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Combined Administration of Metformin and Amprolium to Rats Affects Metabolism of Free Amino Acids in the Brain, Altering Behavior, and Heart Rate.

Autor: Graf AV; Belozersky Institute of Physicochemical Biology, Lomonosov Moscow State University, Moscow, 119234, Russia.; Faculty of Biology, Lomonosov Moscow State University, Moscow, 119234, Russia., Artiukhov AV; Belozersky Institute of Physicochemical Biology, Lomonosov Moscow State University, Moscow, 119234, Russia.; Department of Biochemistry, Sechenov Medical University, Moscow, 105043, Russia., Solovjeva ON; Belozersky Institute of Physicochemical Biology, Lomonosov Moscow State University, Moscow, 119234, Russia., Ksenofontov AL; Belozersky Institute of Physicochemical Biology, Lomonosov Moscow State University, Moscow, 119234, Russia., I Bunik V; Belozersky Institute of Physicochemical Biology, Lomonosov Moscow State University, Moscow, 119234, Russia. bunik@belozersky.msu.ru.; Department of Biochemistry, Sechenov Medical University, Moscow, 105043, Russia.; Faculty of Bioengineering and Bioinformatics, Lomonosov Moscow State University, Moscow, 119991, Russia.

Publikováno v: Biochemistry. Biokhimiia [Biochemistry (Mosc)] 2024 Oct; Vol. 89 (10), pp. 1692-1710.

Pharmacological Doses of Thiamine Benefit Patients with the Charcot-Marie-Tooth Neuropathy by Changing Thiamine Diphosphate Levels and Affecting Regulation of Thiamine-Dependent Enzymes.

Autor: Artiukhov AV; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, 119234, Russia.; Department of Biochemistry, Sechenov University, Moscow, 119991, Russia., Solovjeva ON; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, 119234, Russia., Balashova NV; Faculty of Advanced Medicine, Vladimirsky Moscow Regional Research and Clinical Institute, Moscow, 129110, Russia.; Faculty of Continuing Medical Education, RUDN Medical Institute, Moscow, 117198, Russia., Sidorova OP; Department of Neurology, Vladimirsky Moscow Regional Research and Clinical Institute, Moscow, 129110, Russia., Graf AV; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, 119234, Russia.; Faculty of Biology, Lomonosov Moscow State University, Moscow, 119234, Russia., Bunik VI; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, 119234, Russia. bunik@belozersky.msu.ru.; Department of Biochemistry, Sechenov University, Moscow, 119991, Russia.; Faculty of Bioengineering and Bioinformatics, Lomonosov Moscow State University, Moscow, 119234, Russia.

Publikováno v: Biochemistry. Biokhimiia [Biochemistry (Mosc)] 2024 Jul; Vol. 89 (7), pp. 1161-1182.

Pentylenetetrazole-Induced Seizures Are Increased after Kindling, Exhibiting Vitamin-Responsive Correlations to the Post-Seizures Behavior, Amino Acids Metabolism and Key Metabolic Regulators in the Rat Brain.

Autor: Aleshin VA; A.N. Belozersky Institute of Physicochemical Biology, Lomonosov Moscow State University, 119991 Moscow, Russia.; Department of Biochemistry, Sechenov University, Trubetskaya, 8, Bld. 2, 119991 Moscow, Russia., Graf AV; Faculty of Biology, Lomonosov Moscow State University, 119234 Moscow, Russia.; Faculty of Nano-, Bio-, Informational, Cognitive and Socio-Humanistic Sciences and Technologies at Moscow Institute of Physics and Technology, Maximova Street 4, 123098 Moscow, Russia., Artiukhov AV; A.N. Belozersky Institute of Physicochemical Biology, Lomonosov Moscow State University, 119991 Moscow, Russia.; Department of Biochemistry, Sechenov University, Trubetskaya, 8, Bld. 2, 119991 Moscow, Russia., Ksenofontov AL; A.N. Belozersky Institute of Physicochemical Biology, Lomonosov Moscow State University, 119991 Moscow, Russia., Zavileyskiy LG; Faculty of Bioengineering and Bioinformatics, Lomonosov Moscow State University, 119991 Moscow, Russia., Maslova MV; Faculty of Biology, Lomonosov Moscow State University, 119234 Moscow, Russia., Bunik VI; A.N. Belozersky Institute of Physicochemical Biology, Lomonosov Moscow State University, 119991 Moscow, Russia.; Department of Biochemistry, Sechenov University, Trubetskaya, 8, Bld. 2, 119991 Moscow, Russia.; Faculty of Bioengineering and Bioinformatics, Lomonosov Moscow State University, 119991 Moscow, Russia.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2023 Aug 03; Vol. 24 (15). Date of Electronic Publication: 2023 Aug 03.

Phosphonate Inhibitors of Pyruvate Dehydrogenase Perturb Homeostasis of Amino Acids and Protein Succinylation in the Brain.

Autor: Artiukhov AV; Department of Biokinetics, A. N. Belozersky Institute of Physicochemical Biology, Lomonosov Moscow State University, 119234 Moscow, Russia.; Department of Biochemistry, Sechenov University, 105043 Moscow, Russia., Aleshin VA; Department of Biokinetics, A. N. Belozersky Institute of Physicochemical Biology, Lomonosov Moscow State University, 119234 Moscow, Russia.; Department of Biochemistry, Sechenov University, 105043 Moscow, Russia., Karlina IS; Department of Clinical Medicine, Sechenov University, 105043 Moscow, Russia., Kazantsev AV; Department of Biokinetics, A. N. Belozersky Institute of Physicochemical Biology, Lomonosov Moscow State University, 119234 Moscow, Russia.; Faculty of Chemistry, Lomonosov Moscow State University, 119234 Moscow, Russia., Sibiryakina DA; Faculty of Biology, Lomonosov Moscow State University, 119234 Moscow, Russia., Ksenofontov AL; Department of Biokinetics, A. N. Belozersky Institute of Physicochemical Biology, Lomonosov Moscow State University, 119234 Moscow, Russia., Lukashev NV; Faculty of Chemistry, Lomonosov Moscow State University, 119234 Moscow, Russia., Graf AV; Department of Biokinetics, A. N. Belozersky Institute of Physicochemical Biology, Lomonosov Moscow State University, 119234 Moscow, Russia.; Faculty of Biology, Lomonosov Moscow State University, 119234 Moscow, Russia., Bunik VI; Department of Biokinetics, A. N. Belozersky Institute of Physicochemical Biology, Lomonosov Moscow State University, 119234 Moscow, Russia.; Department of Biochemistry, Sechenov University, 105043 Moscow, Russia.; Faculty of Bioengineering and Bioinformatics, Lomonosov Moscow State University, 119234 Moscow, Russia.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2022 Oct 29; Vol. 23 (21). Date of Electronic Publication: 2022 Oct 29.