Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Graham B Wiley"'
Autor:
Astrid Rasmussen, Kathy L Sivils, Joel M Guthridge, Judith A James, Jennifer A Kelly, Patrick M Gaffney, Jonathan D Wren, Stuart B Glenn, R Hal Scofield, Christopher J Lessard, Donald U Stone, David M Lewis, Lida Radfar, A Darise Farris, John A Ice, Courtney G Montgomery, Michelle L Joachims, Bhuwan Khatri, Chuang Li, Kandice L Tessneer, Anna M Stolarczyk, Nicolas Means, Kiely M Grundahl, Graham B Wiley, Indra Adrianto
Publikováno v:
RMD Open, Vol 8, Iss 2 (2022)
Objective Sjögren’s disease (SjD) is an autoimmune disease characterised by inflammatory destruction of exocrine glands. Patients with autoantibodies to Ro/SSA (SjDRo+) exhibit more severe disease. Long non-coding RNAs (lncRNAs) are a functionally
Externí odkaz:
https://doaj.org/article/47cfe83cffdf4adfa6b8c72936c25cd6
Autor:
Prithvi Raj, Ekta Rai, Ran Song, Shaheen Khan, Benjamin E Wakeland, Kasthuribai Viswanathan, Carlos Arana, Chaoying Liang, Bo Zhang, Igor Dozmorov, Ferdicia Carr-Johnson, Mitja Mitrovic, Graham B Wiley, Jennifer A Kelly, Bernard R Lauwerys, Nancy J Olsen, Chris Cotsapas, Christine K Garcia, Carol A Wise, John B Harley, Swapan K Nath, Judith A James, Chaim O Jacob, Betty P Tsao, Chandrashekhar Pasare, David R Karp, Quan Zhen Li, Patrick M Gaffney, Edward K Wakeland
Publikováno v:
eLife, Vol 5 (2016)
Targeted sequencing of sixteen SLE risk loci among 1349 Caucasian cases and controls produced a comprehensive dataset of the variations causing susceptibility to systemic lupus erythematosus (SLE). Two independent disease association signals in the H
Externí odkaz:
https://doaj.org/article/9cb126754a5c4c41a78ee8db59f27c5a
Autor:
Kevin M Brown, Elena Suvorova, Andrew Farrell, Aaron McLain, Ashley Dittmar, Graham B Wiley, Gabor Marth, Patrick M Gaffney, Marc Jan Gubbels, Michael White, Ira J Blader
Publikováno v:
PLoS Pathogens, Vol 10, Iss 6, p e1004180 (2014)
The simultaneous targeting of host and pathogen processes represents an untapped approach for the treatment of intracellular infections. Hypoxia-inducible factor-1 (HIF-1) is a host cell transcription factor that is activated by and required for the
Externí odkaz:
https://doaj.org/article/9c745ecfde8041e694bf6c423b375519
Autor:
Ramesh Buyyarapu, Ramesh V Kantety, John Z Yu, Zhanyou Xu, Russell J Kohel, Richard G Percy, Simone Macmil, Graham B Wiley, Bruce A Roe, Govind C Sharma
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76757 (2013)
Although new and emerging next-generation sequencing (NGS) technologies have reduced sequencing costs significantly, much work remains to implement them for de novo sequencing of complex and highly repetitive genomes such as the tetraploid genome of
Externí odkaz:
https://doaj.org/article/e08fbdbb8d0647bfb5a792dca545942f
Publikováno v:
PLoS Genetics, Vol 9, Iss 9, p e1003750 (2013)
Functional characterization of causal variants present on risk haplotypes identified through genome-wide association studies (GWAS) is a primary objective of human genetics. In this report, we evaluate the function of a pair of tandem polymorphic din
Externí odkaz:
https://doaj.org/article/d9b6170e2e3447658ed1e2fe9ae21b04
Autor:
