Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Gracia Porras"'
Autor:
Carlota Tosat-Bitrián, Alicia Avis-Bodas, Gracia Porras, Daniel Borrego-Hernández, Alberto García-Redondo, Angeles Martín-Requero, Valle Palomo
Publikováno v:
Nanomaterials, Vol 11, Iss 3, p 671 (2021)
CdSe quantum dots (QDs) are valuable tools for deciphering molecular mechanisms in cells. Their conjugation with antibodies offers a unique staining source with optimal characteristics, including increased photostability and narrow emission spectra,
Externí odkaz:
https://doaj.org/article/74ad87e9834440e5a0cba2c894ae818d
Autor:
Olmo Martín-Cámara, Marina Arribas, Geoffrey Wells, Marcos Morales-Tenorio, Ángeles Martín-Requero, Gracia Porras, Ana Martínez, Giorgio Giorgi, Pilar López-Alvarado, Isabel Lastres-Becker, J. Carlos Menéndez
Publikováno v:
Journal of medicinal chemistry. 65(3)
16 p.-9 fig.-9 tab.-1 graph. abst.
Hybrid compounds containing structural fragments of the Rho kinase inhibitor fasudil and the NRF2 inducers caffeic and ferulic acids were designed with the aid of docking and molecular mechanics studies. Follow
Hybrid compounds containing structural fragments of the Rho kinase inhibitor fasudil and the NRF2 inducers caffeic and ferulic acids were designed with the aid of docking and molecular mechanics studies. Follow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64f211f0993d73ad164102585af31f71
https://pubmed.ncbi.nlm.nih.gov/34985276
https://pubmed.ncbi.nlm.nih.gov/34985276
Autor:
Gracia Porras, Silvana Ruiz, Inés Maestro, Daniel Borrego-Hernández, Alberto G. Redondo, Ana Martínez, Ángeles Martín-Requero
Publikováno v:
International Journal of Molecular Sciences
Volume 24
Issue 3
Pages: 2847
Volume 24
Issue 3
Pages: 2847
The goal of this work was to elucidate the pathogenic mechanism of an ALS-associated missense mutation, p.Arg573Gly (R573G), in the TBK1 gene. In particular, we seek to analyze the influence of this variant on the cellular levels and the function of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75d431f57c9424c28c1f5ba4953a7762
https://doi.org/10.3390/ijms24032847
https://doi.org/10.3390/ijms24032847
Autor:
Ines Maestro, Laura R. de la Ballina, Gracia Porras, Silvia Corrochano, Eva De Lago, Anne Simonsen, Patricia Boya, Ana Martinez
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 20; Pages: 12676
19 p.-7 fig.
Mitophagy is the selective degradation of mitochondria by autophagy. It promotes the turnover of mitochondria and prevents the accumulation of dysfunctional mitochondria, which can lead to cellular degeneration. Mitophagy is known t
Mitophagy is the selective degradation of mitochondria by autophagy. It promotes the turnover of mitochondria and prevents the accumulation of dysfunctional mitochondria, which can lead to cellular degeneration. Mitophagy is known t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0075da5a470abf53ad7d34426983c953
https://doi.org/10.3390/ijms232012676
https://doi.org/10.3390/ijms232012676
Autor:
Gracia Porras, Claudia Gonzalo-Consuegra, Ángeles Martín-Requero, Eva de Lago, Loreto Martínez-González, Marta Gómez-Almería, Ana Martínez
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 8975, p 8975 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 16
E-Prints Complutense. Archivo Institucional de la UCM
instname
Digital.CSIC. Repositorio Institucional del CSIC
International Journal of Molecular Sciences
Volume 22
Issue 16
E-Prints Complutense. Archivo Institucional de la UCM
instname
Digital.CSIC. Repositorio Institucional del CSIC
14 p.-6 fig.-2 tab.
