Výsledky vyhledávání - "Graciele C M Manica"

Akademický článek

Fibronectin affects transient MMP2 gene expression through DNA demethylation changes in non-invasive breast cancer cell lines.

Autor: Isabela T Pereira, Edneia A S Ramos, Erico T Costa, Anamaria A Camargo, Graciele C M Manica, Liliane M B Klassen, Andressa Chequin, Karin Braun-Prado, Fábio de O Pedrosa, Emanuel M Souza, Fabricio F Costa, Giseli Klassen

Publikováno v: PLoS ONE, Vol 9, Iss 9, p e105806 (2014)

Metastasis accounts for more than 90% of cancer deaths. Cells from primary solid tumors may invade adjacent tissues and migrate to distant sites where they establish new colonies. The tumor microenvironment is now recognized as an important participa

Externí odkaz: https://doaj.org/article/f568db84bdd74ed9a5a6f87942673a62

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Akademický článek

A Non-Toxic Binuclear Vanadium(IV) Complex as Insulin Adjuvant Improves the Glycemic Control in Streptozotocin-Induced Diabetic Rats

Autor: Mateus S. Lopes, Gabriel B. Baptistella, Giovana G. Nunes, Matheus V. Ferreira, Joice Maria Cunha, Kauê Marcel de Oliveira, Alexandra Acco, Maria Luiza C. Lopes, Alexessander Couto Alves, Glaucio Valdameri, Vivian R. Moure, Geraldo Picheth, Graciele C. M. Manica, Fabiane G. M. Rego

Publikováno v: Pharmaceuticals, Vol 17, Iss 4, p 486 (2024)

Diabetes mellitus (DM) complications are a burden to health care systems due to the associated consequences of poor glycemic control and the side effects of insulin therapy. Recently. adjuvant therapies, such as vanadium compounds, have gained attent

Externí odkaz: https://doaj.org/article/e83ef2c85677421784bbdc5685a2402e

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An oxalate-bridged oxidovanadium(iv) binuclear complex that improves the in vitro cell uptake of a fluorescent glucose analog

Autor: Eduardo L. de Sá, Jaísa F. Soares, Graciele C. M. Manica, David L. Hughes, Geraldo Picheth, Lucas Gian Fachini, Francielli S. Santana, Gabriel Barros Baptistella, Fabiane Gomes de Moraes Rego, Susan Webber de Souza, Giovana G. Nunes

The centrosymmetric oxidovanadium(IV) complex (Et3NH)2[{VO(OH2)(ox)}2(μ–ox)] (I), where ox2− = oxalate, was synthesized and characterized by X-ray diffraction (single-crystal and powder, PXRD), thermogravimetric (TGA), magnetic susceptibility (a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c924b193351cee3e94ffe03ba6af837
https://ueaeprints.uea.ac.uk/id/eprint/79146/

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Antitumoral activity of liraglutide, a new DNMT inhibitor in breast cancer cells in vitro and in vivo

Publikováno v: Chemico-Biological Interactions. 349:109641

Breast cancer (BC) is the most frequently diagnosed female cancer and second leading cause of death. Despite the discovery of many antineoplastic drugs for BC, the current therapy is not totally efficient. In this study, we investigated the potential

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc2ab3891b99b13aed787efae06fdf1b
https://doi.org/10.1016/j.cbi.2021.109641

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Comparative analysis of the histopathological and epidemiological profile of ductal and lobular breast carcinomas diagnosed at the Hospital de Clínicas da Universidade Federal do Paraná during the period 2008-2013

Autor: Heloisa Z. Rocha, Edneia A.S. Ramos, Graciele C. M. Manica, Giseli Klassen, Lucia de Noronha

Publikováno v: Jornal Brasileiro de Patologia e Medicina Laboratorial v.55 n.1 2019
Jornal Brasileiro de Patologia e Medicina Laboratorial
Sociedade Brasileira de Patologia (SBP)
instacron:SBP
Jornal Brasileiro de Patologia e Medicina Laboratorial, Volume: 55, Issue: 1, Pages: 69-86, Published: 09 MAY 2019

Introduction: Breast cancer is the second leading cause of cancer death among women worldwide, and epidemiological studies may help understanding its mechanisms. Objective: To carry out a survey of the number of breast cancer cases diagnosed in a per

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74c9f03e13e1c731966abf9650337d6d
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442019000100069

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MMP9 gene expression regulation by intragenic epigenetic modifications in breast cancer

Autor: Graciele C. M. Manica, Mariana Busato Toledo, Giseli Klassen, Emanuel Maltempi de Souza, Valter Antonio de Baura, Andressa Chequin, Fábio O. Pedrosa, Liliane M. B. Klassen, Isis V. Biembengut, Edneia A.S. Ramos, Fabricio F. Costa

Publikováno v: Gene. 642

Breast cancer is the most frequently diagnosed cancer and the leading cause of cancer death among women worldwide. Metastasis remains a major challenge for the clinical management and prognosis of patients with cancer. The metalloprotease MMP-9 plays

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c25176d5a8bf12232e4bcf77172911f
https://pubmed.ncbi.nlm.nih.gov/29162512

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Down regulation of ADAM33 as a Predictive Biomarker of Aggressive Breast Cancer

Autor: Silvio M. Zanata, Iris Rabinovich, Larissa Magalhães Alvarenga, Liliane M. B. Klassen, Fabricio F. Costa, Caroline Ribeiro, Edneia A.S. Ramos, Lucia de Noronha, Marco A. S. Oliveira, Andressa Chequin, Isabela Tiemy Pereira, Ana Paula Martins Sebastião, Emanuel Maltempi de Souza, Giseli Klassen, Graciele C. M. Manica

Publikováno v: Scientific Reports

Breast cancer is a heterogeneous disease with differences in its clinical, molecular and biological features. Traditionally, immunohistochemical markers together with clinicopathologic parameters are used to classify breast cancer and to predict dise

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d6322fea7709e4e0ff082786fd1cf71
http://europepmc.org/articles/PMC5353751

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The roles of ADAM33, ADAM28, IL-13 and IL-4 in the development of lung injuries in children with lethal non-pandemic acute infectious pneumonia

Autor: Juliana Nemetz Kohler, Priscilla do Carmo Gozzo, Giseli Klassen, Graciele C. M. Manica, Sonia Mara Raboni, Vivian Rafaela Telli de Almeida, Emanuele Baurakiades, Lucia de Noronha, Kelly Susana Kunze Larsen, Victor Horácio de Souza Costa

Publikováno v: Journal of Clinical Virology. 61:585-589

ADAM28, ADAM33, IL-13, IL-4 and other cytokines (IL-6 and IL-10) seem to play important roles in the persistence and maintenance of acute inflammatory processes that ultimately lead to lung remodeling and pulmonary fibrosis, which may be responsible

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34720713bef425a57fadfdadbaf3555d
https://doi.org/10.1016/j.jcv.2014.10.004

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ADAM33 as a New Biomarker for Invasive Lobular Breast Carcinoma

Autor: Marco Aurelio, Lucia de Noronha, Fabricio F. Costa, Giseli Klassen, A S Ramos, Graciele C. M. Manica

Publikováno v: Journal of Cancer Science & Therapy.

Invasive ductal carcinoma (IDC) and invasive lobular breast carcinoma (ILC) are the most common malignancies compromising the breast tissue in women worldwide. ILCs tend to form metastasisin remote locations, such as the gastrointestinal tract, perit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::725a18d83a4a847e56985f57b802d646
https://doi.org/10.4172/1948-5956.1000178

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