Jeong-Hyeon Choi, Yajun Li, Juyuan Guo, Lirong Pei, Tibor A Rauch, Robin S Kramer, Simone L Macmil, Graham B Wiley, Lynda B Bennett, Jennifer L Schnabel, Kristen H Taylor, Sun Kim, Dong Xu, Arun Sreekumar, Gerd P Pfeifer, Bruce A Roe, Charles W Caldwell, Kapil N Bhalla, Huidong Shi
Publikováno v:
PLoS ONE, Vol 5, Iss 9 (2010)
Follicular lymphoma (FL) is a form of non-Hodgkin's lymphoma (NHL) that arises from germinal center (GC) B-cells. Despite the significant advances in immunotherapy, FL is still not curable. Beyond transcriptional profiling and genomics datasets, ther
Externí odkaz:
https://doaj.org/article/35e21c937e8148c5ae124b8913c2cbd8
Autor:
Yao Fu, Graham B. Wiley, Richard Pelikan, Jennifer A. Kelly, Patrick M. Gaffney, Kandice L. Tessneer, Satish Pasula, Jaanam Gopalakrishnan
Publikováno v:
Arthritis & Rheumatology. 74:163-173
Objective Genetic variants spanning the ubiquitin-conjugating enzyme E2 L3 (UBE2L3) gene are associated with increased expression of the UBE2L3-encoded E2 ubiquitin-conjugating enzyme, UbcH7, that facilitates activation of proinflammatory NF-κB sign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bcdfaa1f75c23d75c19f45f5aabff8b2
https://doi.org/10.1002/art.41925
https://doi.org/10.1002/art.41925
Autor:
Michelle L Joachims, Bhuwan Khatri, Chuang Li, Kandice L Tessneer, John A Ice, Anna M Stolarczyk, Nicolas Means, Kiely M Grundahl, Stuart B Glenn, Jennifer A Kelly, David M Lewis, Lida Radfar, Donald U Stone, Joel M Guthridge, Judith A James, R Hal Scofield, Graham B Wiley, Jonathan D Wren, Patrick M Gaffney, Courtney G Montgomery, Kathy L Sivils, Astrid Rasmussen, A Darise Farris, Indra Adrianto, Christopher J Lessard
Publikováno v:
RMD open. 8(2)
ObjectiveSjögren’s disease (SjD) is an autoimmune disease characterised by inflammatory destruction of exocrine glands. Patients with autoantibodies to Ro/SSA (SjDRo+) exhibit more severe disease. Long non-coding RNAs (lncRNAs) are a functionally
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e3450542a5119125523232996309e11
https://pubmed.ncbi.nlm.nih.gov/36456101
https://pubmed.ncbi.nlm.nih.gov/36456101
Autor:
Yogesh K. Chutake, Christina Lam, Matthew Gilliam, Layne N. Rodden, Lauren A. Hauser, David A. Lynch, Sanjay I. Bidichandani, Kaitlyn M. Gilliam, Joel M. Gottesfeld, Graham B. Wiley, Elisabetta Soragni, Michael P. Anderson
Publikováno v:
Human Molecular Genetics
Friedreich ataxia (FRDA) is typically caused by homozygosity for an expanded GAA triplet-repeat in intron 1 of the FXN gene, which results in transcriptional deficiency via epigenetic silencing. Most patients are homozygous for alleles containing > 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d48becc41650ce92ac04e7430ae01ef6
https://doi.org/10.1093/hmg/ddaa267
https://doi.org/10.1093/hmg/ddaa267
Autor:
Matthew J. Miller, Graham B. Wiley
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 6, Pp 1829-1836 (2020)
Woodpeckers are found in nearly every part of the world and have been important for studies of biogeography, phylogeography, and macroecology. Woodpecker hybrid zones are often studied to understand the dynamics of introgression between bird species.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1314703589695f58f1555865c125eb47
https://doi.org/10.1534/g3.120.401059
https://doi.org/10.1534/g3.120.401059