Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Graciela N. Balerio"'
Publikováno v:
Pharmacology Biochemistry and Behavior. 180:11-21
Previous studies in our laboratory showed an interaction between the GABAergic and opioid systems involved in the analgesic effect of baclofen (BAC). Furthermore, it is known that sex differences exist regarding various pharmacological responses of m
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 140, Iss, Pp 111786-(2021)
There is substantial evidence that GABAB agonist, baclofen, prevents somatic and motivational responses induced by nicotine withdrawal and may target drug cue vulnerabilities in humans. In this context, we explored different aspects associated with t
Publikováno v:
Synapse. 70:187-197
In previous studies we have shown that baclofen, a selective GABAB receptor agonist, prevents the somatic expression and reestablishes the dopamine and μ-opioid receptors levels, modified during naloxone-precipitated morphine withdrawal syndrome in
Publikováno v:
Pharmacology, biochemistry, and behavior. 180
Previous studies in our laboratory showed an interaction between the GABAergic and opioid systems involved in the analgesic effect of baclofen (BAC). Furthermore, it is known that sex differences exist regarding various pharmacological responses of m
Publikováno v:
Synapse. 68:508-517
Previous studies from our laboratory showed that baclofen (BAC, GABAB receptor agonist) prevented the behavioral and neurochemical alterations of nicotine (NIC) withdrawal syndrome. To further investigate the mechanisms underlying these effects, we a
Publikováno v:
Neuropharmacology
Previous studies from our laboratory showed that anxiety-related responses induced by nicotine (NIC), measured by the elevated plus maze, were abolished by 2-OH-saclofen (GABAB receptor antagonist) (1 mg/kg; ip) or the lack of GABAB receptors (GABAB1
Publikováno v:
Neuropharmacology
Nicotine is the main active component of tobacco, and has both acute and chronic pharmacological effects that can contribute to its abuse potential in humans. The aim of the present study was to evaluate a possible role of GABAB receptors in acute an
Publikováno v:
Pharmacological Research. 65:507-513
The aim of the present study was to evaluate the possible involvement of GABA(B) receptors in the anxiolytic- and anxiogenic-like responses induced by nicotine in mice. Animals were exposed to nicotine only once. The acute administration of low (0.05
Publikováno v:
Drug and Alcohol Dependence. 119:e5-e12
Background Nicotine (NIC), the major active component of tobacco, is critical in the maintenance of the smoking habit. The aims of the present study were to analyze the behavioural and neurochemical variations during NIC withdrawal syndrome in mice,
Autor:
Adriana S. Ridolfi, Leonel Joannas, Graciela N. Balerio, María P. Hermida, Edda C. Villaamil, Mónica Olivera, Silvina L. Diaz
Publikováno v:
Biopharmaceutics & Drug Disposition. 28:283-289
It has been shown that the expression of the morphine (MOR) withdrawal syndrome precipitated by naloxone (NAL) is more intense in male mice than in females, but the reasons for this phenomenon remain uncertain. The purpose of the present study was to