Zobrazeno 1 - 10
of 295
pro vyhledávání: '"Graham Ball"'
Autor:
Behnaz Saidy, Richa Vasan, Rosie Durant, Megan-Rose Greener, Adelynn Immanuel, Andrew R. Green, Emad Rakha, Ian Ellis, Graham Ball, Stewart G. Martin, Sarah J. Storr
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract DARPP-32 is a key regulator of protein-phosphatase-1 (PP-1) and protein kinase A (PKA), with its function dependent upon its phosphorylation state. We previously identified DKK1 and GRB7 as genes with linked expression using Artificial Neura
Externí odkaz:
https://doaj.org/article/8c1ee39167a0487ca4d3a7902d3e505d
Autor:
Farah Omran, Alice M. Murphy, Awais Z. Younis, Ioannis Kyrou, Jana Vrbikova, Vojtech Hainer, Petra Sramkova, Martin Fried, Graham Ball, Gyanendra Tripathi, Sudhesh Kumar, Philip G. McTernan, Mark Christian
Publikováno v:
BMC Medicine, Vol 21, Iss 1, Pp 1-17 (2023)
Abstract Background Dysfunctional adipose tissue (AT) is known to contribute to the pathophysiology of metabolic disease, including type 2 diabetes mellitus (T2DM). This dysfunction may occur, in part, as a consequence of gut-derived endotoxaemia ind
Externí odkaz:
https://doaj.org/article/866329b7286347818635c4f34ca555da
Autor:
Alanoud Aladel, Alice M. Murphy, Jenny Abraham, Neha Shah, Thomas M. Barber, Graham Ball, Vinod Menon, Milan K. Piya, Philip G. McTernan
Publikováno v:
Nutrients, Vol 14, Iss 10, p 2052 (2022)
Weight Loss Surgery (WLS), including sleeve-gastrectomy (SG), results in significant weight loss and improved metabolic health in severe obesity (BMI ≥ 35 kg/m2). Previous studies suggest post-operative health benefits are impacted by nutrient defi
Externí odkaz:
https://doaj.org/article/3925abf8a7194d49bfd5dcfd154f2d70
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Sepsis is defined as dysregulated host response caused by systemic infection, leading to organ failure. It is a life-threatening condition, often requiring admission to an intensive care unit (ICU). The causative agents and processes involved are mul
Externí odkaz:
https://doaj.org/article/d4c2520d95b94883b93176240f48bfdf
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0205818 (2018)
The aim was to objectively identify key performance indicators in professional soccer that influence outfield players' league status using an artificial neural network. Mean technical performance data were collected from 966 outfield players' (mean S
Externí odkaz:
https://doaj.org/article/d5c243a051444039870532ff3d8d3e9c
Autor:
Tarek M. A. Abdel-Fatah, Reem Ali, Maaz Sadiq, Paul M. Moseley, Katia A. Mesquita, Graham Ball, Andrew R. Green, Emad A. Rakha, Stephen Y. T. Chan, Srinivasan Madhusudan
Publikováno v:
Cancers, Vol 11, Iss 8, p 1149 (2019)
Genomic instability could be a beneficial predictor for anthracycline or taxane chemotherapy. We interrogated 188 DNA repair genes in the METABRIC cohort (n = 1980) to identify genes that influence overall survival (OS). We then evaluated the clinico
Externí odkaz:
https://doaj.org/article/9c0efb9db5044a22a2071ee65ef891a4
Autor:
Sajid Javed, Leanne Marsay, Alice Wareham, Kuiama S Lewandowski, Ann Williams, Michael J Dennis, Sally Sharpe, Richard Vipond, Nigel Silman, Graham Ball, Karen E Kempsell
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159783 (2016)
[This corrects the article DOI: 10.1371/journal.pone.0154320.].
Externí odkaz:
https://doaj.org/article/b8dad59035b04b598174dfe91b9fb593
Autor:
Sajid Javed, Leanne Marsay, Alice Wareham, Kuiama S Lewandowski, Ann Williams, Michael J Dennis, Sally Sharpe, Richard Vipond, Nigel Silman, Graham Ball, Karen E Kempsell
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0154320 (2016)
A temporal study of gene expression in peripheral blood leukocytes (PBLs) from a Mycobacterium tuberculosis primary, pulmonary challenge model Macaca fascicularis has been conducted. PBL samples were taken prior to challenge and at one, two, four and
Externí odkaz:
https://doaj.org/article/ac8b5b308364458d806563b68366957d
Publikováno v:
Genes, Vol 9, Iss 3, p 151 (2018)
Nitrogen (N) fertilizer has a major influence on the yield and quality. Understanding and optimising the response of crop plants to nitrogen fertilizer usage is of central importance in enhancing food security and agricultural sustainability. In this
Externí odkaz:
https://doaj.org/article/eec173d2bf1247339d9ba652b770838f
Autor:
Ailbhe M McDermott, Nicola Miller, Deirdre Wall, Lorcan M Martyn, Graham Ball, Karl J Sweeney, Michael J Kerin
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e87032 (2014)
INTRODUCTION: Breast cancer is a common disease with distinct tumor subtypes phenotypically characterized by ER and HER2/neu receptor status. MiRNAs play regulatory roles in tumor initiation and progression, and altered miRNA expression has been demo
Externí odkaz:
https://doaj.org/article/363af2d371b44cc995c3619a0459e999