Výsledky vyhledávání - "Graeme Hewson"

Rapid absorption of sumatriptan powder and effects on glyceryl trinitrate model of headache following intranasal delivery using a novel bi-directional device

Autor: Agnès Demazières, Anthony Flint, Graeme Hewson, Colin David Sheldrake, Remy Luthringer, Per Gisle Djupesland, Peter Boeijinga, Philippe Danjou

Publikováno v: Journal of Pharmacy and Pharmacology. 61:1219-1228

Objectives The aim was to investigate the pharmacokinetics of intranasal sumatriptan (administered using a novel bi-directional powder delivery device) and study its effects on quantitative electroencephalography in patients with migraine. The safety

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d5a7768b6f9fcd33072094b7e6e733b
https://doi.org/10.1211/jpp.61.09.0012

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Transdermal and Transmucosal Powdered Drug Delivery

Autor: Brian John Bellhouse, Andrew Gordon Muddle, Graeme Hewson, David J. Longridge, David Francis Sarphie, Terry Lee Burkoth

Publikováno v: Critical Reviews in Therapeutic Drug Carrier Systems. 16:331-384

High-velocity powder injection is a promising new drug-delivery technique that provides needle- and pain-free delivery of traditional drugs, drugs from biotechnology such as proteins, peptides, and oligonucleotides as well as traditional and genetic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28d814da266cd652901d8856aad8bae6
https://doi.org/10.1615/critrevtherdrugcarriersyst.v16.i4.10

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Impact of baseline nasal polyp size and previous surgery on efficacy of fluticasone delivered with a novel device: a subgroup analysis

Autor: Per Gisle Djupesland, Graeme Hewson, Ingrid Vlckova

Publikováno v: American journal of rhinologyallergy. 24(4)

Background Little information exists on the impact of baseline polyp size and previous nasal surgery on the efficacy of intranasal steroids. This study was designed to investigate whether baseline polyp size and previous nasal surgery influence the e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6edbd0b3d610865ab4f0809468f8148d
https://pubmed.ncbi.nlm.nih.gov/20615359

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Ketanserin antagonises the anorectic effect of DL-fenfluramine in the rat

Autor: G.E. Leighton, Graeme Hewson, John Hughes, R.G. Hill

Publikováno v: European journal of pharmacology. 145(2)

To determine the role played by 5-HT2 receptors in the anorectic action of DL-fenfluramine, the ability of the selective 5-HT2 receptor antagonist ketanserin to block the reduction in food intake produced by this drug was investigated in non-deprived

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6ab88d955ce39e425b29d85406cb2d2
https://pubmed.ncbi.nlm.nih.gov/3350043

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