Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Grace Simoni"'
Publikováno v:
Artificial Organs. 38:684-690
Effective artificial oxygen carriers may offer a solution to tackling current transfusion medicine challenges such as blood shortages, red blood cell storage lesions, and transmission of emerging pathogens. These products, could provide additional th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85f16393b382cc85949ec4b473e40222
https://doi.org/10.1111/aor.12337
https://doi.org/10.1111/aor.12337
Publikováno v:
Artificial Organs. 36:139-150
An effective hemoglobin (Hb)-based blood substitute that acts as a physiological oxygen carrier and volume expander ought to stimulate erythropoiesis. A speedy replacement of blood loss with endogenous red blood cells should be an essential feature o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b22d1eaba5b74040b72e5842ccac1f69
https://doi.org/10.1111/j.1525-1594.2011.01431.x
https://doi.org/10.1111/j.1525-1594.2011.01431.x
Autor:
Kenneth Nugent, Yasir Yaqub, Jose A. Suarez, Grace Simoni, Jan Simoni, Rosalinda Jimenez, Alejandro Perez-Verdia, Warangkana Chokesuwattanaskul
Publikováno v:
Cardiology. 116:253-256
Background: Peroxisome proliferator-activated receptor (PPAR) agonists can favorably influence atheroma proliferation, lipoprotein metabolism and macrovascular complications. Pioglitazone, one of the thiazolidinedione compounds, is a PPAR ligand acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d52934947caf4ac615ddbcb361bfe7a
https://doi.org/10.1159/000318024
https://doi.org/10.1159/000318024
Autor:
Chanwit Roongsritong, Gary Meyerrose, Cihan Cevik, Jan Simoni, Mohammad Otahbachi, Grace Simoni, John F. Moeller
Publikováno v:
Journal of Thrombosis and Thrombolysis. 30:184-191
This study evaluated gender variability in platelet aggregation in response to common agonists. Platelet aggregation was measured in 36 healthy men and women free of any antiplatelet medication, aged 22-36 years, of Caucasian (White not of Hispanic o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::704a09881eb645570a2f63cdb9e5d045
https://doi.org/10.1007/s11239-009-0436-x
https://doi.org/10.1007/s11239-009-0436-x
Publikováno v:
Artificial Organs. 33:115-126
Uncontrolled oxidative reactions of hemoglobin (Hb) are still the main unresolved problem for Hb-based blood substitute developers. Spontaneous oxidation of acellular ferrous Hb into a nonfunctional ferric Hb generates superoxide anion. Hydrogen pero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa414ab6354c73d525bb395b69b802f2
https://doi.org/10.1111/j.1525-1594.2008.00695.x
https://doi.org/10.1111/j.1525-1594.2008.00695.x
Publikováno v:
Artificial Cells, Blood Substitutes, and Biotechnology. 35:191-210
Despite the tremendous progress in research on hemoglobin (Hb) cellular and molecular responses, the current understanding of Hb's overall intrinsic toxicity is still limited. The complete mechanism of Hb-induced vasoconstriction has not yet been est
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abb643b9b7cc0f785e1ef6daa7b283d1
https://doi.org/10.1080/10731190601188273
https://doi.org/10.1080/10731190601188273
Autor:
Chanwit Roongsritong, John F. Moeller, James P. Tsikouris, John A. Griswold, Donald E. Wesson, Apurv Khanna, Grace Simoni, Jan Simoni
Publikováno v:
ASAIO Journal. 52:652-661
Free hemoglobin (Hb) during autoxidation increases 8-iso-prostaglandin-F2-alpha (8-isoprostane) formation in vitro. Because 8-isoprostane and plasma Hb are elevated in chronic renal failure (CRF), we evaluated the role of Hb in this iso-prostane synt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67a7537d429ca05849ec9334f776bb80
https://doi.org/10.1097/01.mat.0000235282.89757.9f
https://doi.org/10.1097/01.mat.0000235282.89757.9f
Publikováno v:
Artificial organs. 38(8)
Effective artificial oxygen carriers may offer a solution to tackling current transfusion medicine challenges such as blood shortages, red blood cell storage lesions, and transmission of emerging pathogens. These products, could provide additional th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b23a3ca9c58e2040b19fc7825437ad8e
https://pubmed.ncbi.nlm.nih.gov/24980041
https://pubmed.ncbi.nlm.nih.gov/24980041
Autor:
Jan Simoni, Ramana Vijay Kumar, Grace Simoni, Raul Martinez-Zaguilan, Charles D. Lox, Donald E. Wesson, Samuel D. Prien
Publikováno v:
ASAIO Journal. 44:M356-M367
The authors have previously documented that appropriate chemical and pharmacologic modification of the hemoglobin molecule are required to attenuate certain pathophysiologic reactions of the reticuloendothelium. The current study further investigates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5735214cfe568b4d77ab5cb0f5caf1a
https://doi.org/10.1097/00002480-199809000-00007
https://doi.org/10.1097/00002480-199809000-00007
Publikováno v:
Emerging Therapeutic Targets. 2:85-91
(1998). An improved blood substitute. Emerging Therapeutic Targets: Vol. 2, No. 1, pp. 85-91.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2068fce0e0ef12529b9a479ff01471ea
https://doi.org/10.1517/14728222.2.1.85
https://doi.org/10.1517/14728222.2.1.85