Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Graciela L. Mazzone"'
Publikováno v:
Frontiers in Integrative Neuroscience, Vol 15 (2021)
Spinal Cord Injury (SCI) can elicit a progressive loss of nerve cells promoting disability, morbidity, and even mortality. Despite different triggering mechanisms, a cascade of molecular events involving complex gene alterations and activation of the
Externí odkaz:
https://doaj.org/article/96093634855f43dca0892331efd4ca77
Autor:
Damjan Glavač, Miranda Mladinić, Jelena Ban, Graciela L. Mazzone, Cynthia Sámano, Ivana Tomljanović, Gregor Jezernik, Metka Ravnik-Glavač
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 11360 (2022)
Neurodegenerative diseases are one of the greatest medical burdens of the modern age, being mostly incurable and with limited prognostic and diagnostic tools. Amyotrophic lateral sclerosis (ALS) is a fatal, progressive neurodegenerative disease chara
Externí odkaz:
https://doaj.org/article/f27021b138d944b3af8ed8454d26b424
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 17, p 9572 (2021)
The postnatal rodent spinal cord in-vitro is a useful model to investigate early pathophysiological changes after injury. While low dose nicotine (1 µM) induces neuroprotection, how higher doses affect spinal networks is unknown. Using spinal prepar
Externí odkaz:
https://doaj.org/article/54f564dc902f40a6bcfccb2c120dd14a
Publikováno v:
Journal of Neuroscience Research. 101:86-111
Multiple sclerosis (MS) is an autoimmune demyelinating disorder of the central nervous system (CNS), diagnosed at a mean age of 32 years. CNS glia are crucial players in the onset of MS, primarily involving astrocytes and microglia that can cause/all
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 9572, p 9572 (2021)
Kaur, J, Mazzone, G L, Aquino, J B & Nistri, A 2021, ' Nicotine Neurotoxicity Involves Low Wnt1 Signaling in Spinal Locomotor Networks of the Postnatal Rodent Spinal Cord ', International Journal of Molecular Sciences (CD-ROM), vol. 22, no. 17, pp. 1-21 . https://doi.org/10.3390/ijms22179572
International Journal of Molecular Sciences
Volume 22
Issue 17
Kaur, J, Mazzone, G L, Aquino, J B & Nistri, A 2021, ' Nicotine Neurotoxicity Involves Low Wnt1 Signaling in Spinal Locomotor Networks of the Postnatal Rodent Spinal Cord ', International Journal of Molecular Sciences (CD-ROM), vol. 22, no. 17, pp. 1-21 . https://doi.org/10.3390/ijms22179572
International Journal of Molecular Sciences
Volume 22
Issue 17
The postnatal rodent spinal cord in-vitro is a useful model to investigate early pathophysiological changes after injury. While low dose nicotine (1µM) induces neuroprotection, how higher doses affect spinal networks is unknown. Using spinal prepara
Autor:
Romina, Sierra, Sofía, Gómez Bustillo, Polina, Kameneva, Esteban J, Fiore, Graciela L, Mazzone, Maximiliano, Borda, María V, Blanco, Chiara, Usuardi, Alessandro, Furlan, Patrik, Ernfors, Laura, Alaniz, Alejandro D, Montaner, Igor, Adameyko, Jorge B, Aquino
Publikováno v:
Liver international : official journal of the International Association for the Study of the LiverREFERENCES. 40(4)
Liver fibrosis results from cycles of liver damage and scar formation. We herein aimed at analysing neural crest cells and/or bone marrow stromal cells contribution to the liver.Two liver fibrosis and one hepatectomy model were applied on double-tran
Autor:
Andrea Nistri, Priyadharishini Veeraraghavan, Carlota González-Inchauspe, Osvaldo D. Uchitel, Graciela L. Mazzone
Publikováno v:
Neuroscience. 343:398-410
In the spinal cord high extracellular glutamate evokes excitotoxic damage with neuronal loss and severe locomotor impairment. During the cell dysfunction process, extracellular pH becomes acid and may activate acid-sensing ion channels (ASICs) which
Autor:
Raquel Cano, Graciela L. Mazzone, Osvaldo D. Uchitel, Ayelén Ivana Groisman, Nicolas Ivan Bertone, Lucia Tabares
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Acetazolamide (AZ), a molecule frequently used to treat different neurological syndromes, is an inhibitor of the carbonic anhydrase (CA), an enzyme that regulates pH inside and outside cells. We combined fluorescent FM styryl dyes and electrophysiolo
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
The present study identified ATF3 as a novel dynamic marker for ependymal stem/progenitor cells (nestin, vimentin and SOX2 positive) around the central canal of the neonatal or adult rat spinal cord. While quiescent ependymal cells showed cytoplasmic
Publikováno v:
The Neuroscientist. 19:137-144
Amyotrophic lateral sclerosis (Lou Gehrig’s disease) is a devastating neurodegenerative disorder for which the only licensed treatment is riluzole. Although riluzole clinical efficacy is rather limited, its use has important implications for identi