Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Graeme J., Nicholson"'
Benzoxacystol, a benzoxazine-type enzyme inhibitor from the deep-sea strain Streptomyces sp. NTK 935
Autor:
Kathrin Schneider, Graeme J. Nicholson, Christina Bruntner, Hans-Peter Fiedler, Elisabeth Irran, Heidi Zinecker, Johannes F. Imhoff, Roderich D. Süssmuth, Alan T. Bull, Jonny Nachtigall, Michael Goodfellow
Publikováno v:
The Journal of Antibiotics. 64:453-457
Benzoxacystol, a new 1,4-benzoxazine-type metabolite, was produced by strain NTK 935, a marine member of the Streptomyces griseus 16S rRNA clade, isolated from deep-sea sediment collected from the Canary Basin. The structure of benzoxacystol was dete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc067cb192b11fc4ec44cde19453056f
https://doi.org/10.1038/ja.2011.26
https://doi.org/10.1038/ja.2011.26
Autor:
Graeme J. Nicholson, Falko E. Wolter, Roderich D. Süssmuth, Brian P. Davies, Elke Socher, Oliver Seitz, Kathrin Schneider
Publikováno v:
Organic Letters. 11:2804-2807
The total synthesis of the natural occurring polyamides proximicin A-C (3-5) has been accomplished. A short and efficient synthesis of a thus far unknown 4-amino-2-furan carboxylic acid was developed. Furthermore, this unique heterocyclic gamma-amino
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::084f3c1108f888ce153f88169f64c8de
https://doi.org/10.1021/ol901003p
https://doi.org/10.1021/ol901003p
Autor:
Michael Goodfellow, James E. M. Stach, Claudia Hohmann, Graeme J. Nicholson, Johannes F. Imhoff, Marco Krämer, Roselyn Brown, Alan T. Bull, Roderich D. Süssmuth, Hans-Peter Fiedler, Amanda Jones, Winfried Beil, Christina Bruntner, Kathrin Schneider, Elisabeth Irran
Publikováno v:
Journal of Antibiotics, 62 . pp. 99-104.
Caboxamycin, a new benzoxazole antibiotic, was detected by HPLC-diode array screening in extracts of the marine strain Streptomyces sp. NTK 937, which was isolated from deep-sea sediment collected in the Canary Basin. The structure of caboxamycin was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e56b38c1f41f61e6a8a04ede8226cae4
https://doi.org/10.1038/ja.2008.24
https://doi.org/10.1038/ja.2008.24
Autor:
Johannes F. Imhoff, Marco Krämer, Graeme J. Nicholson, Hans-Peter Fiedler, Kathrin Schneider, Roderich D. Süssmuth, Roselyn Brown, Amanda Jones, Christina Bruntner, Michael Goodfellow, Claudia Hohmann
Publikováno v:
The Journal of Antibiotics. 62:75-79
Albidopyrone, a new alpha-pyrone-containing secondary metabolite, was produced by Streptomyces sp. NTK 227, a strain isolated from Atlantic Ocean sediment and found to be a member of the Streptomyces albidoflavus 16S rRNA gene clade. The structure of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd030f4fae584f627cb70becbe805c0f
https://doi.org/10.1038/ja.2008.15
https://doi.org/10.1038/ja.2008.15
Autor:
Ellen Graf, Simone Keller, Steffen Borden, Fiona M. Stainsby, Graeme J. Nicholson, Michael Goodfellow, Roderich D. Süssmuth, Hans-Peter Fiedler, Kathrin Schneider, Elisabeth Irran
Publikováno v:
The Journal of Antibiotics. 61:356-364
Bendigoles A approximately C are the first secondary metabolites to be isolated from a member of the actinomycete genus Gordonia. They were detected in a culture filtrate extract of Gordonia australis Acta 2299 by HPLC-diode array analysis and charac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1aac9293ca5ff0e3767f81a6cb74839b
https://doi.org/10.1038/ja.2008.50
https://doi.org/10.1038/ja.2008.50
Autor:
Winfried Beil, Simone Keller, Lars Röglin, Christina Bruntner, Oliver Seitz, Julia Riedlinger, Hans-Peter Fiedler, Kathrin Schneider, Falko E. Wolter, Graeme J. Nicholson, Roderich D. Süssmuth
Publikováno v:
Angewandte Chemie. 120:3302-3305
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8f4644d5754717234860fea7a2f7f02
https://doi.org/10.1002/ange.200705295
https://doi.org/10.1002/ange.200705295
Autor:
Simone Keller, Hans-Peter Fiedler, Carmen Drahl, Erik J. Sorensen, Roderich D. Süssmuth, Graeme J. Nicholson
Publikováno v:
The Journal of Antibiotics. 60:391-394
Abyssomicin C is a complex polyketide-type antibiotic and the first natural inhibitor of the p-aminobenzoate biosynthesis produced by the marine Verrucosispora strain AB-18-032. We have now isolated three novel naturally produced abyssomicins, among
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef6e65f542b4c093139698f1769e07ef
https://doi.org/10.1038/ja.2007.54
https://doi.org/10.1038/ja.2007.54
Autor:
Markus Ströbele, Amanda Jones, Roderich D. Süssmuth, Winfried Beil, Ellen Graf, Kathrin Schneider, Graeme J. Nicholson, Michael Goodfellow, Hans-Peter Fiedler
Publikováno v:
The Journal of Antibiotics. 60:277-284
Two new aminophenoxazinone compounds with antitumor activity, elloxazinone A and B, were isolated from the culture filtrate of Streptomyces griseus Acta 2871. Their chemical structures were determined by mass spectrometry, NMR spectroscopy and X-ray
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f075f053b00fc500a3421504de2a4b15
https://doi.org/10.1038/ja.2007.35
https://doi.org/10.1038/ja.2007.35
Publikováno v:
Chirality. 19:401-414
Whereas the determination of high enantiomeric fractions (EF) of chi- ral compounds is very well established, the accurate determination of small deviations from racemic compositions has not yet received much attention despite its relevance to studie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d10263853b8dd8227b449195873f788
https://doi.org/10.1002/chir.20390
https://doi.org/10.1002/chir.20390
Autor:
Andreas Peschel, Graeme J. Nicholson, Iris Fedtke, Thomas P. Kohler, Diana Mader, Ulrich Zähringer, Friedrich Götz, Katja Henseler, Raja Biswas, Hermann Moll
Publikováno v:
Molecular Microbiology
Many Gram-positive bacteria produce lipoteichoic acid (LTA) polymers whose physiological roles have remained a matter of debate because of the lack of LTA-deficient mutants. The ypfP gene responsible for biosynthesis of a glycolipid found in LTA was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c922b969efca18944f1bf23ffcd96cd4
http://europepmc.org/articles/PMC2169524
http://europepmc.org/articles/PMC2169524