Výsledky vyhledávání - "Grace W. K. Wong"

Identification of a Treponema denticola OppA Homologue That Binds Host Proteins Present in the Subgingival Environment

Autor: Muneaki Tamura, Roger A. Chan, J. Christopher Fenno, Grace W. K. Wong, Barry C. McBride, Pauline M. Hannam

Publikováno v: Infection and Immunity. 68:1884-1892

Proteins secreted or exported by Treponema denticola have been implicated as mediators of specific interactions between the spirochete and subgingival tissues in periodontal diseases. However, limited information is available on the ability of this p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21c60835a600a09b12707949b5e97c70
https://doi.org/10.1128/iai.68.4.1884-1892.2000

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Conservation of msp, the gene encoding the major outer membrane protein of oral Treponema spp

Autor: J C Fenno, K H Müller, Wai K. Leung, Barry C. McBride, Grace W. K. Wong, Pauline M. Hannam

Publikováno v: Journal of Bacteriology. 179:1082-1089

The major surface protein (Msp) of Treponema denticola has been implicated as a mediator of the interaction between the spirochete and the gingival epithelium in periodontal diseases. Previous studies showed that the Msp of T. denticola ATCC 35405 ha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e89646f3103308205c518daeb1ffa69c
https://doi.org/10.1128/jb.179.4.1082-1089.1997

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Cleavage of Treponema denticola PrcA Polypeptide To Yield Protease Complex-Associated Proteins Prca1 and Prca2 Is Dependent on PrtP

Autor: Pauline M. Hannam, Grace W. K. Wong, Barry C. McBride, Si Young Lee, Xue Lin Bian, J. Christopher Fenno

Analysis of potential virulence factors of oral spirochetes focuses on surface and secreted proteins. The Treponema denticola chymotrypsin-like protease (CTLP) is implicated in degradation of host cell molecules and contributes to tissue invasion. Th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e38c76ead75a9b59aeef9d52c4026c4
https://europepmc.org/articles/PMC135188/

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Mutagenesis of outer membrane virulence determinants of the oral spirochete Treponema denticola

Autor: Barry C. McBride, J. Christopher Fenno, Pauline M. Hannam, Grace W. K. Wong

Publikováno v: FEMS microbiology letters. 163(2)

The pore-forming major surface protein (Msp) and the chymotrypsin-like protease (CTLP) of Treponema denticola ATCC 35405 have been implicated in periodontal pathogenicity. Allelic replacement mutations were constructed at two sites in the msp gene an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c963d2426abf9e5876ecdf8fd2dc0830
https://pubmed.ncbi.nlm.nih.gov/9673024

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