Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Graham B Wiley"'
Autor:
Astrid Rasmussen, Kathy L Sivils, Joel M Guthridge, Judith A James, Jennifer A Kelly, Patrick M Gaffney, Jonathan D Wren, Stuart B Glenn, R Hal Scofield, Christopher J Lessard, Donald U Stone, David M Lewis, Lida Radfar, A Darise Farris, John A Ice, Courtney G Montgomery, Michelle L Joachims, Bhuwan Khatri, Chuang Li, Kandice L Tessneer, Anna M Stolarczyk, Nicolas Means, Kiely M Grundahl, Graham B Wiley, Indra Adrianto
Publikováno v:
RMD Open, Vol 8, Iss 2 (2022)
Objective Sjögren’s disease (SjD) is an autoimmune disease characterised by inflammatory destruction of exocrine glands. Patients with autoantibodies to Ro/SSA (SjDRo+) exhibit more severe disease. Long non-coding RNAs (lncRNAs) are a functionally
Externí odkaz:
https://doaj.org/article/47cfe83cffdf4adfa6b8c72936c25cd6
Autor:
Richard C. Pelikan, Jennifer A. Kelly, Yao Fu, Caleb A. Lareau, Kandice L. Tessneer, Graham B. Wiley, Mandi M. Wiley, Stuart B. Glenn, John B. Harley, Joel M. Guthridge, Judith A. James, Martin J. Aryee, Courtney Montgomery, Patrick M. Gaffney
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Disease risk variants can exert their influence on phenotypes by altering epigenome function. Here, Pelikan et al. show that variants inducing allelic imbalance in histone marks in lymphoblastoid cell lines from lupus patients are enriched in autoimm
Externí odkaz:
https://doaj.org/article/0996b48baa6642459f605c36bd0e9936
Autor:
Yao Fu, Graham B. Wiley, Richard Pelikan, Jennifer A. Kelly, Patrick M. Gaffney, Kandice L. Tessneer, Satish Pasula, Jaanam Gopalakrishnan
Publikováno v:
Arthritis & Rheumatology. 74:163-173
Objective Genetic variants spanning the ubiquitin-conjugating enzyme E2 L3 (UBE2L3) gene are associated with increased expression of the UBE2L3-encoded E2 ubiquitin-conjugating enzyme, UbcH7, that facilitates activation of proinflammatory NF-κB sign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bcdfaa1f75c23d75c19f45f5aabff8b2
https://doi.org/10.1002/art.41925
https://doi.org/10.1002/art.41925
Autor:
Michelle L Joachims, Bhuwan Khatri, Chuang Li, Kandice L Tessneer, John A Ice, Anna M Stolarczyk, Nicolas Means, Kiely M Grundahl, Stuart B Glenn, Jennifer A Kelly, David M Lewis, Lida Radfar, Donald U Stone, Joel M Guthridge, Judith A James, R Hal Scofield, Graham B Wiley, Jonathan D Wren, Patrick M Gaffney, Courtney G Montgomery, Kathy L Sivils, Astrid Rasmussen, A Darise Farris, Indra Adrianto, Christopher J Lessard
Publikováno v:
RMD open. 8(2)
ObjectiveSjögren’s disease (SjD) is an autoimmune disease characterised by inflammatory destruction of exocrine glands. Patients with autoantibodies to Ro/SSA (SjDRo+) exhibit more severe disease. Long non-coding RNAs (lncRNAs) are a functionally
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e3450542a5119125523232996309e11
https://pubmed.ncbi.nlm.nih.gov/36456101
https://pubmed.ncbi.nlm.nih.gov/36456101
Autor:
Prithvi Raj, Ekta Rai, Ran Song, Shaheen Khan, Benjamin E Wakeland, Kasthuribai Viswanathan, Carlos Arana, Chaoying Liang, Bo Zhang, Igor Dozmorov, Ferdicia Carr-Johnson, Mitja Mitrovic, Graham B Wiley, Jennifer A Kelly, Bernard R Lauwerys, Nancy J Olsen, Chris Cotsapas, Christine K Garcia, Carol A Wise, John B Harley, Swapan K Nath, Judith A James, Chaim O Jacob, Betty P Tsao, Chandrashekhar Pasare, David R Karp, Quan Zhen Li, Patrick M Gaffney, Edward K Wakeland
