Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Grace X Y, Zheng"'
Autor:
Grace X. Y. Zheng, Jessica M. Terry, Phillip Belgrader, Paul Ryvkin, Zachary W. Bent, Ryan Wilson, Solongo B. Ziraldo, Tobias D. Wheeler, Geoff P. McDermott, Junjie Zhu, Mark T. Gregory, Joe Shuga, Luz Montesclaros, Jason G. Underwood, Donald A. Masquelier, Stefanie Y. Nishimura, Michael Schnall-Levin, Paul W. Wyatt, Christopher M. Hindson, Rajiv Bharadwaj, Alexander Wong, Kevin D. Ness, Lan W. Beppu, H. Joachim Deeg, Christopher McFarland, Keith R. Loeb, William J. Valente, Nolan G. Ericson, Emily A. Stevens, Jerald P. Radich, Tarjei S. Mikkelsen, Benjamin J. Hindson, Jason H. Bielas
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Single-cell gene expression analysis is challenging. This work describes a new droplet-based single cell RNA-seq platform capable of processing tens of thousands of cells across 8 independent samples in minutes, and demonstrates cellular subtypes and
Externí odkaz:
https://doaj.org/article/9c33171e807745c7908a1e1e9a3712e3
Autor:
Grace X Y Zheng, Arvind Ravi, J Mauro Calabrese, Lea A Medeiros, Oktay Kirak, Lucas M Dennis, Rudolf Jaenisch, Christopher B Burge, Phillip A Sharp
Publikováno v:
PLoS Genetics, Vol 7, Iss 5, p e1002054 (2011)
MicroRNAs (miRNAs) post-transcriptionally regulate the expression of thousands of distinct mRNAs. While some regulatory interactions help to maintain basal cellular functions, others are likely relevant in more specific settings, such as response to
Externí odkaz:
https://doaj.org/article/28ea26b79fe44691af7a315965fefd32
Autor:
Jeffrey M, Granja, Sandy, Klemm, Lisa M, McGinnis, Arwa S, Kathiria, Anja, Mezger, M Ryan, Corces, Benjamin, Parks, Eric, Gars, Michaela, Liedtke, Grace X Y, Zheng, Howard Y, Chang, Ravindra, Majeti, William J, Greenleaf
Publikováno v:
Nature biotechnology. 37(12)
Identifying the causes of human diseases requires deconvolution of abnormal molecular phenotypes spanning DNA accessibility, gene expression and protein abundance
Autor:
Kelley S, Yan, Claudia Y, Janda, Junlei, Chang, Grace X Y, Zheng, Kathryn A, Larkin, Vincent C, Luca, Luis A, Chia, Amanda T, Mah, Arnold, Han, Jessica M, Terry, Akifumi, Ootani, Kelly, Roelf, Mark, Lee, Jenny, Yuan, Xiao, Li, Christopher R, Bolen, Julie, Wilhelmy, Paige S, Davies, Hiroo, Ueno, Richard J, von Furstenberg, Phillip, Belgrader, Solongo B, Ziraldo, Heather, Ordonez, Susan J, Henning, Melissa H, Wong, Michael P, Snyder, Irving L, Weissman, Aaron J, Hsueh, Tarjei S, Mikkelsen, K Christopher, Garcia, Calvin J, Kuo
Publikováno v:
Nature. 545(7653)
The canonical Wnt/β-catenin signalling pathway governs diverse developmental, homeostatic and pathological processes. Palmitoylated Wnt ligands engage cell-surface frizzled (FZD) receptors and LRP5 and LRP6 co-receptors, enabling β-catenin nuclear