Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Graham D. Hamblin"'
Autor:
John D. Bagert, Alborz Mahdavi, Erin M. Schuman, Graham D. Hamblin, Cathy Dong, Michael J. Sweredoski, Sonja Hess, Granton A. Jindal, David A. Tirrell
Publikováno v:
Journal of the American Chemical Society
Methods for cell-selective analysis of proteome dynamics will facilitate studies of biological processes in multicellular organisms. Here we describe a mutant murine methionyl-tRNA synthetase (designated L274GMmMetRS) that charges the noncanonical am
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f899bd314f2164e3bd3b9bafbecb7f65
https://doi.org/10.1021/jacs.5b08980
https://doi.org/10.1021/jacs.5b08980
Publikováno v:
Nature Chemistry. 7:295-300
DNA nanotubes offer a high aspect ratio and rigidity, attractive attributes for the controlled assembly of hierarchically complex linear arrays. It is highly desirable to control the positioning of rungs along the backbone of the nanotubes, minimize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f67f79c61e8c6442a552e41bed6ca45a
https://doi.org/10.1038/nchem.2184
https://doi.org/10.1038/nchem.2184
Autor:
Robert Godin, Graham D. Hamblin, Amani A. Hariri, Hanadi F. Sleiman, Gonzalo Cosa, Paul W. Wiseman, Jean-Francois Desjardins, Jack S. Hardwick
Publikováno v:
Bioconjugate chemistry. 28(9)
A wide variety of approaches have become available for the fabrication of nanomaterials with increasing degrees of complexity, precision, and speed while minimizing cost. Their quantitative characterization, however, remains a challenge. Analytical m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1680ea2000f29437a6d54de36c4a0fbc
https://pubmed.ncbi.nlm.nih.gov/28777539
https://pubmed.ncbi.nlm.nih.gov/28777539
Autor:
Karina M. M. Carneiro, Lawrence Panasci, Hanadi F. Sleiman, Joel Neves Briard, Lilian Amrein, Antoine G. Godin, Paul W. Wiseman, Thomas G. W. Edwardson, Graham D. Hamblin, Johans Fakhoury, Katherine E. Bujold
Publikováno v:
Chem. Sci.. 5:2449-2455
Here, we demonstrate a new approach for the design and assembly of a dynamic DNA cube with an addressable cellular uptake profile. This cube can be selectively unzipped from a 3D to a flat two-dimensional structure in the presence of a specific nucle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cda991a911c66029abce67df7dfb7c8d
https://doi.org/10.1039/c4sc00646a
https://doi.org/10.1039/c4sc00646a
Autor:
Karina M. M. Carneiro, Amani A. Hariri, Kai L. Lau, Graham D. Hamblin, Gonzalo Cosa, Hanadi F. Sleiman
Publikováno v:
ACS Nano. 7:3022-3028
DNA nanotubes have great potential as nanoscale scaffolds for the organization of materials and the templation of nanowires and as drug delivery vehicles. Current methods for making DNA nanotubes either rely on a tile-based step-growth polymerization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcee68224c893e41e65392b700fe5eaf
https://doi.org/10.1021/nn4006329
https://doi.org/10.1021/nn4006329
Publikováno v:
Current opinion in chemical biology. 36
Cells alter the proteome to respond to environmental and developmental cues. Global analysis of proteomic responses is of limited value in heterogeneous environments, where there is no ‘average’ cell. Advances in sequencing, protein labeling, mas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72d562c03b29501a20b599157995637a
https://pubmed.ncbi.nlm.nih.gov/28088696
https://pubmed.ncbi.nlm.nih.gov/28088696
Autor:
Karina M. M. Carneiro, Hanadi F. Sleiman, Graham D. Hamblin, Katherine E. Bujold, Johans Fakhoury
Publikováno v:
Journal of the American Chemical Society. 134:2888-2891
DNA nanotubes hold promise as scaffolds for protein organization, as templates of nanowires and photonic systems, and as drug delivery vehicles. We present a new DNA-economic strategy for the construction of DNA nanotubes with a backbone produced by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::886bd312b63114cb3d416ec61dbc6067
https://doi.org/10.1021/ja2107492
https://doi.org/10.1021/ja2107492
Autor:
Hassan S. Bazzi, Kevin D. Hänni, Graham D. Hamblin, Hanadi F. Sleiman, Justin W. Conway, Christopher K. McLaughlin, Manoj K. Nayak, Karina M. M. Carneiro
Publikováno v:
Journal of the American Chemical Society
Here, we introduce a 3D-DNA construction method that assembles a minimum number of DNA strands in quantitative yield, to give a scaffold with a large number of single-stranded arms. This DNA frame is used as a core structure to organize other functio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bec578b8a95e588ffac06406c8f0c019
Autor:
Georgios Rizis, Karina M. M. Carneiro, Christopher K. McLaughlin, Hassan S. Bazzi, Graham D. Hamblin, Kevin D. Hänni, Hanadi F. Sleiman, Manoj K. Nayak, Johans Fakhoury
Publikováno v:
Chemical Science
DNA nanotubes are an attractive class of materials that can be assembled with precise control over their size, shape, length and porosity, and can encapsulate and release materials in response to specific added molecules. In parallel, block copolymer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cb115e11b38b3649a48e63ea0cf953d
Autor:
Pierre Karam, Graham D. Hamblin, Hanadi F. Sleiman, Pik Kwan Lo, Christopher K. McLaughlin, Gonzalo Cosa, Faisal A. Aldaye
Publikováno v:
Nature Chemistry. 2:319-328
Nanotubes hold promise for a number of biological and materials applications because of their high aspect ratio and encapsulation potential. A particularly attractive goal is to access nanotubes that exert well-defined control over their cargo, such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1d0d90060fdb394f781ea1d695a064f
https://doi.org/10.1038/nchem.575
https://doi.org/10.1038/nchem.575