Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Graham A. D. Blyth"'
Autor:
Hani Boshra, Graham A. D. Blyth, Thang Truong, Andrea Kroeker, Pravesh Kara, Arshad Mather, David Wallace, Shawn Babiuk
Publikováno v:
Vaccines, Vol 12, Iss 7, p 805 (2024)
Capripoxviruses are the causative agents of sheeppox, goatpox, and lumpy skin disease (LSD) in cattle, which cause economic losses to the livestock industry in Africa and Asia. Capripoxviruses are currently controlled using several live attenuated va
Externí odkaz:
https://doaj.org/article/022093f4235043b79957039ae898a0a7
Autor:
Blanca E. Callejas, Graham A. D. Blyth, Nicholas Jendzjowsky, Arthur Wang, Anshu Babbar, Konstantin Koro, Richard J. A. Wilson, Margaret M. Kelly, Eduardo R. Cobo, Derek M. McKay
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The murine interleukin-4 treated macrophage (MIL4) exerts anti-inflammatory and pro-healing effects and has been shown to reduce the severity of chemical-induced colitis. Positing M(IL4) transfer as an anti-inflammatory therapy, the possibility of si
Externí odkaz:
https://doaj.org/article/251b4328e7ca45afa2a4d2fd7994eddd
Autor:
Ravi Holani, Anshu Babbar, Graham A. D. Blyth, Fernando Lopes, Humberto Jijon, Derek M. McKay, Morley D. Hollenberg, Eduardo R. Cobo
Publikováno v:
Gut Microbes, Vol 12, Iss 1 (2020)
We hypothesized that the antimicrobial peptide cathelicidin has a physiological role in regulating gut inflammatory homeostasis. We determined that cathelicidin synergizes with LPS to facilitate its internalization and signaling via endosomic TLR4 in
Externí odkaz:
https://doaj.org/article/ac13c2c2683f4f61b068423c553476e5
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Host defense peptides, abundantly secreted by colonic epithelial cells and leukocytes, are proposed to be critical components of an innate immune response in the colon against enteropathogenic bacteria, including Shigella spp., Salmonella spp., Clost
Externí odkaz:
https://doaj.org/article/79d582973e654c1780c6c8d2c34e08cb
Autor:
Konstantin Koro, Arthur Wang, Margaret M. Kelly, Blanca E. Callejas, Derek M. McKay, Richard J. A. Wilson, Eduardo R. Cobo, Nicholas G. Jendzjowsky, Graham A D Blyth, Anshu Babbar
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Frontiers in Immunology
The murine interleukin-4 treated macrophage (MIL4) exerts anti-inflammatory and pro-healing effects and has been shown to reduce the severity of chemical-induced colitis. Positing M(IL4) transfer as an anti-inflammatory therapy, the possibility of si
Autor:
Eduardo R. Cobo, Maia Solange Marin, Dominique Drouin, Anselmo Carlos Odeón, Ravi Holani, Graham A D Blyth
Publikováno v:
Cell and Tissue Research. 376:433-442
The intestinal mucosa contributes to frontline gut defenses by forming a barrier (physical and biochemical) and preventing the entry of pathogenic microbes. One innate role of the human colonic epithelium is to secrete cathelicidin, a peptide with br
Autor:
Graham A D Blyth, Anshu Babbar, Humberto Jijon, Ravi Holani, Derek M. McKay, Morley D. Hollenberg, Eduardo R. Cobo, Fernando Lopes
Publikováno v:
Gut Microbes
article-version (VoR) Version of Record
Gut Microbes, Vol 12, Iss 1 (2020)
article-version (VoR) Version of Record
Gut Microbes, Vol 12, Iss 1 (2020)
We hypothesized that the antimicrobial peptide cathelicidin has a physiological role in regulating gut inflammatory homeostasis. We determined that cathelicidin synergizes with LPS to facilitate its internalization and signaling via endosomic TLR4 in
Publikováno v:
Journal of Virology
Interferon-inducible transmembrane proteins (IFITMs) can restrict the entry of a wide range of viruses. IFITM3 localizes to endosomes and can potently restrict the replication of influenza A viruses (IAV) and several other viruses that also enter hos
Autor:
Graham A. D. Blyth, Ximena Fleming-Canepa, Alysson H. Blaine, Katharine E. Magor, Kristina Petkau, Domingo Miranzo Navarro, Megan R.W. Barber
Publikováno v:
Developmental and Comparative Immunology
Highlights • Avian genomes contain a smaller immune repertoire. • TLR8, RIG-I and downstream components are missing in chickens. • Birds are missing IgD, and ducks make a truncated IgY. • Chicken leukocyte Ig-like receptors are missing in duc