Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Graham E. Jones"'
Autor:
Bryan K. Chan, Eileen Seward, Michael Lainchbury, Thomas F. Brewer, Le An, Toby Blench, Matthew W. Cartwright, Grace Ka Yan Chan, Edna F. Choo, Jason Drummond, Richard L. Elliott, Emanuela Gancia, Lewis Gazzard, Baihua Hu, Graham E. Jones, Xifeng Luo, Andrew Madin, Sushant Malhotra, John G. Moffat, Jodie Pang, Laurent Salphati, Christopher J. Sneeringer, Craig E. Stivala, Binqing Wei, Weiru Wang, Ping Wu, Timothy P. Heffron
Publikováno v:
ACS Med Chem Lett
[Image: see text] Hematopoietic progenitor kinase 1 (HPK1) is implicated as a negative regulator of T-cell receptor-induced T-cell activation. Studies using HPK1 kinase-dead knock-in animals have demonstrated the loss of HPK1 kinase activity resulted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f11f71008647153e48985266e826374
https://doi.org/10.1021/acsmedchemlett.1c00473
https://doi.org/10.1021/acsmedchemlett.1c00473
Autor:
Graham E. Jones, Andrew B. Holmes
Publikováno v:
Tetrahedron Letters. 23:3203-3206
Acylation of 4-substituted 1-trimethylsilylbuta-1,3-diynes (2) with suitable acyl halides in the presence of titanium tetrachloride gave diacetylenic ketones (3) including the naturally occurring compounds (3c), (3e), and (3f).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67a870930a8e559782538cdd774e3cf9
https://doi.org/10.1016/s0040-4039(00)88596-2
https://doi.org/10.1016/s0040-4039(00)88596-2
Autor:
Andrew B. Holmes, Graham E. Jones
Publikováno v:
Tetrahedron Letters. 21:3111-3112
Lithium trimethylsilylbutadiyne (2) is alkylated by primary alkyl halides in THF-HMPA or via the ethylenediamine complex (4) in THF-DMSO to give the title compounds (3) in good yield.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48e7577697017806d64fc9be54054fd3
https://doi.org/10.1016/s0040-4039(00)77422-3
https://doi.org/10.1016/s0040-4039(00)77422-3