Zobrazeno 1 - 10
of 310
pro vyhledávání: '"Graham A, Hitman"'
Autor:
B. William Ogunkolade, Antonysunil Adaikalakoteswari, Shirleny Romualdo Cardoso, Rob Lowe, Nisha Patel, Vardhman Rakyan, Sarah Finer, Martin Wabitsch, Ponnusamy Saravanan, Gyanendra Tripathi, Elena Bochukova, Graham A Hitman
Publikováno v:
Epigenetics, Vol 17, Iss 10, Pp 1219-1233 (2022)
Vitamin B12 has multiple biochemical functions including in the one-carbon cycle generating a methyl group for DNA methylation, and metabolism of fatty acids and amino acids to generate energy via the citric acid cycle. The aim of our study was to us
Externí odkaz:
https://doaj.org/article/da875f7227f04099ad63049ddd7f3934
Autor:
Shirleny R Cardosa, B. William Ogunkolade, Rob Lowe, Emanuel Savage, Charles A Mein, Barbara J Boucher, Graham A Hitman
Publikováno v:
BMC Endocrine Disorders, Vol 21, Iss 1, Pp 1-11 (2021)
Abstract Background Betel-nut consumption is the fourth most common addictive habit globally and there is good evidence linking the habit to obesity, type 2 diabetes (T2D) and the metabolic syndrome. The aim of our pilot study was to identify gene ex
Externí odkaz:
https://doaj.org/article/0e6031ae7c5145e1967a4d3e913bcf7d
Autor:
Stella Trompet, Iris Postmus, Helen R. Warren, Raymond Noordam, Roelof A. J. Smit, Elizabeth Theusch, Xiaohui Li, Benoit Arsenault, Daniel I. Chasman, Graham A. Hitman, Patricia B. Munroe, Jerome I. Rotter, Bruce M. Psaty, Mark J. Caulfield, Ron M. Krauss, Adrienne L. Cupples, Wouter J. Jukema
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2022)
Background: The pharmacogenetic effect on cardiovascular disease reduction in response to statin treatment has only been assessed in small studies. In a pharmacogenetic genome wide association study (GWAS) analysis within the Genomic Investigation of
Externí odkaz:
https://doaj.org/article/a2d8d3a7c59940099b7735739ad32258
Autor:
Bishwajit Bhowmik, Tasnima Siddique, Anindita Majumder, Ibrahimu Mdala, Israt A. Hossain, Zahid Hassan, Ishrat Jahan, Nayla Cristina do V. Moreira, Abdul Alim, Abdul Basit, Graham A. Hitman, Abul Kalam A. Khan, Akhtar Hussain
Publikováno v:
BMC Pregnancy and Childbirth, Vol 19, Iss 1, Pp 1-14 (2019)
Abstract Background To assess the maternal characteristics and nutritional status according to body mass index (BMI) at 6–14 weeks of gestation and to examine the relationship between maternal nutritional status in early pregnancy and its impact on
Externí odkaz:
https://doaj.org/article/172d3889078547de8b40ee3e594ac89c
Autor:
Lauren A. Callender, Elizabeth C. Carroll, Conor Garrod-Ketchley, Johannes Schroth, Jonas Bystrom, Victoria Berryman, Melanie Pattrick, Desiree Campbell-Richards, Gillian A. Hood, Graham A. Hitman, Sarah Finer, Sian M. Henson
Publikováno v:
Frontiers in Aging, Vol 2 (2021)
Mitochondrial health and cellular metabolism can heavily influence the onset of senescence in T cells. CD8+ EMRA T cells exhibit mitochondrial dysfunction and alterations to oxidative phosphorylation, however, the metabolic properties of senescent CD
Externí odkaz:
https://doaj.org/article/3d785a4ee8d34e03b1e989f0b39f8d14
Autor:
Charlie Foster, Tracy Roberts, Stamatina Iliodromiti, Lucilla Poston, Shakila Thangaratinam, Helena J Teede, John Allotey, Dyuti Coomar, Nicola Heslehurst, Graham A Hitman, Jonathan M Hazlehurst, Frances Austin, Ngawai Moss, Sharon A Simpson
Publikováno v:
BMJ Open, Vol 11, Iss 6 (2021)
Introduction Mothers with gestational diabetes mellitus (GDM) are at increased risk of pregnancy-related complications and developing type 2 diabetes after delivery. Diet and physical activity-based interventions may prevent GDM, but variations in po
Externí odkaz:
https://doaj.org/article/fc43c7e7a2f245bc8da1fede56e91e41
Autor:
Bassel H Al Wattar, Julie Dodds, Anna Placzek, Lee Beresford, Eleni Spyreli, Amanda Moore, Francisco J Gonzalez Carreras, Frances Austin, Nilaani Murugesu, Tessa J Roseboom, Maira Bes-Rastrollo, Graham A Hitman, Richard Hooper, Khalid S Khan, Shakila Thangaratinam, ESTEEM study group
Publikováno v:
PLoS Medicine, Vol 16, Iss 7, p e1002857 (2019)
BackgroundPregnant women with metabolic risk factors are at high risk of complications. We aimed to assess whether a Mediterranean-style diet reduces adverse pregnancy outcomes in high-risk women.Methods and findingsWe conducted a multicentre randomi
Externí odkaz:
https://doaj.org/article/26e5bbba8fc8479fa776647a61ff49db
Autor:
Shirleny Cardoso, Sarah Finer, Graham A. Hitman, Elena G. Bochukova, Gyanendra Tripathi, Ponnusamy Saravanan, Robert Lowe, Vardhman K. Rakyan, Nisha Patel, Antonysunil Adaikalakoteswari, Martin Wabitsch, B. William Ogunkolade
Publikováno v:
Epigenetics. 17:1219-1233
Vitamin B12 has multiple biochemical functions including in the one-carbon cycle generating a methyl group for DNA methylation, and metabolism of fatty acids and amino acids to generate energy via the citric acid cycle. The aim of our study was to us
Autor:
Louise A. Beveridge, Faisel Khan, Allan D. Struthers, Jane Armitage, Ilaria Barchetta, Iain Bressendorff, Maria Gisella Cavallo, Robert Clarke, Rinkoo Dalan, Gavin Dreyer, Adam D. Gepner, Nita G. Forouhi, Ryan A. Harris, Graham A. Hitman, Thomas Larsen, Rajesh Khadgawat, Peter Marckmann, Frank H. Mose, Stefan Pilz, Alexandra Scholze, Marina Shargorodsky, Seth I. Sokol, Hans Stricker, Carmine Zoccali, Miles D. Witham
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 11 (2018)
BackgroundLow 25‐hydroxyvitamin D levels are associated with an increased risk of cardiovascular events, but the effect of vitamin D supplementation on markers of vascular function associated with major adverse cardiovascular events is unclear. Met
Externí odkaz:
https://doaj.org/article/3d40ee94311444d7a9c826d03cd25b8c
Autor:
Musarrat Riaz, Fareeha Shaikh, Asher Fawwad, Rubina Hakeem, A. Samad Shera, Graham A. Hitman, Bishwajit Bhowmik, Nayla Christina do Vale Moreira, Abdul Basit, Akhtar Hussain
Publikováno v:
Journal of Diabetes Research, Vol 2018 (2018)
Objective. To explore the impact of maternal body weight on maternal nutrition and micronutrient status in early pregnancy and potential impact on metabolic status in newborns. Methodology. The EU FP7 project GIFTS was conducted from Jan 2012 to May
Externí odkaz:
https://doaj.org/article/d6f5f5bc46ae496aa992863609e0b408