Zobrazeno 1 - 10
of 351
pro vyhledávání: '"Graham C. Walker"'
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Ribosome assembly is a complex fundamental cellular process that involves assembling multiple ribosomal proteins and several ribosomal RNA species in a highly coordinated yet flexible and resilient manner. The highly conserved YbeY protein is a singl
Externí odkaz:
https://doaj.org/article/71afddf779734080ac39f7d83c67760e
Publikováno v:
mBio, Vol 13, Iss 1 (2022)
ABSTRACT Various lethal stresses, including bactericidal antibiotics, can trigger the production of reactive oxygen species (ROS) that contribute to killing. Incomplete base excision repair (BER) of oxidized nucleotides, especially 8-oxo-dG, has been
Externí odkaz:
https://doaj.org/article/65162e530d514d4b836c0ea4a07f8c09
Autor:
Peter Belenky, Jonathan D. Ye, Caroline B.M. Porter, Nadia R. Cohen, Michael A. Lobritz, Thomas Ferrante, Saloni Jain, Benjamin J. Korry, Eric G. Schwarz, Graham C. Walker, James J. Collins
Publikováno v:
Cell Reports, Vol 13, Iss 5, Pp 968-980 (2015)
Understanding how antibiotics impact bacterial metabolism may provide insight into their mechanisms of action and could lead to enhanced therapeutic methodologies. Here, we profiled the metabolome of Escherichia coli after treatment with three differ
Externí odkaz:
https://doaj.org/article/99544848d82848799c462c9cf6788572
Autor:
Markus F. F. Arnold, Mohammed Shabab, Jon Penterman, Kevin L. Boehme, Joel S. Griffitts, Graham C. Walker
Publikováno v:
mBio, Vol 8, Iss 4 (2017)
ABSTRACT The model legume species Medicago truncatula expresses more than 700 nodule-specific cysteine-rich (NCR) signaling peptides that mediate the differentiation of Sinorhizobium meliloti bacteria into nitrogen-fixing bacteroids. NCR peptides are
Externí odkaz:
https://doaj.org/article/105af1bd7c534cd1b511226dc0dd1898
Autor:
Maarten Vercruysse, Caroline Köhrer, Yang Shen, Sandra Proulx, Anubrata Ghosal, Bryan W. Davies, Uttam L. RajBhandary, Graham C. Walker
Publikováno v:
mBio, Vol 7, Iss 6 (2016)
ABSTRACT YbeY is part of a core set of RNases in Escherichia coli and other bacteria. This highly conserved endoribonuclease has been implicated in several important processes such as 16S rRNA 3′ end maturation, 70S ribosome quality control, and re
Externí odkaz:
https://doaj.org/article/17b5a820c273493788ed9a01f2254ec3
Autor:
Michiko E. Taga, Graham C. Walker
Publikováno v:
Molecular Plant-Microbe Interactions, Vol 23, Iss 12, Pp 1643-1654 (2010)
Vitamin B12 (cobalamin) is a critical cofactor for animals and protists, yet its biosynthesis is limited to prokaryotes. We previously showed that the symbiotic nitrogen-fixing alphaproteobacterium Sinorhizobium meliloti requires cobalamin to establi
Externí odkaz:
https://doaj.org/article/0212a6776ff84032a4364f807cc1063a
An essential resource for all scientists researching cellular responses to DNA damage.
Autor:
Siva Sankari, Vignesh M. P. Babu, Ke Bian, Areej Alhhazmi, Mary C. Andorfer, Dante M. Avalos, Tyler A. Smith, Kwan Yoon, Catherine L. Drennan, Michael B. Yaffe, Sebastian Lourido, Graham C. Walker
Publikováno v:
Nat Microbiol
Symbiotic partnerships with rhizobial bacteria enable legumes to grow without nitrogen fertilizer because rhizobia convert atmospheric nitrogen gas into ammonia via nitrogenase. After Sinorhizobium meliloti penetrate the root nodules that they have e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec24cf253fadd73306d48ad0d5109cee
https://doi.org/10.1038/s41564-022-01192-y
https://doi.org/10.1038/s41564-022-01192-y
Autor:
Kerry Silva McPherson, Alessandro A. Rizzo, Heidi Erlandsen, Nimrat Chatterjee, Graham C. Walker, Dmitry M. Korzhnev
Publikováno v:
The Journal of biological chemistry.
Translesion synthesis (TLS) DNA polymerase Polζ is crucial for the bypass replication over sites of DNA damage. The Rev7 subunit of Polζ is a HORMA protein that facilitates recruitment of Polζ to the replication fork via interactions with the cata
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdc6a4d32cb7e659aeb6e2c45226f919
https://pubmed.ncbi.nlm.nih.gov/36592930
https://pubmed.ncbi.nlm.nih.gov/36592930
Autor:
Pei Zhou, Nimrat Chatterjee, Sophia M Min, Oliver Jonas, Graham C. Walker, Michael T. Hemann, Matthew G. Vander Heiden, Evan C. Lien, Matthew Whitman, Cynthia A. Harris, Alba Luengo, Jiyong Hong
Publikováno v:
Proc Natl Acad Sci U S A
REV1/POLζ-dependent mutagenic translesion synthesis (TLS) promotes cell survival after DNA damage but is responsible for most of the resulting mutations. A novel inhibitor of this pathway, JH-RE-06, promotes cisplatin efficacy in cancer cells and mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c7c722beb814c376f76b1eb101b6bda
https://doi.org/10.1073/pnas.2016064117
https://doi.org/10.1073/pnas.2016064117