Zobrazeno 1 - 10
of 2 269
pro vyhledávání: '"Grady C"'
Autor:
Joanna Achinger-Kawecka, Fatima Valdes-Mora, Phuc-Loi Luu, Katherine A. Giles, C. Elizabeth Caldon, Wenjia Qu, Shalima Nair, Sebastian Soto, Warwick J. Locke, Nicole S. Yeo-Teh, Cathryn M. Gould, Qian Du, Grady C. Smith, Irene R. Ramos, Kristine F. Fernandez, Dave S. Hoon, Julia M. W. Gee, Clare Stirzaker, Susan J. Clark
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Endocrine therapy resistance occurs often in estrogen receptor positive (ER+) breast cancer. Here, the authors find that 3D epigenome remodelling at ER-bound enhancer-promoter interactions is a key mechanism underlying endocrine resistance.
Externí odkaz:
https://doaj.org/article/fa0958eacf7f42d19237b40a66d1a2d1
Autor:
Amanda Khoury, Joanna Achinger-Kawecka, Saul A. Bert, Grady C. Smith, Hugh J. French, Phuc-Loi Luu, Timothy J. Peters, Qian Du, Aled J. Parry, Fatima Valdes-Mora, Phillippa C. Taberlay, Clare Stirzaker, Aaron L. Statham, Susan J. Clark
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
The architectural protein CTCF is a mediator of chromatin conformation, but how CTCF binding to DNA is regulated remains poorly understood. Here the authors find that there is a shared subset of CTCF-bound sites resistant to protein depletion in diff
Externí odkaz:
https://doaj.org/article/8b6198ec146c403090e434c6de6028fa
Autor:
Qian Du, Grady C. Smith, Phuc Loi Luu, James M. Ferguson, Nicola J. Armstrong, C. Elizabeth Caldon, Elyssa M. Campbell, Shalima S. Nair, Elena Zotenko, Cathryn M. Gould, Michael Buckley, Kee-Ming Chia, Neil Portman, Elgene Lim, Dominik Kaczorowski, Chia-Ling Chan, Kirston Barton, Ira W. Deveson, Martin A. Smith, Joseph E. Powell, Ksenia Skvortsova, Clare Stirzaker, Joanna Achinger-Kawecka, Susan J. Clark
Publikováno v:
Cell Reports, Vol 36, Iss 12, Pp 109722- (2021)
Summary: DNA replication timing and three-dimensional (3D) genome organization are associated with distinct epigenome patterns across large domains. However, whether alterations in the epigenome, in particular cancer-related DNA hypomethylation, affe
Externí odkaz:
https://doaj.org/article/a960e9f898d54e74a0e23ec3aac378c2
Autor:
Yolanda Colino-Sanguino, Evan M. Cornett, David Moulder, Grady C. Smith, Joel Hrit, Eric Cordeiro-Spinetti, Robert M. Vaughan, Krzysztof Krajewski, Scott B. Rothbart, Susan J. Clark, Fátima Valdés-Mora
Publikováno v:
iScience, Vol 21, Iss , Pp 773-788 (2019)
Summary: Acetylation of the histone variant H2A.Z (H2A.Zac) occurs at active regulatory regions associated with gene expression. Although the Tip60 complex is proposed to acetylate H2A.Z, functional studies suggest additional enzymes are involved. He
Externí odkaz:
https://doaj.org/article/f6cdb89156f743b9b9d7ef0eed864668
Publikováno v:
International Journal of Women's Health, Vol 2016, Iss Issue 1, Pp 191-202 (2016)
Pauline E Osamor, Christine Grady Department of Bioethics, Clinical Center, National Institutes of Health, Bethesda, MD, USA Abstract: Autonomy is considered essential for decision-making in a range of health care situations, from health care seeking
Externí odkaz:
https://doaj.org/article/6b5e2cea5dcd413cbfa619f3d0d46941
Autor:
Betti, S. K., Follette, K., Jorquera, S., Duchêne, G., Mazoyer, J., Bonnefoy, M., Chauvin, G., Pérez, L. M., Boccaletti, A., Pinte, C., Weinberger, A. J., Grady, C., Close, L. M., Defrère, D., Downey, E. C., Hinz, P. M., Ménard, F., Schneider, G., Skemer, A. J., Vaz, A.
