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Antibodies directed to α6β4 highlight the adhesive and signaling functions of the integrin in breast cancer cell lines

Autor: Gabarra, Veronica, Cho, Samuel, Ramirez, Miriam, Ren, Yan, Chen, Ling Ling, Cheung, Anne, Cao, Xianjun, Rennard, Rachel, Unruh, Kelsey R., Graff, Christilyn P., Browning, Beth, Huet, Heather, McLachlan, Karen

Publikováno v: Cancer Biology and Therapy; March 2010, Vol. 9 Issue: 6 p437-445, 9p

AIntibody: an experimentally validated in silico antibody discovery design challenge.

Autor: Erasmus MF; Specifica LLC, an IQVIA business, Santa Fe, USA. mfrank.erasmus@iqvia.com., Spector L; Specifica LLC, an IQVIA business, Santa Fe, USA., Ferrara F; Specifica LLC, an IQVIA business, Santa Fe, USA., DiNiro R; Specifica LLC, an IQVIA business, Santa Fe, USA., Pohl TJ; Specifica LLC, an IQVIA business, Santa Fe, USA., Perea-Schmittle K; Specifica LLC, an IQVIA business, Santa Fe, USA., Wang W; University of California, San Diego, USA., Tessier PM; University of Michigan, Ann Arbor, USA., Richardson C; GENEWIZ from Azenta Life Sciences, South Plainfield, USA., Turner L; GENEWIZ from Azenta Life Sciences, South Plainfield, USA., Kumar S; GENEWIZ from Azenta Life Sciences, South Plainfield, USA., Bedinger D; Carterra, Salt Lake City, USA., Sormanni P; University of Cambridge, Cambridge, UK., Fernández-Quintero ML; Scripps Research Institute, San Diego, CA, USA., Ward AB; Scripps Research Institute, San Diego, CA, USA., Loeffler JR; Scripps Research Institute, San Diego, CA, USA., Swanson OM; Scripps Research Institute, San Diego, CA, USA., Deane CM; University of Oxford, Oxford, UK., Raybould MIJ; University of Oxford, Oxford, UK., Evers A; Merck KGaA, Darmstadt, Germany., Sellmann C; Merck KGaA, Darmstadt, Germany., Bachas S; Evolutionary Scale, San Francisco, USA., Ruffolo J; Profluent Bio, Berkeley, USA., Nastri HG; Incyte, Inc, Wilmington, USA., Ramesh K; Incyte, Inc, Wilmington, USA., Sørensen J; OpenEye, Cadence Molecular Sciences, Santa Fe, USA., Croasdale-Wood R; Astrazeneca, Cambridge, UK., Hijano O; Sanofi, Inc, Cambridge, USA., Leal-Lopes C; Sanofi, Inc, Cambridge, USA., Shahsavarian M; Eli Lilly, San Diego, USA., Qiu Y; Sanofi, Inc, Cambridge, USA., Marcatili P; Novo Nordisk, A/S, Bagsværd, Denmark., Vernet E; Novo Nordisk, A/S, Bagsværd, Denmark., Akbar R; Novo Nordisk, A/S, Bagsværd, Denmark., Friedensohn S; Alloy Therapeutics, Basel, Switzerland., Wagner R; Bonito Biosciences, Waltham, USA., Kurella VB; Takeda, Inc, Cambridge, USA., Malhotra S; Takeda, Inc, Cambridge, USA., Kumar S; Takeda, Inc, Cambridge, USA., Kidger P; Cradle Bio, Zürich, Switzerland., Almagro JC; GlobalBio, Inc., Cambridge, MA, USA., Furfine E; Mosaic Biosciences, Boulder, USA., Stanton M; Mosaic Biosciences, Boulder, USA., Graff CP; Mosaic Biosciences, Boulder, USA., Villalba SD; Bayer AG, Leverkusen, Germany., Tomszak F; Bayer AG, Leverkusen, Germany., Teixeira AAR; Institute for Protein Innovation, Boston, USA., Hopkins E; Sapidyne Instruments, Inc. & GmbH, Boise, USA., Dovner M; Sapidyne Instruments, Inc. & GmbH, Boise, USA., D'Angelo S; Specifica LLC, an IQVIA business, Santa Fe, USA., Bradbury ARM; Specifica LLC, an IQVIA business, Santa Fe, USA. andrew.bradbury@iqvia.com.

Publikováno v: Nature biotechnology [Nat Biotechnol] 2024 Nov; Vol. 42 (11), pp. 1637-1642.