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Akademický článek

The relative potential contribution of volume load and vascular mechanisms to hypertension in non-dialysis and dialysis chronic kidney disease patients

Autor: Grace Tade, Hon-Chun Hsu, Chanel Robinson, Noluntu Dlongolo, Gloria Teckie, Ahmed Solomon, Patrick Hector Dessein

Publikováno v: Frontiers in Cardiovascular Medicine, Vol 11 (2024)

BackgroundHypertension is highly prevalent and particularly difficult to treat adequately in patients with chronic kidney disease (CKD). The relative contribution of volume overload and vascular mechanisms to blood pressure measures in CKD and whethe

Externí odkaz: https://doaj.org/article/6a8a4cab6dea4b2d93c02a95a831e685

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Akademický článek

Role of atrial natriuretic peptide in the dissociation between flow relations with ventricular mass and function in a community with volume-dependent hypertension

Autor: Suraj M. Yusuf, Gavin R. Norton, Vernice R. Peterson, Nonhlanhla Mthembu, Carlos D. Libhaber, Grace Tade, Hamza Bello, Adamu J. Bamaiyi, Keneilwe N. Mmopi, Patrick H. Dessein, Ferande Peters, Pinhas Sareli, Angela J. Woodiwiss

Publikováno v: Frontiers in Cardiovascular Medicine, Vol 10 (2023)

BackgroundWhether differential effects of volume load on left ventricular mass (LVM) and function occur in sustained volume-dependent primary hypertension, and the impact of atrial natriuretic peptide (ANP) on these effects, is unknown.MethodsFrom ao

Externí odkaz: https://doaj.org/article/e53a4cf1f1144bc4be90bbefe3b2786d

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Akademický článek

Proximal aortic stiffness modifies the relationship between heart rate and backward wave and hence central arterial pulse pressure

Autor: Nonhlanhla Mthembu, Vernice R. Peterson, Gavin R. Norton, Eitzaz Sadiq, Andrea Kolkenbeck-Ruh, Ravi Naran, Suraj M. Yusuf, Grace Tade, Hamza Bello, Adamu Bamaiyi, Carlos D. Libhaber, Patrick Dessein, Ferande Peters, Taalib Monareng, Talib Abdool-Carrim, Ismail Cassimjee, Pinhas Sareli, Girish Modi, Angela J. Woodiwiss

Publikováno v: Frontiers in Cardiovascular Medicine, Vol 9 (2022)

AimsA lower heart rate (HR) increases central blood pressure through enhanced backward wave pressures (Pb). We aimed to determine whether these relationships are modified by increases in aortic stiffness.MethodsUsing non-invasive central pressure, ao

Externí odkaz: https://doaj.org/article/e3f3aeee31f94464912d9f093f56c3e0

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Associations of Traditionally Determined Left Ventricular Mass Indices and Hemodynamic and Non-Hemodynamic Components of Cardiac Remodeling with Diastolic and Systolic Function in Patients with Chronic Kidney Disease

Autor: Dessein, Hon-Chun Hsu, Grace Tade, Chanel Robinson, Noluntu Dlongolo, Gloria Teckie, Ahmed Solomon, Angela Jill Woodiwiss, Patrick Hector

Publikováno v: Journal of Clinical Medicine; Volume 12; Issue 13; Pages: 4211

We aimed to evaluate the extent to which different left ventricular mass parameters are associated with left ventricular function in chronic kidney disease (CKD) patients. We compared the associations between traditionally determined left ventricular

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=multidiscipl::8b1d7ce21b8d147b4d2ac8dcd3d36372

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Contribution of Increases in Late Systolic Ejection Volume to the Impact of Heart Rate on Central Arterial Pulse Pressure in a Community Sample

Autor: Nonhlanhla Mthembu, Gavin R Norton, Vernice R Peterson, Ravi Naran, Suraj M Yusuf, Grace Tade, Hamza Bello, Adamu Bamaiyi, Carlos D Libhaber, Patrick Dessein, Ferande Peters, Pinhas Sareli, Angela J Woodiwiss

