Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Graham A Bentley"'
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0183198 (2017)
Malaria, a disease endemic in many tropical and subtropical regions, is caused by infection of the erythrocyte by the apicomplexan parasite Plasmodium. Host-cell invasion is a complex process but two Plasmodium proteins, Apical Membrane Antigen 1 (AM
Externí odkaz:
https://doaj.org/article/f3d9d672727a4fb09f1c5715d7ed9876
Autor:
Frederick A. Saul, Brigitte Vulliez-Le Normand, Alexander Boes, Holger Spiegel, Clemens H.M. Kocken, Bart W. Faber, Graham A. Bentley
Publikováno v:
Journal of Structural Biology: X, Vol 10, Iss , Pp 100110- (2024)
Apical Membrane Antigen 1 (AMA1) plays a vital role in the invasion of the host erythrocyte by the malaria parasite, Plasmodium. It is thus an important target for vaccine and anti-malaria therapeutic strategies that block the invasion process. AMA1,
Externí odkaz:
https://doaj.org/article/e07f3fe089b443709f003b70b7311b82
Autor:
Micheline Guillotte, Alexandre Juillerat, Sébastien Igonet, Audrey Hessel, Stéphane Petres, Elodie Crublet, Cécile Le Scanf, Anita Lewit-Bentley, Graham A Bentley, Inès Vigan-Womas, Odile Mercereau-Puijalon
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0134292 (2015)
Adhesion of Plasmodium falciparum-infected red blood cells (iRBC) to human erythrocytes (i.e. rosetting) is associated with severe malaria. Rosetting results from interactions between a subset of variant PfEMP1 (Plasmodium falciparum erythrocyte memb
Externí odkaz:
https://doaj.org/article/cff3771abc2046d38bc0f9436991bc3e
Autor:
Bart W Faber, Khamisah Abdul Kadir, Roberto Rodriguez-Garcia, Edmond J Remarque, Frederick A Saul, Brigitte Vulliez-Le Normand, Graham A Bentley, Clemens H M Kocken, Balbir Singh
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0124400 (2015)
Infection with Plasmodium knowlesi, a zoonotic primate malaria, is a growing human health problem in Southeast Asia. P. knowlesi is being used in malaria vaccine studies, and a number of proteins are being considered as candidate malaria vaccine anti
Externí odkaz:
https://doaj.org/article/e10b9fc972d149b1ae2c819ead5f4200
Autor:
Brigitte Vulliez-Le Normand, Bart W Faber, Frederick A Saul, Marjolein van der Eijk, Alan W Thomas, Balbir Singh, Clemens H M Kocken, Graham A Bentley
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123567 (2015)
The malaria parasite Plasmodium knowlesi, previously associated only with infection of macaques, is now known to infect humans as well and has become a significant public health problem in Southeast Asia. This species should therefore be targeted in
Externí odkaz:
https://doaj.org/article/990ee2b45f2b45609f5d3921acc936b2
Autor:
Inès Vigan-Womas, Micheline Guillotte, Alexandre Juillerat, Audrey Hessel, Bertrand Raynal, Patrick England, Jacques H Cohen, Olivier Bertrand, Thierry Peyrard, Graham A Bentley, Anita Lewit-Bentley, Odile Mercereau-Puijalon
Publikováno v:
PLoS Pathogens, Vol 8, Iss 7, p e1002781 (2012)
The ABO blood group influences susceptibility to severe Plasmodium falciparum malaria. Recent evidence indicates that the protective effect of group O operates by virtue of reduced rosetting of infected red blood cells (iRBCs) with uninfected RBCs. R
Externí odkaz:
https://doaj.org/article/d0409c6651fb4a2d9ca02f49988aadf0
Autor:
Brigitte Vulliez-Le Normand, Michelle L Tonkin, Mauld H Lamarque, Susann Langer, Sylviane Hoos, Magali Roques, Frederick A Saul, Bart W Faber, Graham A Bentley, Martin J Boulanger, Maryse Lebrun
Publikováno v:
PLoS Pathogens, Vol 8, Iss 6, p e1002755 (2012)
Members of the phylum Apicomplexa, which include the malaria parasite Plasmodium, share many features in their invasion mechanism in spite of their diverse host cell specificities and life cycle characteristics. The formation of a moving junction (MJ
Externí odkaz:
https://doaj.org/article/291ea7a19b3f47198e71a11aee704baf
Autor:
Juan Carlos Pizarro, Ginette Boulot, Graham A Bentley, Karina A Gómez, Johan Hoebeke, Mireille Hontebeyrie, Mariano J Levin, Cristian R Smulski
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 5, Iss 11, p e1375 (2011)
Patients with Chronic Chagas' Heart Disease possess high levels of antibodies against the carboxyl-terminal end of the ribosomal P2ß protein of Trypanosoma cruzi (TcP2ß). These antibodies, as well as the murine monoclonal antibody (mAb) 17.2, recog
Externí odkaz:
https://doaj.org/article/6e608724de6844cdae7c66dd5579fbb0
Autor:
Inès Vigan-Womas, Micheline Guillotte, Alexandre Juillerat, Cindy Vallieres, Anita Lewit-Bentley, Adama Tall, Laurence Baril, Graham A Bentley, Odile Mercereau-Puijalon
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e16544 (2011)
The clonally variant Plasmodium falciparum PfEMP1 adhesin is a virulence factor and a prime target of humoral immunity. It is encoded by a repertoire of functionally differentiated var genes, which display architectural diversity and allelic polymorp
Externí odkaz:
https://doaj.org/article/b66eaeb47b1f4584836b810bf1c4af48
Autor:
Anand Srivastava, Stéphane Gangnard, Sébastien Dechavanne, Farroudja Amirat, Anita Lewit Bentley, Graham A Bentley, Benoît Gamain
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e20270 (2011)
Var2CSA, a key molecule linked with pregnancy-associated malaria (PAM), causes sequestration of Plasmodium falciparum infected erythrocytes (PEs) in the placenta by adhesion to chondroitin sulfate A (CSA). Var2CSA possesses a 300 kDa extracellular re
Externí odkaz:
https://doaj.org/article/66c2e98ae51745d387e6c420e2cdcbfb