We present near-infrared Large Binocular Telescope Interferometer LMIRCam imagery of the disk around the Herbig Ae/Be star AB Aurigae. A comparison of surface brightness at Ks (2.16 ${\mu}$m), H2O narrowband (3.08 ${\mu}$m), and L' (3.7 ${\mu}$m) all
Externí odkaz:
http://arxiv.org/abs/2201.08868
Autor:
García Bengoechea, E., Woods, C. B., Murtagh, E., Grady, C., Fabre, N., Lhuisset, L., Zunquin, G., Aibar, A., Zaragoza Casterad, J., Haerens, L., Verloigne, M., De Cocker, K., Hellebaut, S., Ribeiro, J., Bohn, L., Mota, J., Bois, J. E.
Publikováno v:
Quest (00336297); Jul-Sep2024, Vol. 76 Issue 3, p269-288, 20p
Publikováno v:
In Agricultural Systems August 2024 219
Autor:
Mizuki, T., Kuzuhara, M., Mede, K., Schlieder, J. E., Janson, M., Brandt, T. D., Hirano, T., Narita, N., Wisniewski, J., Yamada, T., Biller, B., Bonnefoy, M., Carson, J. C., McElwain, M. W., Matsuo, T., Turner, E. L., Mayama, S., Akiyama, E., Uyama, T., Nakagawa, T., Kudo, T., Kusakabe, N., Hashimoto, J., Abe, L., Brander, W., Egner, S., Feldt, M., Goto, M., Grady, C. A., Guyon, O., Hayano, Y., Hayashi, M., Hayashi, S. S., Henning, T., Hodapp, K. W., Ishii, M., Iye, M., Kandori, R., Knapp, G. R., Kwon, J., Miyama, S., Morino, J., Moro-Martin, A., Nishimura, T., Pyo, T., Serabyn, E., Suenaga, T., Suto, H., Suzuki, R., Takahashi, Y. H., Takami, M., Takato, N., Terada, H., Thalmann, C., Watanabe, M., Takami, H., Usuda, T., Tamura, M.
We report an orbital characterization of GJ1108Aab that is a low-mass binary system in pre-main-sequence phase. Via the combination of astrometry using adaptive optics and radial velocity measurements, an eccentric orbital solution of $e$=0.63 is obt
Externí odkaz:
http://arxiv.org/abs/1808.04996
Autor:
Olofsson, J., van Holstein, R. G., Boccaletti, A., Janson, M., Thébault, P., Gratton, R., Lazzoni, C., Kral, Q., Bayo, A., Canovas, H., Caceres, C., Ginski, C., Pinte, C., Asensio-Torres, R., Chauvin, G., Desidera, S., Henning, Th., Langlois, M., Milli, J., Schlieder, J. E., Schreiber, M. R., Augereau, J. -C., Bonnefoy, M., Buenzli, E., Brandner, W., Durkan, S., Engler, N., Feldt, M., Godoy, N., Grady, C., Hagelberg, J., Lagrange, A. -M., Lannier, J., Ligi, R., Maire, A. -L., Mawet, D., Ménard, F., Mesa, D., Mouillet, D., Peretti, S., Perrot, C., Salter, G., Schmidt, T., Sissa, E., Thalmann, C., Vigan, A., Abe, L., Feautrier, P., Mignant, D. Le, Moulin, T., Pavlov, A., Rabou, P., Rousset, G., Roux, A.
Debris disks are the intrinsic by-products of the star and planet formation processes. Most likely due to instrumental limitations and their natural faintness, little is known about debris disks around low-mass stars, especially when it comes to spat
Externí odkaz:
http://arxiv.org/abs/1804.01929