Publikováno v: American Journal of Hypertension. 35:989-997

BACKGROUND A lower heart rate (HR) increases left ventricular (LV) ejection volume. Whether this contributes to the adverse effects of HR on central pulse pressure (PPc) through reservoir volume effects is uncertain. METHODS Using noninvasive central

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::096ae19243e4067d9e07f970a43a625d
https://doi.org/10.1093/ajh/hpac097

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Aortic Stiffness and Pulsatile Pressures as Potential Mediators of Chronic Kidney Disease Induced Impaired Diastolic Function

Autor: Hon-Chun Hsu, Grace Tade, Gavin R Norton, Ferande Peters, Chanel Robinson, Noluntu Dlongolo, Gloria Teckie, Angela J Woodiwiss, Patrick H Dessein

Publikováno v: International Journal of Nephrology and Renovascular Disease. 15:27-40

Hon-Chun Hsu,1,2,* Grace Tade,1,* Gavin R Norton,1 Ferande Peters,1 Chanel Robinson,1 Noluntu Dlongolo,3 Gloria Teckie,4 Angela J Woodiwiss,1 Patrick H Dessein1,5 1Cardiovascular Pathophysiology and Genomics Research Unit, School of Physiolog

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::872db795bc5e43f22cd015af5032c690
https://doi.org/10.2147/ijnrd.s346074

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Attenuated Relationships Between Indexes of Volume Overload and Atrial Natriuretic Peptide in Uncontrolled, Sustained Volume-Dependent Primary Hypertension

Autor: Suraj M. Yusuf, Gavin R. Norton, Vernice R. Peterson, Nico Malan, Monica Gomes, Nonhlanhla Mthembu, Carlos D. Libhaber, Grace Tade, Hamza Bello, Adamu J. Bamaiyi, Keneilwe N. Mmopi, Ferande Peters, Pinhas Sareli, Patrick H. Dessein, Angela J. Woodiwiss

Publikováno v: Hypertension (Dallas, Tex. : 1979). 80(1)

Background: Whether systolic blood pressure (SBP) control in sustained volume-dependent primary hypertension is associated with blunted ANP (atrial natriuretic peptide) relationships with indexes of volume load is unknown. Methods: Systemic hemodynam

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25c7514f5e7762fe6a9494564d97a118
https://pubmed.ncbi.nlm.nih.gov/36330806

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Independent relationships between renal mechanisms and systemic flow, but not resistance to flow in primary hypertension in Africa

Autor: Patrick H Dessein, Gavin R. Norton, Keneilwe N. Mmopi, Vernice R. Peterson, Ferande Peters, Nico Malan, Elena Libhaber, Carlos D. Libhaber, Pinhas Sareli, Angela J. Woodiwiss, Daniel Da Silva Fernandes, Grace Tade, Hamza Bello, Suraj M. Yusuf, Nonhlanhla Mthembu, Mohlabani Masiu

Publikováno v: Journal of Hypertension. 39:2446-2454

AIMS Whether renal mechanisms of hypertension primarily translate into increases in systemic vascular resistance (SVR) in all populations is uncertain. We determined whether renal mechanisms associate with either increases in SVR (and impedance to fl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::355a6dee5de793bd421ef2abfaafd1e9
https://doi.org/10.1097/hjh.0000000000002968

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Distinct Contribution of Systemic Blood Flow to Hypertension in an African Population Across the Adult Lifespan

Autor: Daniel Da Silva Fernandes, Angela J. Woodiwiss, Hamza Bello, Pinhas Sareli, Grace Tade, Nonhlanhla Mthembu, Carlos D. Libhaber, Ferande Peters, Gavin R. Norton, Vernice R. Peterson, Mohlabani Masiu, Keneilwe N. Mmopi

Publikováno v: Hypertension. 76:410-419

Although hypertension in groups of African ancestry is volume-dependent, the relative impact of systemic flow (stroke volume, peak aortic flow [Q]) versus vascular mechanisms (systemic vascular resistance, aortic characteristic impedance [Zc], total

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9922898b3b652dc82f8b356b9a71f212
https://doi.org/10.1161/hypertensionaha.120.14925

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