Amyotrophic Lateral Sclerosis (ALS) is the most common degenerative motor neuron disease in adults. About 97% of ALS patients present TDP-43 aggregates with post-translational modifications, such as hyperphosphorylation, in t
Amyotrophic Lateral Sclerosis (ALS) is the most common degenerative motor neuron disease in adults. About 97% of ALS patients present TDP-43 aggregates with post-translational modifications, such as hyperphosphorylation, in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::119cf6e8bee24d514c63ee7f7febc373
https://www.mdpi.com/1422-0067/22/16/8975
https://www.mdpi.com/1422-0067/22/16/8975
Autor:
Daniel Borrego-Hernández, Sebastián Cerdán, Isabel Lastres-Becker, Gracia Porras, Inés Maestro, Alberto García-Redondo, Ángeles Martín-Requero, Marina Arribas-Blázquez, Patricia Boya, Ana Martínez
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 3007, p 3007 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 6
Biblos-e Archivo. Repositorio Institucional de la UAM
instname
Digital.CSIC. Repositorio Institucional del CSIC
International Journal of Molecular Sciences
Volume 22
Issue 6
Biblos-e Archivo. Repositorio Institucional de la UAM
instname
Digital.CSIC. Repositorio Institucional del CSIC
17 p.-6 fig.-1 tab.
Amyotrophic lateral sclerosis (ALS) is a fatal neurological condition where motor neurons (MNs) degenerate. Most of the ALS cases are sporadic (sALS), whereas 10% are hereditarily transmitted (fALS), among which mutations are
Amyotrophic lateral sclerosis (ALS) is a fatal neurological condition where motor neurons (MNs) degenerate. Most of the ALS cases are sporadic (sALS), whereas 10% are hereditarily transmitted (fALS), among which mutations are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7254b7362a7d2e7761abafd9e2a62df
https://www.mdpi.com/1422-0067/22/6/3007
https://www.mdpi.com/1422-0067/22/6/3007
Autor:
Valle Palomo, Alberto García-Redondo, Alicia Avis-Bodas, Gracia Porras, Carlota Tosat-Bitrián, Daniel Borrego-Hernández, Ángeles Martín-Requero
Publikováno v:
Nanomaterials
Nanomaterials, Vol 11, Iss 671, p 671 (2021)
Volume 11
Issue 3
Nanomaterials, Vol 11, Iss 671, p 671 (2021)
Volume 11
Issue 3
CdSe quantum dots (QDs) are valuable tools for deciphering molecular mechanisms in cells. Their conjugation with antibodies offers a unique staining source with optimal characteristics, including increased photostability and narrow emission spectra,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a0ac02f6027482d86b0afea7952a9a0
https://pubmed.ncbi.nlm.nih.gov/33803158
https://pubmed.ncbi.nlm.nih.gov/33803158
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
26 p.-6 fig.
Podocalyxin (Podxl) has an essential role in the development and function of the kidney glomerular filtration barrier. It is also expressed by vascular endothelia but perinatal lethality of podxl−/− mice has precluded understand
Podocalyxin (Podxl) has an essential role in the development and function of the kidney glomerular filtration barrier. It is also expressed by vascular endothelia but perinatal lethality of podxl−/− mice has precluded understand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d6934b7c3836ad3316e876f1a3950bd
https://doi.org/10.1016/j.ejcb.2016.04.006
https://doi.org/10.1016/j.ejcb.2016.04.006
Autor:
Loreto Martínez-González, Ana Martínez, Siranjeevi Nagaraj, Gracia Porras, Diana Posa, Fernando Bartolome, Ángeles Martín-Requero
Publikováno v:
Molecular Neurobiology
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC. Repositorio Institucional del CSIC
instname
31 p.-5 fig.-1 tab.
Amyotrophic lateral sclerosis (ALS) is a fatal progressive neurodegenerative disorder of still unknown etiology that results in loss of motoneurons, paralysis, and death, usually between 2 and 4 years from onset. There are no
Amyotrophic lateral sclerosis (ALS) is a fatal progressive neurodegenerative disorder of still unknown etiology that results in loss of motoneurons, paralysis, and death, usually between 2 and 4 years from onset. There are no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3da6e324d067de69d3ebe9f17fd4863f
https://pubmed.ncbi.nlm.nih.gov/30030753
https://pubmed.ncbi.nlm.nih.gov/30030753
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
16 p.-6 fig.
The highly sialoglycosylated extracellular domain of podocalyxin (Podxl) is a constituent of the endothelial glycocalyx of most blood vessels but it is unknown if Podxl plays a prominent role in the function of the glycocalyx as a r
The highly sialoglycosylated extracellular domain of podocalyxin (Podxl) is a constituent of the endothelial glycocalyx of most blood vessels but it is unknown if Podxl plays a prominent role in the function of the glycocalyx as a r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98cd00f12a77c1e293726191a77a199e
https://pubmed.ncbi.nlm.nih.gov/29604348
https://pubmed.ncbi.nlm.nih.gov/29604348