Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Graham F, Barber"'
Autor:
Juan D, Medina, Graham F, Barber, Maria M, Coronel, Michael D, Hunckler, Stephen W, Linderman, Michelle J, Quizon, Vahap, Ulker, Esma S, Yolcu, Haval, Shirwan, Andrés J, García
Publikováno v:
Journal of Biomedical Materials Research Part A. 110:1728-1737
Type 1 diabetes (T1D), an autoimmune disorder in which the insulin-producing β-cells in the islets of Langerhans in the pancreas are destroyed, afflicts over 1.6 million Americans. Although pancreatic islet transplantation has shown promise in treat
Autor:
Sabarinathan Ramachandran, Athanassios Sambanis, Collin J. Weber, Bernhard J. Hering, Bradley P. Weegman, Lucas A. Mutch, Melanie L. Graham, Amar Singh, Samuel A. Einstein, Michael Garwood, Graham F. Barber, Klearchos K. Papas, Jody J. Janecek, Susan A. Safley
Publikováno v:
Transplantation
Background We have utilized a noninvasive technique for measuring the partial pressure of oxygen (pO2) in alginate microcapsules implanted intraperitoneally in healthy nonhuman primates (NHPs). Average pO2 is important for determining if a transplant
Autor:
Graham F. Barber, Susan A. Safley, Robert W. Holdcraft, Stephanie Duncanson, Athanassios Sambanis, Lawrence S. Gazda, Collin J. Weber, Mark C. Poznansky
Publikováno v:
Xenotransplantation. 27
Background Our goal was to identify clinically relevant immunotherapies that synergize with microencapsulation to protect adult porcine islet (API) xenografts in diabetic NOD mice. We have shown previously that dual costimulatory blockade (CTLA4-Ig p
Autor:
Melissa A. Willman, Norma S. Kenyon, Susan A. Safley, Stephanie Duncanson, I. Raul Badell, Collin J. Weber, Dora M. Berman, Athanassios Sambanis, Robert W. Holdcraft, Lawrence S. Gazda, Camillo Ricordi, Neal N. Iwakoshi, Peter Thompson, Graham F. Barber
Publikováno v:
Xenotransplantation. 25(6)
Background Xenogeneic donors would provide an unlimited source of islets for the treatment of type 1 diabetes (T1D). The goal of this study was to assess the function of microencapsulated adult porcine islets (APIs) transplanted ip in streptozotocin
Autor:
Soumya Nalli, Dingwu Jia, Jyotirmay Sharma, Muhittin Onderci, Graham F. Barber, Collin J. Weber, Peter M. Thulé, Hong Yi, John Shires, Kereen Gordon, Susan A. Safley
Publikováno v:
World Journal of Surgery. 38:1251-1261
Insulin-secreting beta-like cells are vulnerable to diabetic autoimmunity. We hypothesized that human thyroid neuroendocrine (NE) cells could be engineered to secrete human insulin, be glucose-responsive, and avoid autoimmunity. Collagenase-digested
Autor:
Graham F. Barber, Athanassios Sambanis, Susan A. Safley, Kereen Gordan, Collin J. Weber, Sudhakar Muthyala
Publikováno v:
Xenotransplantation. 24(1)
Background Adult porcine islets (APIs) constitute a promising alternative to human islets in treating type 1 diabetes. The intrahepatic site has been used in preclinical primate studies of API xenografts; however, an estimated two-thirds of donor isl
Autor:
Susan A. Safley, Norma S. Kenyon, Dora M. Berman, Graham F. Barber, Melissa Willman, Stephanie Duncanson, Neal Iwakoshi, Robert Holdcraft, Lawrence Gazda, Peter Thompson, I. Raul Badell, Athanassios Sambanis, Camillo Ricordi, Collin J. Weber
Publikováno v:
Xenotransplantation. 25:e12480