Publikováno v:
eLife, Vol 5 (2016)
Targeted sequencing of sixteen SLE risk loci among 1349 Caucasian cases and controls produced a comprehensive dataset of the variations causing susceptibility to systemic lupus erythematosus (SLE). Two independent disease association signals in the H
Externí odkaz:
https://doaj.org/article/9cb126754a5c4c41a78ee8db59f27c5a
Autor:
Yogesh K. Chutake, Christina Lam, Matthew Gilliam, Layne N. Rodden, Lauren A. Hauser, David A. Lynch, Sanjay I. Bidichandani, Kaitlyn M. Gilliam, Joel M. Gottesfeld, Graham B. Wiley, Elisabetta Soragni, Michael P. Anderson
Publikováno v:
Human Molecular Genetics
Friedreich ataxia (FRDA) is typically caused by homozygosity for an expanded GAA triplet-repeat in intron 1 of the FXN gene, which results in transcriptional deficiency via epigenetic silencing. Most patients are homozygous for alleles containing > 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d48becc41650ce92ac04e7430ae01ef6
https://doi.org/10.1093/hmg/ddaa267
https://doi.org/10.1093/hmg/ddaa267
Autor:
Matthew J. Miller, Graham B. Wiley
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 6, Pp 1829-1836 (2020)
Woodpeckers are found in nearly every part of the world and have been important for studies of biogeography, phylogeography, and macroecology. Woodpecker hybrid zones are often studied to understand the dynamics of introgression between bird species.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1314703589695f58f1555865c125eb47
https://doi.org/10.1534/g3.120.401059
https://doi.org/10.1534/g3.120.401059
Autor:
Satish Pasula, Graham B. Wiley, Patrick M. Gaffney, Richard Pelikan, Jennifer A. Kelly, Yao Fu, Mandi M. Wiley, Kandice L. Tessneer, Jaanam Gopalakrishnan
Publikováno v:
Arthritis & Rheumatology. 72:780-790
OBJECTIVE Genetic variants in the region of tumor necrosis factor-induced protein 3-interacting protein 1 (TNIP1) are associated with autoimmune disease and reduced TNIP1 gene expression. The aim of this study was to define the functional genetic mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c4ae87e20b21799a7936fb481057210
https://doi.org/10.1002/art.41188
https://doi.org/10.1002/art.41188
Autor:
Jennifer A. Kelly, Sai Ma, Richard Pelikan, Graham B. Wiley, Patrick M. Gaffney, David Murphy, Yao Fu, Caleb A. Lareau, Vinay K. Kartha, Jason D. Buenrostro
Publikováno v:
Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56323e83060c793d48b2dd263e805284
https://doi.org/10.1136/lupus-2021-lupus21century.91
https://doi.org/10.1136/lupus-2021-lupus21century.91
Autor:
Chase A. Brown, Kar Ming Fung, Nataliya Smith, Shannon Remerowski, Debra Saunders, Junyeong Jin, Michelle Zalles, Rheal A. Towner, Graham B. Wiley, Nadya Mamedova, Rafal Gulej, Kyusang Hwang, James Battiste, Megan R. Lerner, Junho Chung, Jadith Ziegler, Lincy Thomas, Jonathan D. Wren
Publikováno v:
Journal of Cellular and Molecular Medicine
Glioblastoma is an aggressive brain tumour found in adults, and the therapeutic approaches available have not significantly increased patient survival. Recently, we discovered that ELTD1, an angiogenic biomarker, is highly expressed in human gliomas.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72924fee4dde080262b1a1759a2d65f7
https://doi.org/10.1111/jcmm.14867
https://doi.org/10.1111/jcmm.14867