Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Grace Y. S. Goh"'
Autor:
Dengke K. Ma, Grace Y. S. Goh, Yoonji Jung, Seung-Jae Lee, Arshia Beigi, Youngsook Lee, Yasuyo Yamaoka, Seon Woo A. An, Youngjae Ryu, Dongyeop Lee, Stefan Taubert, Chang Man Ha
Low temperatures slow aging and extend lifespan in many organisms, including Caenorhabditis elegans. However, the metabolic and homeostatic aspects of low temperature-induced longevity remain poorly understood. Here, we show that changes in lipid com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcd29a2604b532184873d00236fe29f2
https://doi.org/10.1101/366153
https://doi.org/10.1101/366153
Publikováno v:
Nucleic Acids Research
The Mediator multiprotein complex ('Mediator') is an important transcriptional coregulator that is evolutionarily conserved throughout eukaryotes. Although some Mediator subunits are essential for the transcription of all protein-coding genes, others
Autor:
Arshia Beigi, Seung-Jae Lee, Gyoo Yeol Jung, Yasuyo Yamaoka, Dongyeop Lee, Stefan Taubert, Yoonji Jung, Youngjae Ryu, Youngsook Lee, Chang Man Ha, Seon Woo A. An, Dengke K. Ma, Jae-Seong Yang, Grace Y. S. Goh
Publikováno v:
PLoS Biology
PLoS Biology, Vol 17, Iss 8, p e3000415 (2019)
PLoS biology, vol 17, iss 8
PLoS Biology, Vol 17, Iss 8, p e3000415 (2019)
PLoS biology, vol 17, iss 8
Low temperatures delay aging and promote longevity in many organisms. However, the metabolic and homeostatic aspects of low-temperature–induced longevity remain poorly understood. Here, we show that lipid homeostasis regulated by Caenorhabditis ele
Autor:
Stefan Taubert, Allan Mah, Ada W. L. Kwong, Marcus Wong, Katherine L. Martelli, Kulveer S. Parhar, Grace Y. S. Goh, Nicole S. Hou
Publikováno v:
Aging Cell
Reactive oxygen species (ROS) play important signaling roles in metazoans, but also cause significant molecular damage. Animals tightly control ROS levels using sophisticated defense mechanisms, yet the transcriptional pathways that induce ROS defens
Autor:
Forum Bhanshali, Johnathan J. Winter, Regina Lai, Grace Y. S. Goh, Kayoung Lee, Elizabeth A. Veal, Stefan Taubert, Kelsie R. S. Doering
Publikováno v:
Aging Cell
Summary Endogenous and exogenous stresses elicit transcriptional responses that limit damage and promote cell/organismal survival. Like its mammalian counterparts, hepatocyte nuclear factor 4 (HNF4) and peroxisome proliferator‐activated receptor α
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162708 (2016)
PLoS ONE
PLoS ONE
Nuclear hormone receptors (NHRs) are transcription factors that regulate numerous physiological and developmental processes and represent important drug targets. NHR-49, an ortholog of Hepatocyte Nuclear Factor 4 (HNF4), has emerged as a key regulato