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pro vyhledávání: '"Grace Ziegler"'
Autor:
Clive Dennison, Grace Ziegler, Edith Elliott, Mansoureh Sameni, Philip H. Fortgens, Bonnie F. Sloane
Publikováno v:
Pathology oncology research : POR. 1(1)
Alterations in trafficking of cathepsins B and D have been reported in human and animal tumors. In MCF10 human breast epithelial cells, altered trafficking of cathepsin B occurs during their progression from a preneoplastic to neoplastic state. We no
Autor:
Grace Ziegler, Rajesh Bazaz, Jurij Rozhin, Kenneth V. Honn, Bonnie F. Sloane, Mansoureh Sameni, Jozsef Timar
Publikováno v:
Experimental cell research. 214(1)
The process of tumor cell invasion of the basement membrane is proposed to consist of three steps: attachment, local proteolysis and migration. 12-(S)-HETE, a 12-lipoxygenase metabolite of arachidonic acid, upregulates surface expression of integrin
Publikováno v:
Biological chemistry Hoppe-Seyler. 373(7)
Cathepsins B and L and their endogenous inhibitors were evaluated in rat embryo fibroblast lines which have been developed as a model system for the study of malignant progression and metastatic capability. Three groups of lines were analyzed: 1) imm