi, Andrew T. Yan, G. V. Ramesh Prasad
Publikováno v:
Journal of Lipids, Vol 2012 (2012)
South Asian renal transplant recipients have a higher incidence of cardiovascular disease compared with Caucasian renal transplant recipients. We carried out a study to determine whether paraoxonase 1, a novel biomarker for cardiovascular risk, was d
Externí odkaz:
https://doaj.org/article/8311f4ceb30c4664b595f3c5806de5c2
Autor:
Jing Zhang, Kevin Chien, Mark Naples, Dominic S. Ng, Dinushan Nesan, Graham F. Maguire, Amir Bashiri, Carolyn L. Cummins, Ian Sue-Chue-Lam, Khosrow Adeli, Ghazaleh Tavallaee, Lilia Magomedova
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1861:594-605
Non-alcoholic steatohepatitis (NASH), is the form of non-alcoholic fatty liver disease posing risk to progress into serious long term complications. Human and pre-clinical models implicate cellular cholesterol dysregulation playing important role in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3037dcf1a804707a18004c007fa5de35
https://doi.org/10.1016/j.bbalip.2016.04.005
https://doi.org/10.1016/j.bbalip.2016.04.005
Autor:
Lu Liu, Graham F. Maguire, Mark Naples, Lixin Li, Henry Pun, Dominic S. Ng, Christopher A. Baker, Lauren Hager, Khosrow Adeli, Lilia Magomedova, Jonathan Tam, Philip W. Connelly, Mohammad A. Hossain, Carolyn L. Cummins
Publikováno v:
Journal of Biological Chemistry. 287:20755-20768
We recently reported that lecithin:cholesterol acyltransferase (LCAT) knock-out mice, particularly in the LDL receptor knock-out background, are hypersensitive to insulin and resistant to high fat diet-induced insulin resistance (IR) and obesity. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9159fd9450d7ff3c66d7900779e21f0a
https://doi.org/10.1074/jbc.m112.340919
https://doi.org/10.1074/jbc.m112.340919
Autor:
Leon Vorobeichik, Michelle M. Nash, Graham F. Maguire, Michael Huang, Muhammad Mamdani, Lindita Rapi, Philip W. Connelly, Andrew T. Yan, G. V. Ramesh Prasad
Publikováno v:
Clinical Kidney Journal
Background. Ethnicity is an important determinant of post-renal transplant outcomes. Limited data are available on cardiovascular risk differences in kidney transplant recipients (KTR) based on ethnicity. Methods. A group of 129 clinically stable age
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a19cc77736583e0abaf665173dad207c
https://doi.org/10.1093/ckj/sfs033
https://doi.org/10.1093/ckj/sfs033
Autor:
Graham F. Maguire, Philip W. Connelly, Eric Lam, Chunhui Xie, Dominic S. Ng, Francisca Ugwu, Xianghong Zhu
Publikováno v:
Journal of Biological Chemistry. 279:7636-7642
Lecithin-cholesterol acyltransferase deficiency is frequently associated with hypertriglyceridemia (HTG) in animal models and humans. We investigated the mechanism of HTG in the ldlr-/- x lcat-/- (double knockout (dko)) mice using the ldlr-/- x lcat+
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c1066031fe02dec5159517efe9b0d8e
https://doi.org/10.1074/jbc.m309439200
https://doi.org/10.1074/jbc.m309439200
Publikováno v:
Cardiovascular Research. 58:712-720
Objective: High-density lipoprotein (HDL) is believed to protect against development of atherosclerosis by inhibiting the accumulation of oxidized lipids in low-density lipoprotein (LDL). Paradoxically, HDL lipid is more susceptible to oxidation than
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5c2dd2f14822174eb301dfad71dc62a
https://doi.org/10.1016/s0008-6363(03)00257-8
https://doi.org/10.1016/s0008-6363(03)00257-8
Autor:
Graham F. Maguire, Chiara Buono, Carolyn E. Come, Andrew H. Lichtman, Philip W. Connelly, George Stavrakis
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 23:454-460
Objective—The aim of this study was to investigate the influence of interferon-γ (IFN-γ) on atherosclerosis in low density lipoprotein receptor (LDLR)–null mice.Methods and Results—We cross-bred IFN-γ–deficient mice with LDLR-null mice and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80622c1355c8b2fc4f274de9901264f8
https://doi.org/10.1161/01.atv.0000059419.11002.6e
https://doi.org/10.1161/01.atv.0000059419.11002.6e