Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Graeme L. Hickey"'
Autor:
Michael Böhm, Martin Fahy, Graeme L. Hickey, Stuart Pocock, Sandeep Brar, Vanessa DeBruin, Michael A. Weber, Felix Mahfoud, David E. Kandzari
Publikováno v:
Contemporary Clinical Trials Communications, Vol 23, Iss , Pp 100818- (2021)
Background: The SPYRAL HTN-OFF MED Pivotal trial demonstrated that RDN was efficacious compared to a sham control. The underlying model was an extension of the analysis of covariance (ANCOVA) model, adjusted for baseline blood pressure (BP), and allo
Externí odkaz:
https://doaj.org/article/5505195d4541437394f38f966b687f36
Publikováno v:
BMC Medical Research Methodology, Vol 18, Iss 1, Pp 1-14 (2018)
Abstract Background Joint modelling of longitudinal and time-to-event outcomes has received considerable attention over recent years. Commensurate with this has been a rise in statistical software options for fitting these models. However, these tool
Externí odkaz:
https://doaj.org/article/10626952332e49cb95a61c6b294690fa
Autor:
Brian R. Lindman, Kashish Goel, Javier Bermejo, Joshua Beckman, Jared O'Leary, Colin M. Barker, Clayton Kaiser, João L. Cavalcante, Sammy Elmariah, Jian Huang, Graeme L. Hickey, David H. Adams, Jeffrey J. Popma, Michael J. Reardon
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 21 (2019)
Background Blood pressure (BP) guidelines for patients with aortic stenosis or a history of aortic stenosis treated with aortic valve replacement (AVR) match those in the general population, but this extrapolation may not be warranted. Methods and Re
Externí odkaz:
https://doaj.org/article/ea57cd6e0e8a4437bdec0c10f48f9684
Publikováno v:
BMC Medical Research Methodology, Vol 16, Iss 1, Pp 1-15 (2016)
Abstract Background Available methods for the joint modelling of longitudinal and time-to-event outcomes have typically only allowed for a single longitudinal outcome and a solitary event time. In practice, clinical studies are likely to record multi
Externí odkaz:
https://doaj.org/article/429170373d2646f38fed9f0b952d1e66
Publikováno v:
Journal of Biopharmaceutical Statistics. 33:77-89
Clinical studies are generally required to characterize the accuracy of new diagnostic tests. In some cases, historical data are available from a predicate device, which is directly relevant to the new test. If this data can be appropriately incorpor
Autor:
Michael Weber, Stuart J. Pocock, Michael Böhm, David E. Kandzari, Giuseppina Lamberti, Felix Mahfoud, Sidney Cohen, Graeme L. Hickey, Martin Fahy
Publikováno v:
EuroIntervention. 16:e1496-e1502
AIMS Multiple endpoints with varying clinical relevance are available to establish the efficacy of device-based treatments. Given the variance among blood pressure measures and medication changes in hypertension trials, we performed a win ratio analy
Autor:
Douglas A. Hettrick, Raymond R. Townsend, Andrew S.P. Sharp, Graeme L. Hickey, Peter J. Blankenstijn, Giuseppe Mancia, Michael Böhm, Joachim Weil, Antony Walton
Publikováno v:
EuroIntervention. 16:89-96
Aims We aimed to estimate the rate of renal artery adverse events following renal denervation with the most commonly applied radiofrequency catheter system based on a comprehensive review of published reports. Methods and results We reviewed 50 publi
Autor:
Michael G. Moront, Robert J.M. Klautz, Neil J. Weissman, Michael J. Reardon, Rob A.F. De Lind Van Wijngaarden, Joseph F. Sabik, Stuart J. Head, Graeme L. Hickey, Vivek Rao, Arie Pieter Kappetein, Michiel D. Vriesendorp
Publikováno v:
European Heart Journal Cardiovascular Imaging
European Heart Journal-Cardiovascular Imaging, 21(10), 1116-1122. OXFORD UNIV PRESS
European heart journal. Cardiovascular Imaging, 21(10), 1116-1122. Oxford University Press
European Heart Journal-Cardiovascular Imaging, 21(10), 1116-1122. OXFORD UNIV PRESS
European heart journal. Cardiovascular Imaging, 21(10), 1116-1122. Oxford University Press
Aims Indexed effective orifice area (EOAi) charts are used to determine the likelihood of prosthesis–patient mismatch (PPM) after aortic valve replacement (AVR). The aim of this study is to validate whether these EOAi charts, based on echocardiogra
Autor:
Michael Böhm, Konstantinos Tsioufis, Sandeep Brar, Roland E. Schmieder, Vanessa DeBruin, Felix Mahfoud, Kazuomi Kario, Stuart J. Pocock, David E. Kandzari, Martin Fahy, Graeme L. Hickey, Michael A. Weber, Raymond R. Townsend
Publikováno v:
Clinical Research in Cardiology
Background The SPYRAL HTN clinical trial program was initiated with two 80-patient pilot studies, SPYRAL HTN-OFF MED and SPYRAL HTN-ON MED, which provided biological proof of principle that renal denervation has a blood pressure-lowering effect versu
Publikováno v:
Interactive Cardiovascular and Thoracic Surgery, 28(1), 1-8. Oxford University Press
Hickey, G L, Kontopantelis, E, Takkenberg, J J M & Beyersdorf, F 2018, ' Statistical primer : checking model assumptions with regression diagnostics ', Interactive cardiovascular and thoracic surgery . https://doi.org/10.1093/icvts/ivy207
Hickey, G L, Kontopantelis, E, Takkenberg, J J M & Beyersdorf, F 2018, ' Statistical primer : checking model assumptions with regression diagnostics ', Interactive cardiovascular and thoracic surgery . https://doi.org/10.1093/icvts/ivy207
Regression modelling is an important statistical tool frequently utilized by cardiothoracic surgeons. However, these models-including linear, logistic and Cox proportional hazards regression-rely on certain assumptions. If these assumptions are viola