Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Graeme J M, Alexander"'
Autor:
Phaedra M Tachtatzis, Aileen Marshall, Aloysious Arvinthan, Suman Verma, Sue Penrhyn-Lowe, Marianna Mela, Cinzia Scarpini, Susan E Davies, Nicholas Coleman, Graeme J M Alexander
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0127511 (2015)
BackgroundChronic Hepatitis B virus (HBV) infection can lead to the development of chronic hepatitis, cirrhosis and hepatocellular carcinoma. We hypothesized that HBV might accelerate hepatocyte ageing and investigated the effect of HBV on hepatocyte
Externí odkaz:
https://doaj.org/article/890fd41d4e1e47a9a387e1ab2f3df2ad
Autor:
Annie Y Chen, Matthew Hoare, Arun N Shankar, Michael Allison, Graeme J M Alexander, Tomasz I Michalak
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0140312 (2015)
Hepatitis C virus (HCV) frequently causes chronic hepatitis, while spontaneous recovery from infection is infrequent. Persistence of HCV after self-limited (spontaneous) resolution of hepatitis C was rarely investigated. The current study aimed to as
Externí odkaz:
https://doaj.org/article/779f3ea72d814e2f9b0adf57ebfdaa1e
Autor:
Phaedra M Tachtatzis, Aileen Marshall, Aloysious Aravinthan, Suman Verma, Sue Penrhyn-Lowe, Marianna Mela, Cinzia Scarpini, Susan E Davies, Nicholas Coleman, Graeme J M Alexander
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0134315 (2015)
Externí odkaz:
https://doaj.org/article/b3009ddeb526402fa50d077775c956da
Autor:
Aloysious Aravinthan, Giada Pietrosi, Matthew Hoare, James Jupp, Aileen Marshall, Clare Verrill, Susan Davies, Adrian Bateman, Nick Sheron, Michael Allison, Graeme J M Alexander
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e72904 (2013)
Background and aimAlcohol-related liver disease (ALD) remains a leading cause of liver-related morbidity and mortality. Age, fibrosis stage, MELD score and continued alcohol consumption predict outcome in everyday clinical practice. In previous studi
Externí odkaz:
https://doaj.org/article/f7baa89d77754508aaf5a78aa3fd829b
Autor:
Gordon M Daly, Nick Bexfield, Judith Heaney, Sam Stubbs, Antonia P Mayer, Anne Palser, Paul Kellam, Nizar Drou, Mario Caccamo, Laurence Tiley, Graeme J M Alexander, William Bernal, Jonathan L Heeney
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28879 (2011)
Here we describe a virus discovery protocol for a range of different virus genera, that can be applied to biopsy-sized tissue samples. Our viral enrichment procedure, validated using canine and human liver samples, significantly improves viral read c
Externí odkaz:
https://doaj.org/article/97b47803bd37404a99540a959be53751
Publikováno v:
Alcohol and Alcoholism. 34:55-58
This paper describes a 1-year follow-up study examining whether hospital ward doctors and nurses continue to take quantitative alcohol histories and provide brief intervention to problem drinkers on general medical wards after the introduction of a s
Autor:
John M. Goldman, Martyn J. Carter, Mark Walport, Reinhard Würzner, Marina Botto, Michael A. Naughton, Graeme J. M. Alexander
Publikováno v:
European Journal of Immunology. 26:2108-2112
Many cells types can produce complement component C7, although the major site of C7 synthesis is unknown. Conversion from recipient to donor allotype following organ transplantation has demonstrated the synthetic sites of several complement proteins,
Autor:
William, Gelson, Matthew, Hoare, Sarah, Vowler, Arun, Shankar, Paul, Gibbs, Arne N, Akbar, Graeme J M, Alexander
Publikováno v:
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. 16(5)
Immune senescence is the normal process whereby the human immune system ages, but becomes less effective. We investigated whether liver transplant recipients have features of immune senescence. Lymphocytes from 97 liver transplant recipients with est
Autor:
Aileen E, Marshall, Simon M, Rushbrook, Sarah L, Vowler, Christopher R, Palmer, R Justin, Davies, Paul, Gibbs, Susan E, Davies, Nicholas, Coleman, Graeme J M, Alexander
Publikováno v:
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. 16(3)
The selection of patients with hepatocellular carcinoma for liver transplantation is currently based on the size and number of tumors to minimize the risk of recurrence. These criteria measure tumor bulk but may not reflect tumor behavior accurately.
Publikováno v:
Methods in Molecular Biology ISBN: 9781588299703
The HCV genome is highly heterogeneous; more and more genotypes, each with several distinct subtypes, are being identified around the world. Knowledge of genotype is important for planning of treatment regimes, whereas subtype identification is usefu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a645564d8075fdbc986d9b22d6c714f
https://doi.org/10.1007/978-1-59745-394-3_5
https://doi.org/10.1007/978-1-59745-394-3_5