Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Graciani, Nilsa R"'
Autor:
Kopcho, Lisa M a, Ma, Jianhong a, Marcinkeviciene, Jovita a, Lai, Zhihong a, Witmer, Mark R b, Cheng, Janet b, Yanchunas, Joseph b, Tredup, Jeffrey b, Corbett, Martin b, Calambur, Deepa b, Wittekind, Michael b, Paruchuri, Manjula c, Kothari, Dharti c, Lee, Grace c, Ganguly, Subinay c, Ramamurthy, Vidhyashankar d, Morin, Paul E d, Camac, Daniel M d, King, Robert W e, Lasut, Amy L e, Harold Ross, O e, Hillman, Milton C e, Fish, Barbara e, Shen, Keqiang e, Dowling, Randine L a, Kim, Young B a, Graciani, Nilsa R f, Collins, Dale f, Combs, Andrew P f, George, Henry e, Thompson, Lorin A f, Copeland, Robert A a, ∗
Publikováno v:
In Archives of Biochemistry and Biophysics 2003 410(2):307-316
Autor:
Marcinkeviciene, Jovita ‡, §, Luo, Ying ‡, Graciani, Nilsa R. ¶, Combs, Andrew P. ¶, Copeland, Robert A. ‡
Publikováno v:
In Journal of Biological Chemistry 29 June 2001 276(26):23790-23794
Publikováno v:
In Analytical Biochemistry 15 November 1999 275(2):156-161
Autor:
Robert C. Bruckner, Andrew M. Stern, Anne Higley, Graciani Nilsa R, Sandya Mandlekar, Maria Rafalski, Melody Diamond, Ross L. Stein, Eddy W. Yue, Xiang Jiang, Pearl S. Huang, Randine Dowling, Dimeo Susan, Lisa C. Grimminger, Mingzhu Zhang, Zhihong Lai, Amy L. Musselman, Swamy Yeleswaram, Davette L. Behrens, Robert A. Copeland, Andrew P. Combs, Oliff Allen I, Wei Han, Shu-Yun Zhang, Rebecca Taub, Bruce Car, George L. Trainor, Charles F. Albright, Steve P. Seitz, Daniel Hu
Publikováno v:
Molecular Cancer Therapeutics. 4:751-760
Matrix metalloproteinase (MMP)–activated prodrugs were formed by coupling MMP-cleavable peptides to doxorubicin. The resulting conjugates were excellent in vitro substrates for MMP-2, -9, and -14. HT1080, a fibrosarcoma cell line, was used as a mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45501a8fa2fc432573f20a1fa75bdc1c
https://doi.org/10.1158/1535-7163.mct-05-0006
https://doi.org/10.1158/1535-7163.mct-05-0006
Publikováno v:
Journal of Biological Chemistry. 276:23790-23794
Inhibition of beta-site amyloid precursor protein-cleaving enzyme by a statine-based inhibitor has been studied using steady state and stopped-flow methods. A slow onset rate of inhibition has been observed under steady state conditions, and a K(i) o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::264224db858d859ce16909142f8f0c5e
https://doi.org/10.1074/jbc.m101896200
https://doi.org/10.1074/jbc.m101896200
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 7:1371-1376
Solid-phase synthesis was used to generate a focused RGD peptide mimetic library in an effort to identify potent and selective αvβ3 integrin antagonists. Increased activity was observed for compounds possessing a urea linkage to piperazine, with th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d24df17715e6c6f98360935f1f5e8ec
https://doi.org/10.1016/s0960-894x(97)00200-x
https://doi.org/10.1016/s0960-894x(97)00200-x
Publikováno v:
Brain research. 902(2)
Two pharmacologically distinct CRF receptors are distributed in different brain regions and peripheral tissues. Studies suggest that CRF(1) receptors play an important role in mediating the anxiety provoking effects of CRF. In contrast, far less func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b8fef1d5e3fb2c955095a66474d6329
https://pubmed.ncbi.nlm.nih.gov/11384606
https://pubmed.ncbi.nlm.nih.gov/11384606
Publikováno v:
Analytical biochemistry. 275(2)
As a result of the increasing size of chemical libraries, more rapid and highly sensitive strategies are needed to accelerate the process of drug discovery without increasing the cost. One means of accomplishing this is to miniaturize the assays that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1523358e28a5a3d805a3f74bc94cfbf
https://pubmed.ncbi.nlm.nih.gov/10552899
https://pubmed.ncbi.nlm.nih.gov/10552899
Autor:
Pennise, Cynthia R. a, Georgopapadakou, Nafsika H. a, Collins, R.Dale b, Graciani, Nilsa R. b, Pompliano, David L. a, 11To whom correspondence and reprint requests should be addressed. E-mail: david.l.pompliano@dupontpharma.com.
Publikováno v:
In Analytical Biochemistry 15 January 2002 300(2):275-277
Publikováno v:
Analytical Biochemistry; November 15, 1999, Vol. 275 Issue: 2 p156-161, 6p